Calcium Carbonate neutralizes gastric acid by reacting with hydrochloric acid in the stomach:
CaCO₃ + 2HCl → CaCl₂ + H₂O + CO₂
This reaction increases gastric pH, reducing the activity of pepsin and alleviating acidity. Up to 30% of the orally administered calcium may be absorbed from the gastrointestinal tract.
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Orthocal Tablet (Calcium Carbonate)
Orthocal 250 mg or 500 mg tablets are indicated for the treatment and prevention of calcium deficiency when dietary intake is inadequate.
Conditions that may require supplementation include:
Orthocal is also used in the management of hyperphosphataemia in patients with chronic renal failure, including those on hemodialysis or continuous ambulatory peritoneal dialysis (CAPD). In such cases, it helps bind excess phosphate and may be used alongside dietary phosphate restriction or aluminum hydroxide if required.
Additionally, Orthocal can provide short-term relief of dyspeptic symptoms, though it is not recommended for long-term use in peptic ulcer disease.
Orthocal 1000 mg tablet is indicated for the symptomatic relief of acidity-related disorders such as:
For 250 mg or 500 mg tablet:
As a calcium supplement: 1250–3750 mg Calcium Carbonate (equivalent to 500–1500 mg elemental calcium) daily.
For 1000 mg tablet:
Children: Safe and effective in pediatric patients with chronic renal failure.
Elderly: May experience constipation; regular monitoring of serum calcium and phosphate is advised.
May enhance cardiac effects of digoxin or other cardiac glycosides if hypercalcemia occurs.
May reduce absorption of tetracycline antibiotics when taken together.
In chronic renal failure, Vitamin D therapy may need adjustment to avoid hypercalcemia when Orthocal is used as a phosphate binder.
Use cautiously in patients with sarcoidosis, renal impairment, or cardiac disease.
Gastrointestinal irritation or constipation may occur.
Hypercalcemia is rare but may develop with excessive doses or in patients with renal failure.
Calcium carbonate has a long history of safe use during pregnancy and lactation as a dietary supplement and antacid.
Store in a cool, dry place at controlled room temperature, protected from light and moisture.
Keep out of reach of children.
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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.