Salflu 100 Rotacap 10pcs

✔️ Uses of Salflu 100 Rotacap

• Treatment of Chronic obstructive pulmonary disease (COPD)
• Treatment of Asthma

✔️ How does Salflu 100 Rotacap work?

• Salmeterol is a long-acting bronchodilator that works by relaxing the muscles in the airways and widening the airways.
• Fluticasone Propionate is a steroid. It works by stopping the release of certain chemical messengers that cause inflammation (swelling) of the airways. Together, they make breathing easier.

✔️ Side Effects of Salflu 100 Rotacap

• Salmeterol: Tremors, palpitations, headache, arrhythmia, muscle cramps.
• Fluticasone: Hoarseness, oral thrush, hypersensitivity reactions.

✔️ Quick Suggestions:

• This medication is intended for inhalation use only and should not be swallowed. It should be taken at the same time each day for consistency.
• It does not provide immediate relief and should not be used for sudden breathing difficulties.
• In such cases, a rescue inhaler should be used.
• Dry mouth is a potential side effect, which can be alleviated by frequent rinsing, maintaining good oral hygiene, increasing water intake, or using sugarless candy.
• To prevent fungal infections in the mouth and throat, gargle with warm water after each use.
• The first dose should be taken under medical supervision, as it may cause wheezing or airway tightening (bronchospasm) immediately after inhalation.
• Your doctor may periodically check your blood potassium levels, as low oxygen levels (hypoxia) and medications like Salflu 100 Rotacap can lower potassium.
• Only a small amount of the medicine is absorbed into the bloodstream after inhalation, so severe side effects are unlikely.

✔️ Indication of Salflu 100 Rotacap

The Salflu Inhalation Capsule is a combination of Salmeterol (50 mcg) and Fluticasone Propionate (100 mcg or more), used primarily for the regular treatment of asthma in patients who need both a long-acting beta-2 agonist (Salmeterol) and an inhaled corticosteroid (Fluticasone). It is beneficial for patients who either:

1. Are inadequately controlled with inhaled corticosteroids and need a long-acting bronchodilator.
2. Are already controlled on both a long-acting beta-agonist and inhaled corticosteroids.

✔️ Pharmacology

• Salmeterol: A long-acting beta-2 agonist that relaxes airway muscles for up to 12 hours, reducing asthma symptoms.
• Fluticasone Propionate: A corticosteroid that reduces lung inflammation, improving lung function and reducing exacerbations.

✔️ Dosage & Administration of Salflu 100 Rotacap

Adult Dose:

For Asthma (Inhalation):

Inhalation powder (Salmeterol 50 mcg + Fluticasone Propionate 100/250/500 mcg per dose):
1 inhalation twice daily (bid).

Pressurized inhalation (Salmeterol 25 mcg + Fluticasone Propionate 50/125/250 mcg per dose):
2 inhalations twice daily (bid).

For Chronic Obstructive Pulmonary Disease (COPD):

• Inhalation powder (Salmeterol 50 mcg + Fluticasone Propionate 500 mcg per dose):
  1 inhalation twice daily (bid).

Child Dose (Ages 4-12):

For Asthma (Inhalation):

Inhalation powder (Salmeterol 50 mcg + Fluticasone Propionate 100 mcg per dose):
1 inhalation twice daily (bid).

Pressurized inhalation (Salmeterol 25 mcg + Fluticasone Propionate 50 mcg per dose):
2 inhalations twice daily (bid).

Child Dose (Ages 12 and older):

For Asthma (Inhalation):

Inhalation powder (Salmeterol 50 mcg + Fluticasone Propionate 100/250/500 mcg per dose):
1 inhalation twice daily (bid).

Pressurized inhalation (Salmeterol 50 mcg + Fluticasone Propionate 50/125/250 mcg per dose):
2 inhalations twice daily (bid).

✔️ Interaction

• Beta-blockers (non-selective and selective): Should be avoided in patients with asthma, as they may reduce the efficacy of beta-agonists like Salmeterol. Use is only considered if necessary.
• CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): Caution is required as these medications can increase systemic exposure to Fluticasone Propionate, raising the risk of side effects, particularly corticosteroid-related.

✔️ Contraindications

• Hypersensitivity: Contraindicated in patients with a known allergy to Salmeterol, Fluticasone Propionate, or any of the excipients.
• Acute Asthma: Not to be used as primary treatment for status asthmaticus or acute asthma episodes, where immediate intensive measures are necessary.

✔️ Pregnancy & Lactation

Use only if the benefits outweigh the potential risks, as data on human pregnancy and breastfeeding are limited.

✔️ Precautions & Warnings

• Not suitable for treating acute asthma attacks.
• Should be used regularly, even if asymptomatic, to maintain asthma control.
• Caution in patients with severe liver impairment or on strong CYP3A4 inhibitors (e.g., ketoconazole).

✔️ Storage:

Store below 30°C, away from direct sunlight and heat. Avoid puncturing or incinerating the canister.