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Bicalon 50mg Tablet 14pcs
- Bicalon/Bicalutamide is a non-steroidal androgen receptor inhibitor that blocks androgen action by binding to cytosol androgen receptors in target tissues. Prostate carcinoma, being androgen-sensitive, responds to treatments that inhibit androgen effects or remove androgen sources.
- Used in combination with a luteinizing hormone-releasing hormone (LHRH) analog for the treatment of Stage D2 metastatic carcinoma of the prostate.
- রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন (Take under the guidance of a registered physician).
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✅ Description:
Bicalutamide
- Treatment of prostate cancer, particularly advanced or metastatic stages (e.g., Stage D2 carcinoma).
- May also treat other androgen-dependent conditions as determined by a physician.
- Contraindicated in pregnancy as it can cause fetal harm.
- Not indicated for use in females.
- Monitor PT/INR when used with coumarin anticoagulants.
- Gynecomastia and breast pain: Reported with higher doses (150 mg).
- Blood glucose monitoring: Consider patients using Bicalon with LHRH agonists due to potential reduction in glucose tolerance.
- Regular monitoring is recommended; assess clinical progression if PSA levels increase.
Safety Advices
Alcohol
UNSAFE
Avoid alcohol while on Bicalon 50, as it can increase the risk of liver problems and interfere with the medication's effectiveness.
Pregnancy
UNSAFE
Bicalon 50 is contraindicated in pregnant women as it is not approved for use in women. Please consult a doctor if you are pregnant or planning for pregnancy.
UNSAFE
Bicalon 50 is contraindicated in breastfeeding women as it is not approved for use in women. Please consult a doctor if you are breastfeeding.
Breastfeeding
CONSULT YOUR DOCTOR
Bicalon 50 may cause drowsiness in some people. Therefore, avoid driving if you are drowsy after taking Bicalon 50
CONSULT YOUR DOCTOR
Take Bicalon 50 with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ How does Bicalon 50 work?
- Bicalutamide is a non-steroidal androgen receptor inhibitor.
- It blocks the effects of male hormones (androgens), such as testosterone, by binding to androgen receptors, which prevents the growth of prostate cancer cells.
✔️ Dosage and Administration of Bicalon 50
- Adult Dose:
- Recommended Dose: One 50 mg tablet daily (morning or evening), with or without food.
- Pediatric Use:
- Safety and effectiveness have not been established in pediatric patients.
- Hepatic Impairment:
- Use with caution in patients with moderate-to-severe hepatic impairment as the drug is extensively metabolized by the liver.
✔️ Adverse effects (seen in more than 10% of patients):
Hot flashes, pain (general, back, pelvic, abdominal), asthenia, constipation, infection, nausea, peripheral edema, dyspnea, diarrhea, hematuria, nocturia, anemia.
✔️ Quick Suggestions:
- Take at the same time daily for consistency.
- Avoid stopping the medication without consulting your doctor.
- Watch for signs of liver damage or severe side effects and report them immediately.
- Attend all follow-up appointments for blood tests to monitor liver function and PSA levels.
- Practice effective contraception during treatment.
✔️ Overdose Effects of Bicalon 50
- Clinical trials with doses up to 200 mg daily were well-tolerated.
- No specific antidote; symptomatic treatment is recommended in case of overdose.
✔️ Serious Side Effects Requiring Immediate Attention
- Liver Damage: Yellowing of skin/eyes, dark urine, stomach pain.
- Anemia: Symptoms include fatigue and shortness of breath.
- Skin sensitivity to sunlight: Avoid excessive exposure and use sunscreen.
✔️ Drug Interactions
- Coumarin Anticoagulants: Bicalutamide enhances the effects of anticoagulants such as warfarin.
- Monitor Prothrombin Time (PT) and INR regularly.
✔️ Contraindications
- Hypersensitivity to Bicalutamide or its components.
- Not indicated for women, children, or during pregnancy and lactation.
✔️ Precautions & Warnings
- Regular liver function tests are advised during long-term therapy.
- Monitor Prostate-Specific Antigen (PSA) levels to assess treatment efficacy.
- Protect skin from excessive sunlight by wearing sunscreen and protective clothing.
- Blood glucose levels should be monitored, especially in diabetic patients.
- Pregnancy & Lactation:
- Contraindicated in women.
- Effective contraception is required during treatment for both men and women to prevent pregnancy.
✔️ Storage:
Store it in a cool, dry place below 30°C, away from light and moisture. Keep it out of reach of children and pets.
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lab tests, medicines, all possible side effects, drug interactions,
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and discuss all your queries related to any disease or medicine. We
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