Unilin: (Theophylline)
Therapeutic Class: Bronchodilator (Methylxanthine derivative)
Formulation: Sustained-release oral preparation
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Unilin is recommended for the treatment and control of various respiratory conditions, including:
Theophylline, a methylxanthine bronchodilator, works by relaxing bronchial smooth muscles and suppressing airway hyperresponsiveness. It also enhances diaphragmatic contractility, improving breathing efficiency.
Half-life: Variable (3–9 hours in non-smoking adults), influenced by age, liver function, concurrent medications, and smoking status.
Dosage must be individualized based on serum theophylline levels to ensure optimal therapeutic effect and minimize toxicity.
Sustained-release formulations are typically given every 12 hours in adults, and every 8 hours in some children with rapid drug metabolism.
Recommended Maintenance Dosage:
Known hypersensitivity to theophylline or any component of the formulation
Use during pregnancy only if necessary, as effects on the fetus are not well-established
Theophylline is excreted in breast milk; monitor infants for signs of irritability or mild toxicity
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