Bolardi 500mg 6pcs Capsule

Uses of Saccharomyces Boulardii

Diarrhea

How does Bolardi work?

Saccharomyces boulardii is a dried form of yeast called probiotics that acts as a friendly organism that helps to fight against disease-causing organisms in the gut such as bacteria and yeast.

Side Effects of Bolardi

• Gas
• Bloating
• Constipation

Quick Suggestions:

• Avoid eating foods such as milk, dairy products, spicy foods, processed foods, caffeinated and carbonated drinks.
• Eat fiber-rich food such as whole grains, lentils, beans, broccoli, and peas.
• Wash your hands thoroughly before eating while preparing or serving food.

Indications:

• Diarrhea associated with antibiotics
• Traveler's diarrhea
• Recurring intestinal disease caused by Clostridium difficile
• Side effects of treatment for Helicobacter pylori
• Symptoms of acute diarrhea
• Diarrhea in infants
• Crohn's disease
• Ulcerative colitis and IBS

Pharmacology

Saccharomyces boulardii is a probiotic yeast that survives stomach acid to colonize the intestinal tract. It acts as a temporary flora to protect the beneficial organisms in the intestine. It helps re-establish the microflora, supporting healthy immunity, digestion, and gut health. It shows the following actions:

• Anti-toxin activity: Neutralizes bacterial toxins, including those from Clostridium difficile.
• Anti-microbial: Adheres to pathogens, decreasing their adhesion to the intestinal wall and invasion of enterocytes.
• Enzymatic activity: Increases enzymatic activities (lactase, alpha-glucosidase, alkaline phosphatase) and the production of intestinal polyamines, enhancing brush border enzymes.
• Immune Enhancement: Stimulates the immune system along the GI lining, increasing the protective antibody IgA.
• Anti-inflammatory: Decreases pro-inflammatory cytokines.

Dosage & Administration of Bolardi

Adults:

• Diarrhea associated with antibiotics: 250-500 mg two to four times a day.
• Diarrhea caused by Clostridium difficile: 1 gram daily for 4 weeks along with antibiotic treatment.
• Acute diarrhea: 250 mg twice a day for 5 days.
• Crohn's disease: 250 mg three times daily for up to 9 weeks.
• Ulcerative colitis: 250 mg three times daily.
• Helicobacter pylori infections: 250-500 mg twice daily in addition to usual treatment.
• Irritable bowel syndrome (IBS): 250 mg twice daily.
• Traveler's diarrhea: 250 mg per day.

Children:

• Acute diarrhea (over three months): 250 mg twice daily for five days.
• Acute diarrhea (under three months): 125 mg twice daily for five days.

Take as directed by a registered physician.

Interaction

Drug Interactions:

• Drug-Drug Interactions: Saccharomyces Boulardii may interact with antifungal medications such as fluconazole, caspofungin, itraconazole, and amphotericin.
• Drug-Food Interactions: No interactions with food have been found or established.
• Drug-Disease Interactions: Notify your doctor if you have a weakened immune system or a yeast allergy.

Contraindications

Contraindicated in patients with a history of hypersensitivity to Saccharomyces boulardii or any other components of this product.

Pregnancy & Lactation

There is no available information about the safety of taking Saccharomyces boulardii during pregnancy and lactation.

Precautions & Warnings

Avoid Saccharomyces Boulardii if you are allergic to any of its components. Notify your doctor if you have a weakened immune system, yeast allergy, or if you are taking antifungal medications. Consult your doctor if you are pregnant or breastfeeding. Saccharomyces Boulardii can be administered to children under medical supervision.

Storage Conditions:

Store below 25° C, away from direct sunlight and moisture. Keep out of reach of children.