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Ace 125mg Suppository 1 pc
Ace 125 /Paracetamol 125mg Suppository is used to treat:
- Fever
- Mild to moderate pain (e.g., headache, toothache, body ache, postoperative pain)
- Osteoarthritis and rheumatoid arthritis
- Chronic low back pain and neuropathic pain
- Renal stone pain and migraine
- Pain relief after vaccination (post-immunization fever in infants)
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✅ Description:
- Paracetamol (active ingredient) blocks pain signals and reduces fever by inhibiting prostaglandin synthesis in the brain.
- It also lowers body temperature by acting on the hypothalamic heat-regulating center.
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✔️ Dosage & Administration of Ace 125mg Suppository
Rectal Suppository:
- Children 3 months - <1 year: 60-125 mg
- Children 1-<5 years: 125-250 mg
- Children 5-12 years: 250-500 mg
- Children over 12 years & Adults: 500 mg-1 g every 4-6 hours (max 4 g daily)
- Post-immunization fever (2-3 months old): 60 mg; a second dose may be given after 4-6 hours if needed
✔️ Side Effects
- Common: No common side effects when used correctly.
- Rare but serious:
- Blood disorders (thrombocytopenia, leucopenia, neutropenia)
- Liver toxicity and acute kidney damage (with overdose or prolonged use)
- Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis)
✔️ Drug Interactions
- Reduces the effectiveness of anticonvulsants (phenytoin, carbamazepine).
- May enhance the blood-thinning effects of warfarin (increasing bleeding risk).
- Faster absorption with metoclopramide and domperidone.
- Increased risk of liver damage with alcohol.
- Reduced absorption with colestyramine (avoid within 1 hour of taking Ace 125).
✔️ Contraindications
- Hypersensitivity to paracetamol or any other ingredient.
✔️ Precautions & Warnings
- Liver & kidney impairment – Dose adjustment may be needed.
- Chronic alcoholism – Increased risk of liver damage.
- G6PD deficiency, severe malnutrition, hypovolemia – Use with caution.
- Pregnancy & lactation – Generally safe, but consult a doctor.
- Long-term use – Requires regular monitoring of liver function and blood components.
✔️ Storage
- Store in a cool, dry place below 30°C.
- Keep out of reach of children.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
