Infud 1% Cream

✔️ Uses of Infud 1% Cream

• Athlete's foot
• Jock itch
• Ringworm infection

✔️ How does Infud 1% Cream work?

Terbicip 1 % Spray works by stopping the production of a chemical known as ergosterol, which is responsible for forming the fungal cell membrane (the protective covering of the fungi). Thus, it kills the fungi and stops the spread of infections.

✔️ Side Effects of Infud 1% Cream

Common side effects of Infud 1% Cream may include skin peeling and skin itching. Uncommon side effects can involve skin lesions, scabs, skin color changes, skin redness, and application site reactions like pain, irritation, or a burning sensation. Rare side effects might encompass eye irritation, skin dryness, and skin inflammation.

If you experience any of the following severe side effects, stop using Infud 1% Creamand promptly contact your doctor:

1. A severe skin rash with raised lumps, hives, and blistering.
2. Signs of an allergic reaction, such as skin rash, itching, and swelling of the face, mouth, tongue, and throat, leading to difficulty in breathing.

✔️ Quick Suggestions:

• Terbinafine helps treat fungal infections of the skin and nails.
• Do not skip any doses and finish the full course of treatment even if you feel better.
• Treatment may be needed for 2 to 6 weeks for skin infections and 6 weeks to 6 months for nail infections.
• It can make your skin more sensitive to the sun. Use broad-spectrum sunscreen and protective clothing when outdoors.
• Your doctor may monitor your liver function regularly during treatment. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
• Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

✔️ Indications:

Fungal nail infections, also known as onychomycosis, are frequently occurring infections that affect toenails and fingernails. These infections are caused by various types of fungi found in the environment. These fungal invaders gain access to the nails through small cracks in the nail or the surrounding skin, leading to infection. Symptoms of fungal nail infections include thickened or discolored (brown, yellow, or white) nails that are more susceptible to breakage. Typically, these infections are not painful unless they become severe. It's worth noting that fungal infections are more commonly found in toenails than in fingernails.

Tinea capitis, commonly referred to as scalp ringworm, is a fungal infection that affects the scalp, involving both the hair and the skin. This condition is contagious, and its symptoms include dry, itchy, and scaly patches on the scalp, along with hair loss and redness. The name "ringworm" arises from the circular or ring-shaped appearance of the affected areas. Tinea capitis primarily affects children between the ages of 3 and 7 years.

✔️ Pharmacology

Terbinafine is an antifungal Allylamine that works by inhibiting the formation of Ergosterol, a vital component of fungal cell membranes. This inhibition occurs by blocking the Squalene Epoxidase enzyme. This process results in an accumulation of high amounts of Squalene, which, rather than Ergosterol deficiency, enhances membrane permeability, ultimately causing fungal cell death. Depending on the medication concentration and the fungal species, Terbinafine hydrochloride can be fungicidal, although the clinical significance of in vitro data remains unclear. In both in vitro and clinical infections, Terbinafine has demonstrated effectiveness against most strains of Trichophyton Mentagrophyte and Trichophyton rubrum.

✔️ Dosage & Administration of Infud 1% Cream

• Terbinafine cream is typically applied once or twice daily. The affected areas should be cleaned and dried before applying the cream. A thin layer of the cream is applied to the affected skin and the surrounding area and gently massaged in. For intertriginous infections (submammary, interdigital, intergluteal, inguinal), the application may be covered with a gauze strip at night. The expected treatment durations are as follows:
  • 1 to 2 weeks for tinea corporis and cruris
  • 1 week for Tinea Pedis
  • 2 weeks for cutaneous candidiasis
  • 2 weeks for Pityriasis versicolor Clinical symptoms typically improve within a few days, but discontinuing treatment prematurely or not adhering to a consistent treatment regimen may increase the risk of recurrence. If there is no improvement after two weeks, the diagnosis should be confirmed.

✔️ Interaction

Terbinafine, like many medications, has the potential to interact with other drugs, foods, and medical conditions. Here are some of the important interactions to be aware of:

Drug-Drug Interaction: Terbinafine may interact with various drugs, including:

• Drugs used to treat stomach ulcers, like cimetidine.
• Antibiotics such as rifampicin.
• Antifungal medications like fluconazole.
• Medications for high blood pressure, such as metoprolol.
• Antidepressants like duloxetine and desipramine.
• Opioid painkillers like codeine and tramadol.
• Blood thinners such as warfarin.
• Medications related to heart conditions, like amiodarone.
• Immunosuppressants like ciclosporin.

Drug-Food Interaction: Terbinafine may interact with caffeine. It is advisable to avoid foods containing caffeine, including chocolate, cocoa beans, tea, coffee, cola, and energy drinks while taking terbinafine. Consuming caffeine along with terbinafine could increase the adverse effects of caffeine.

Drug-Disease Interaction: It's important to inform your doctor before taking terbinafine if you have certain medical conditions, including:

• Lupus, which is an autoimmune disease.
• A weakened immune system.
• Kidney problems.
• Liver problems.

✔️ Contraindications

Terbinafine cream should not be used by individuals with hypersensitivity to terbinafine.

✔️ Pregnancy & Lactation

• Terbinafine cream has not shown adverse effects on fetal toxicity and fertility in animal studies. Clinical experience in pregnant women is limited, so the use of terbinafine during pregnancy should be considered only if the potential benefits outweigh the potential risks. Terbinafine is excreted in breast milk, so breastfeeding mothers should avoid terbinafine medication.

✔️ Precautions & Warnings

• Allergy to Terbinafine: If you are allergic to terbinafine, avoid using Terbinafine. Allergic reactions can vary in severity, and it's essential to steer clear of any substances that trigger an allergic response in your body.
• Pregnancy and Nursing: If you are pregnant or a nursing mother, consult with your doctor before using Terbinafine. It's important to assess the potential risks and benefits, especially during pregnancy and breastfeeding when the well-being of both the mother and child is a concern.
• Sun Exposure: Terbinafine can make your skin more sensitive to sunlight. To avoid skin damage from sunburn, limit sun exposure and protect your skin by wearing suitable clothing and using sunscreen when going outdoors.
• Underlying Medical Conditions: If you have certain health conditions, such as lupus (an autoimmune disease), a weakened immune system, kidney problems, or liver problems, inform your doctor before starting Terbinafine. These conditions can impact how your body reacts to the medication.
• Mental Health: If you experience symptoms of depression, like feeling worthless, sadness, loss of interest or energy in daily activities, mood changes, restlessness, or disruptions in sleep patterns while taking Terbinafine, inform your doctor promptly. Your mental well-being is essential, and your healthcare provider can offer appropriate guidance.

✔️ Storage Conditions

Terbinafine should be protected from light and stored in a cool, dry area below 30°C.