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Indications of Delanzo 30mg Capsule
A medication called Delanzo 30mg lowers the amount of acid your stomach produces. It is used to treat illnesses of the stomach and intestine caused by excessive acid production, including heartburn, acid reflux, peptic ulcer disease, and various other conditions of the stomach. Additionally, Delanzo 30mg is used to avoid the acidity and stomach ulcers that may result from using painkillers for an extended period of time.
Pharmacology
A proton pump inhibitor (PPI), such as the sustained-release capsule of dexlansoprazole, prevents the secretion of gastric acid by specifically blocking (H + / K +) ATPase in gastric parietal cells. Dexlansoprazole stops the final stage of acid generation by only affecting the proton pump. It is lansoprazole's enantiomer (a racemic mixture of R and the enantiomer). In an oral pill, dexlansoprazole is offered in a dual delayed release (DDR) format. Two different enteric-coated granule types with various pH-dependent dissolving characteristics are mixed together in the capsule. The peak plasma concentration-time profiles for dexlansoprazole's dual delayed-release formulation differ; the first peak occurs 1 to 2 hours after treatment, and the second peak occurs 4 to 5 hours later. Dexlansoprazole's typical Cmax and AUC values after oral delivery rise roughly in proportion to the dose. The liver substantially metabolizes dexlansoprazole, which is then eliminated in the urine.
Dosage & Administration of Delanzo 30mg
Dosage guidelines for dexlansoprazole:
Heartburn treatment and maintenance of healed erosive esophagitis: 30 mg Symptomatic, non-erosive GERD: 30 mg once daily every day for four weeks.
60 mg for the treatment of erosive esophagitis every day for as long as 8 weeks
You can take dexlansoprazole without consideration of diet. It ought to be consumed entirely.
Instead, the following instructions can be used to deliver Dexlansoprazole capsules:
Interaction
With diuretics and digoxin, there is an increased risk of hypomagnesemia. Erlotinib, masitinib, and lapatinib plasma concentrations may be reduced. Itraconazole and ketoconazole bioavailability may be reduced. Cilostazol and methotrexate plasma concentrations may be increased. Antacids and sucralfate reduce bioavailability. Possibly fatal: Rilpivirine and atazanavir serum levels and pharmacological effects may be reduced.
Contraindications
Patients who are known to be allergic to any component of the preparation should not use dexlansoprazole.
Side Effects of Delanzo 30mg
Pregnancy and Lactation
Pregnancy category B. There are no adequate and well-controlled studies on the use of dexlansoprazole in pregnant women. There are no adequate and well-controlled studies on the use of dexlansoprazole in breastfeeding mothers.
Precaution and Warning
Impairment of the liver. Gastric cancer should be ruled out. Lactation and pregnancy Summary of Lactation Risks There is no information on the presence of dexlansoprazole in human milk, its effects on breastfed infants, or its effects on milk production; however, lansoprazole and its metabolites are present in rat milk; the developmental and health benefits of breastfeeding should be considered alongside the mother's clinical need for therapy and potential adverse effects on the breastfed child from therapy or the underlying maternal condition.
Storage Conditions
Store below 30°C temperature & in a dry place, protected from light. Keep all medicines out of reach of children.
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