Seraflo | (Salmeterol Xinafoate + Fluticasone Propionate)
Regular maintenance treatment of asthma in patients:
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Proper Packaging
Salmeterol: Tremor, palpitations, headache, arrhythmias, arthralgia, hypersensitivity reactions.
Fluticasone: Hoarseness, oral thrush, hypersensitivity reactions, rare facial/oropharyngeal edema.
Asthma (≥12 years):
Asthma (4–12 years): 25/50 µg: 2 puffs twice daily
Inhalation Capsule / Maxhaler: 50/100 µg, 50/250 µg, or 50/500 µg twice daily depending on severity.
COPD: 50/250 µg twice daily
Key Administration Advice
Avoid non-selective β-blockers unless essential.
Caution with strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) due to risk of increased Fluticasone exposure.
Hypersensitivity to active ingredients or excipients.
Primary treatment of status asthmaticus or acute asthma episodes.
Use only if benefits outweigh risks; safety data in humans are limited.
Do not start during an asthma exacerbation.
Monitor for pneumonia in COPD patients.
High doses over long periods may cause systemic corticosteroid effects (adrenal suppression, growth retardation in children, decreased bone density, cataract, glaucoma).
Store below 30 °C, away from direct sunlight. Pressurized canister—do not puncture or incinerate. Keep out of reach of children.
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