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GOL Sugar Free Oral Solution 100ml
GOL is used in adults and children over the age of 12 for the effective relief of constipation and the treatment of chronic constipation. It is also effective for resolving fecal impaction, which is defined as severe constipation with fecal buildup in the rectum and colon.
Sodium chloride helps restore electrolyte balance and water distribution. Potassium chloride plays a crucial role in nerve conduction, muscle contraction, and maintaining normal kidney function. Sodium bicarbonate raises blood and urinary pH by neutralizing acidity, and Polyethylene Glycol increases stool water content, promoting easier bowel movements.
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✅ Description:
Each 25 mL concentrated oral solution contains:
- Polyethylene Glycol 3350: 13.125 gm
- Sodium Chloride: 350.7 mg
- Sodium Bicarbonate: 178.5 mg
- Potassium Chloride: 46.6 mg
Each sachet (powder for suspension) contains:
- Polyethylene Glycol 3350: 13.125 gm
- Sodium Chloride: 350.7 mg
- Sodium Bicarbonate: 178.5 mg
- Potassium Chloride BP: 46.6 mg
✔️ Indications: GOL
Polyethylene glycol (PEG) works as an osmotic agent in the gut, inducing a laxative effect. It increases stool volume, stimulating colon motility through neuromuscular pathways. This improves the movement of softened stools, facilitating defecation. The electrolytes in the formulation are exchanged with serum electrolytes across the intestinal mucosa and excreted without causing an imbalance in sodium, potassium, or water. PEG remains unchanged in the gastrointestinal tract and is largely unabsorbed.
✔️ Generally well tolerated, but some side effects may include:
- Allergic reactions
- Electrolyte disturbances, such as hyperkalemia (high potassium) and hypokalemia (low potassium)
- Abdominal pain, diarrhea, headache, peripheral edema (swelling)
✔️ Dosage & Administration of Gol
For adults and children aged 12 and older:
- Constipation: Take 1 sachet daily, which may be increased to 2-3 sachets daily if necessary.
- Fecal Impaction: Take 8 sachets daily, consumed within 6 hours. Treatment for fecal impaction should not exceed 3 days.
For patients with renal insufficiency, no dosage adjustment is required.
✔️ Oral Solution:
- Constipation: Take 25 mL of the oral solution added to 100 mL of water once daily. The dose may be increased to 2-3 doses per day as needed.
- Fecal Impaction: Take 8 doses of 25 mL daily (each mixed with 100 mL of water). The treatment should not exceed 3 days.
Unused diluted solution should be discarded after 24 hours.
✔️ Directions for Use: GOL
- Dissolve one sachet in 125 mL of water.
- For fecal impaction, dissolve 8 sachets in 1 liter of water. Store the solution in the fridge and discard any unused solution within 6 hours.
✔️ Interactions of GOL
The absorption of other medicines may be temporarily reduced when taken with this solution. There have been isolated reports of decreased efficacy with certain medications, such as anti-epileptics.
✔️ Contraindications
- Intestinal perforation or obstruction due to structural or functional issues in the gut, ileus, or severe inflammatory conditions like Crohn’s disease, ulcerative colitis, and toxic megacolon.
- Hypersensitivity to the active ingredients.
✔️ Pregnancy & Lactation
- Pregnancy: There are no expected harmful effects during pregnancy, as systemic absorption of Polyethylene Glycol is minimal. It can be used during pregnancy.
- Lactation: The systemic exposure to Polyethylene Glycol during breastfeeding is negligible, and no effects on the breastfed infant are expected. It can be used during breastfeeding.
✔️ Precautions & Warnings
- For patients with impaired cardiovascular function, the dose should be divided to ensure no more than two sachets are taken per hour.
- If symptoms suggest fluid or electrolyte disturbances (e.g., edema, shortness of breath, fatigue, dehydration, or cardiac failure), stop the medication immediately and treat accordingly.
- Prolonged use of laxatives is undesirable and can lead to dependency.
✔️ Storage Conditions
Store below 30°C, protected from light. Do not refrigerate.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
