Bicalon 50 | Bicalutamide | Prostate cancer
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Bicalon 50mg Tablet 14pcs

Generic: Bicalutamide

Type: Tablet

Pack Size: 14s pack

  • Bicalon/Bicalutamide is a non-steroidal androgen receptor inhibitor that blocks androgen action by binding to cytosol androgen receptors in target tissues. Prostate carcinoma, being androgen-sensitive, responds to treatments that inhibit androgen effects or remove androgen sources.
  • Used in combination with a luteinizing hormone-releasing hormone (LHRH) analog for the treatment of Stage D2 metastatic carcinoma of the prostate.
  • রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন (Take under the guidance of a registered physician).

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MRP: ৳ 420 5% Off

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✅ Description:

Bicalutamide

  • Treatment of prostate cancer, particularly advanced or metastatic stages (e.g., Stage D2 carcinoma).
  • May also treat other androgen-dependent conditions as determined by a physician.
  • Contraindicated in pregnancy as it can cause fetal harm.
  • Not indicated for use in females.
  • Monitor PT/INR when used with coumarin anticoagulants.
  • Gynecomastia and breast pain: Reported with higher doses (150 mg).
  • Blood glucose monitoring: Consider patients using Bicalon with LHRH agonists due to potential reduction in glucose tolerance.
  • Regular monitoring is recommended; assess clinical progression if PSA levels increase.

Safety Advices


Alcohol
UNSAFE

Avoid alcohol while on Bicalon 50, as it can increase the risk of liver problems and interfere with the medication's effectiveness.


Pregnancy
UNSAFE

Bicalon 50 is contraindicated in pregnant women as it is not approved for use in women. Please consult a doctor if you are pregnant or planning for pregnancy.


UNSAFE

Bicalon 50 is contraindicated in breastfeeding women as it is not approved for use in women. Please consult a doctor if you are breastfeeding.


Breastfeeding
CONSULT YOUR DOCTOR

Bicalon 50 may cause drowsiness in some people. Therefore, avoid driving if you are drowsy after taking Bicalon 50


CONSULT YOUR DOCTOR

Take Bicalon 50 with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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✔️ How does Bicalon 50 work?
  • Bicalutamide is a non-steroidal androgen receptor inhibitor.
  • It blocks the effects of male hormones (androgens), such as testosterone, by binding to androgen receptors, which prevents the growth of prostate cancer cells.
Pack Image of Pack Image: Bicalon 50 mg Tablet (2 x 14)
✔️ Dosage and Administration of Bicalon 50
  • Adult Dose:
    • Recommended Dose: One 50 mg tablet daily (morning or evening), with or without food.
  • Pediatric Use:
    • Safety and effectiveness have not been established in pediatric patients.
  • Hepatic Impairment:
    • Use with caution in patients with moderate-to-severe hepatic impairment as the drug is extensively metabolized by the liver.
✔️ Adverse effects (seen in more than 10% of patients):

Hot flashes, pain (general, back, pelvic, abdominal), asthenia, constipation, infection, nausea, peripheral edema, dyspnea, diarrhea, hematuria, nocturia, anemia.

✔️ Quick Suggestions:
  1. Take at the same time daily for consistency.
  2. Avoid stopping the medication without consulting your doctor.
  3. Watch for signs of liver damage or severe side effects and report them immediately.
  4. Attend all follow-up appointments for blood tests to monitor liver function and PSA levels.
  5. Practice effective contraception during treatment.
✔️ Overdose Effects of Bicalon 50
  • Clinical trials with doses up to 200 mg daily were well-tolerated.
  • No specific antidote; symptomatic treatment is recommended in case of overdose.
✔️ Serious Side Effects Requiring Immediate Attention
  • Liver Damage: Yellowing of skin/eyes, dark urine, stomach pain.
  • Anemia: Symptoms include fatigue and shortness of breath.
  • Skin sensitivity to sunlight: Avoid excessive exposure and use sunscreen.
✔️ Drug Interactions
  • Coumarin Anticoagulants: Bicalutamide enhances the effects of anticoagulants such as warfarin.
    • Monitor Prothrombin Time (PT) and INR regularly.
✔️ Contraindications
  • Hypersensitivity to Bicalutamide or its components.
  • Not indicated for women, children, or during pregnancy and lactation.
✔️ Precautions & Warnings
  • Regular liver function tests are advised during long-term therapy.
  • Monitor Prostate-Specific Antigen (PSA) levels to assess treatment efficacy.
  • Protect skin from excessive sunlight by wearing sunscreen and protective clothing.
  • Blood glucose levels should be monitored, especially in diabetic patients.
  • Pregnancy & Lactation:
    • Contraindicated in women.
    • Effective contraception is required during treatment for both men and women to prevent pregnancy.
✔️ Storage:

Store it in a cool, dry place below 30°C, away from light and moisture. Keep it out of reach of children and pets.

Frequently Asked Questions (FAQ)

Bicalon is prescribed for the treatment of prostate cancer, particularly in advanced stages. It helps reduce or prevent the growth of prostate cancer cells by blocking male hormones like testosterone.

Yes, it can be taken with or without food. However, try to take it at the same time every day for consistency.

Contact your doctor or go to the nearest hospital immediately. There is no specific antidote, so treatment is supportive and symptom-based.

Avoid excessive sun exposure. Limit alcohol consumption. Avoid medications that interact with Bicalutamide (consult your doctor for a list).

No, it is not a traditional chemotherapy drug. It is an anti-androgen medication that works by blocking male hormones, which are essential for the growth of prostate cancer cells.

Abdominal pain is a common side effect. If it is severe or persistent, contact your doctor for further evaluation.

The duration of treatment varies depending on your condition and response to therapy. It may range from several months to years. Follow your doctor’s recommendations and do not stop taking the medication without medical advice.

Yes, hair loss is a known side effect of this medication. While it is generally mild to moderate, consult your doctor if it becomes bothersome.

Diarrhea is a possible side effect. If it occurs and persists, consult your doctor. Avoid taking over-the-counter antidiarrheal medications without medical advice.

If you miss a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one. Do not take a double dose to make up for a missed dose.

Seek immediate medical attention, as these may be symptoms of a serious lung or heart-related problem.

Common side effects include: Weakness Skin rash Breast tenderness or swelling in men Hot flushes Nausea Hair loss Constipation Weight gain Anemia Decreased libido Dizziness Most of these side effects resolve over time, but consult your doctor if they persist or worsen.

Bicalon should be used cautiously in diabetic patients, as it can increase blood sugar levels. Regular monitoring of blood glucose is recommended during treatment.

Avoid Sun Exposure: This medication may make your skin more sensitive to sunlight. Use sunscreen and protective clothing when outdoors. Avoid Certain Medications: Inform your doctor if you’re taking drugs like terfenadine, astemizole, or cisapride, as these can interact with Bicalutamide. Inform Your Doctor: Share your full medical history, especially if you have diabetes, liver problems, or heart rhythm disorders.

Yes, Bicalon may cause temporary or permanent infertility in men. If you plan to father a child, consult your doctor before starting treatment.

It is important to inform your doctor about all medications you are taking, as some may interact with Bicalon. Do not combine medications without medical advice.

No, Bicalon 50mg Tablet is not recommended for use in women or children.

Bicalon 50mg Tablet contains Bicalutamide, an anti-androgen drug that inhibits the effects of male hormones (androgens) like testosterone, thereby shrinking prostate tumors and slowing cancer progression.
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⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

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