Terbinafine is used to treat fungal infections like athlete's foot (itchy, scaly, and white patches between the toes), jock itch (red, itchy, and ring-shaped rashes in the groin, the area where the upper thigh meets the lowest part of the stomach), ringworm (red, itchy, and circular-shaped rashes with clear skin in the middle affecting the skin, scalp, or nails), and nail infections. This medicine works by killing the fungi by damaging their cell membrane (protective covering) and making them weaker. Thus, it prevents the spread of fungal infections.
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The interaction of alcohol with Xfin 250mg Tablet is unknown. Please consult a doctor before consuming alcohol with Xfin 250mg Tablet.
Xfin 250mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects on the developing baby; however, there are limited human studies.
Xfin 250mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Xfin 250mg Tablet may cause dizziness. Therefore, drive only if you are alert after taking Xfin 250mg Tablet
Xfin 250mg Tablet should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
Xfin 250mg Tablet is not recommended for use in patients with an active or a previous history of liver problems. Therefore, consult your doctor before taking it.
Antifungal medicine Xfin 250mg Tablet is available. It successfully manages fungus infections inside the body. By preventing the cell's ability to produce specific molecules (ergosterol) necessary for life, it damages the fungal cell membrane. As a result, it prevents the fungal cell from proliferating, stopping the infection from spreading further.
Xfin 250mg Tablet is used to treat a variety of skin and nail fungal infections, including ringworm. It kills the fungus that causes the infection.
Terbinafine, an Allylamine antifungal, inhibits Ergosterol biosynthesis (an essential component of the fungal cell membrane) by inhibiting Squalene Epoxidase. This causes fungal cell death due to increased membrane permeability caused by the accumulation of high concentrations of Squalene, rather than Ergosterol deficiency. Terbinafine Hydrochloride may be fungicidal depending on the drug concentration and the fungal species tested in vitro.
The clinical significance of in vitro data, on the other hand, is unknown. Terbinafine has been shown in vitro and in clinical infections to be effective against most strains of the following microorganisms: Trichophyton mentagrophyte and Trichophyton rubrum.
Relief of the clinical symptoms usually occurs within a few days. Irregular use or premature discontinuation of treatment carries the risk of recurrence. If there are no signs of improvement after two weeks, the diagnosis should be verified.
According to research, terbinafine inhibits the CYP450 2D6 isozyme in vivo. Among the drugs primarily processed by the CYP450 2D6 isozyme are tricyclic antidepressants, selective serotonin reuptake inhibitors, beta-blockers, antiarrhythmics class 1C (e.g., flecainide and propafenone), and monoamine oxidase inhibitors type B. Terbinafine should be administered with caution, and the dose of the 2D6-metabolized medication may need to be reduced.
Terbinafine tablets and cream are not recommended for people who are hypersensitive to terbinafine.
Terbinafine cream has been shown to have no negative effects on fetal toxicity and fertility in animals. There is no clinical experience with Terbinafine in pregnant women; consequently, terbinafine should not be used unless the possible benefits outweigh the potential risks. Terbinafine is secreted in breast milk, so mothers who are breastfeeding should avoid terbinafine medication.
Protect from light and moisture by storing in a cool, dry place below 25°C. Keep out of children's reach.
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