Mirtaz 15mg Tablet

✔️ Uses of Mirtaz 15mg Tablet

• Treats Depression in adults

✔️ How does Mirtaz 15mg Tablet work?

This medicine works by affecting the communication process between nerve cells and restoring the chemical balance in the brain.

✔️ Side Effects of Mirtaz 15mg Tablet

• Constipation
• Increased Appetite
• Weight Gain
• Hypertension
• Edema (Swelling)
• Dizziness
• Abnormal Dreams
• Abnormal Thoughts
• Confusion
• Vomiting
• Anorexia
• Back Pain
• Arthralgia
• Tremor
• Weakness

✔️ Quick Suggestions:

• Mirtazapine starts to work more quickly than other antidepressants.
• Avoid driving or operating dangerous machinery as it may decrease alertness.
• Avoid consuming alcohol when taking Mirtazapine, as it may cause excessive drowsiness and calmness.
• If your doctor asks you to stop Mirtazapine, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
• Notify your doctor immediately if you develop a sore throat or fever or stomatitis during treatment with Mirtazapine.

✔️ Indication

Mirtaz 15mg Tablet is a Tetracyclic antidepressant used to treat severe depression symptoms such as sadness, loss of interest, impatience, and sleeplessness. It is a prescription-only medication that increases synthetic messengers in the brain to provide a calming effect and alleviate depression. The full effect may take up to a month to appear, with some benefits possibly seen in one to fourteen days.

✔️ Pharmacology

Mirtazapine is a piperazinoazepine tetracyclic antidepressant that works by enhancing noradrenergic and serotonergic activity. It does this by blocking central presynaptic adrenergic alpha 2 receptors. This action increases the levels of norepinephrine and serotonin in the brain, which helps in treating depression and related mood disorders.

✔️ Dosage & Administration of Mirtaz 15mg Tablet

• Adult dose: The recommended starting dose for Mirtazapine tablets is 15 mg/day, taken in the evening or before sleep. The effective dose range is generally 15 to 45 mg/day, and dose adjustments should be made at intervals of 1 to 2 weeks to allow time for the therapeutic response.
• Use in children: Mirtazapine is not recommended for use in children.
• Missed Dose: If you miss a dose, take it as soon as you remember, unless it's close to the time for the next dose. In that case, skip the missed dose and take the next dose at the regular time. Do not take a double dose.
• Overdosage: If you or anyone else accidentally takes more than the prescribed dose of Mirtazapine, seek medical attention immediately. Symptoms of overdose may include severe drowsiness, fast heart rate, fainting, or disorientation.

✔️ Interaction

When taking multiple medications, combining them with certain foods or alcohol can lead to drug interactions. It's essential to be cautious and aware of potential interactions to avoid adverse effects.

• Alcohol: Limit or avoid alcohol intake while on this medication. It can cause additional sedation and impair mental alertness, such as driving or operating machinery.
• Lab Tests: No specific information on interactions with lab tests is available.
• CYP1A2, 2C9, 2D6, and 3A3/4 Enzyme Substrate: Serious or fatal reactions can occur when this medicine is given with or within 14 days of a monoamine oxidase inhibitor.
• Food: No specific information on interactions with food is available.
• Neutropenia/Agranulocytosis: If signs and symptoms of neutropenia/agranulocytosis occur, discontinue the medication immediately.
• Sedation and CNS Depressants: The sedative effects may be increased when combined with other CNS depressants or ethanol.
• Worsening Psychosis: Mirtazapine may worsen psychosis in some patients or trigger mania or hypomania in individuals with bipolar disorder.
• Orthostatic Hypotension and Anticholinergic Effects: The risk of these effects is relatively low compared to other antidepressants.
• Sexual Dysfunction: The incidence of sexual dysfunction with mirtazapine is generally lower than with SSRIs.

Always follow your doctor's instructions and report any side effects or concerns promptly to ensure safe and effective use of the medication.

✔️ Contraindications

Mirtazapine Tablets are contraindicated in patients with a known hypersensitivity to mirtazapine or to any of the excipients.

✔️ Pregnancy & Lactation

Category-C Pregnancy. Patients should be encouraged to tell their doctor if they get pregnant or plan to become pregnant while taking Mirtazapine. If a patient is nursing a newborn, they should tell their doctor.

✔️ Precautions & Warnings

• Epilepsy or history of seizures: Avoid completely, especially in unstable cases.
• Hepatic or renal impairment: Use with caution in patients with liver or kidney problems.
• Cardiac disorders: Use with caution in patients with conduction disturbances, angina pectoris, or recent heart attack.
• Hypotension: Be cautious in patients with low blood pressure.
• Diabetes mellitus (DM): Use with caution in diabetic patients.
• Psychoses or history of bipolar disorder: Use with caution in patients with a history of psychiatric conditions.
• Jaundice: Discontinue treatment if jaundice develops.
• Micturition disturbances: Be cautious in patients with urinary issues.
• Angle-closure glaucoma and raised intraocular pressure: Use with caution in patients with these eye conditions.
• Bone marrow depression: Monitor for signs of bone marrow depression.
• Suicidal tendency: Monitor patients for signs of suicidal thoughts or behavior.
• Abrupt withdrawal: Avoid sudden discontinuation of the medication.
• Impairment of activities: This may impair the ability to drive or operate machinery.
• Pregnancy and lactation: Avoid use during pregnancy and lactation.
• Elderly: Use with caution in elderly patients.
• Lactation: Avoid use in breastfeeding women.

✔️ Storage Conditions

Keep this medicine tightly packed in the packet or container it came in. Close the lid tightly after use. It must be stored according to the package or label's directions. Any unused drug must be disposed off with caution. Make sure it isn't eaten by pets, children, or other people.