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Imax 20mg Capsule 1 Strip
Esomeprazole, the active component of iMAX, is a proton pump inhibitor (PPI) that works by selectively blocking the H⁺/K⁺-ATPase enzyme in gastric parietal cells, thus reducing stomach acid production. As the S-isomer of omeprazole, esomeprazole offers more effective acid suppression than its racemic counterpart.
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✅ Description:
iMAX is used for:
- Long-term relief from persistent heartburn and GERD-related symptoms
- Healing and maintenance of healing in erosive esophagitis
- Eradication of Helicobacter pylori when used with amoxicillin and clarithromycin in duodenal ulcer cases
- Managing Zollinger-Ellison Syndrome
- Treating acid-related indigestion
- Healing duodenal and gastric ulcer
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Side Effects of Imax 20
- Headache
- Diarrhea
- Nausea
- Flatulence
- Abdominal discomfort
- Constipation
- Dry mouth
✔️ Dosage & Administration of Imax 20
Oral (Capsules/Tablets):
- Erosive Esophagitis: 20–40 mg once daily for 4–8 weeks (extendable if unhealed)
- Maintenance of Healing: 20 mg once daily (up to 6 months)
- GERD Symptoms: 20 mg daily for 4 weeks (extendable if unresolved)
- H. pylori Eradication: 40 mg once daily + Amoxicillin 1000 mg BID + Clarithromycin 500 mg BID for 10 days
- Zollinger-Ellison Syndrome: 20–80 mg daily, adjusted individually
- Acid Dyspepsia: 20–40 mg daily for 2–4 weeks
- Duodenal Ulcer: 20 mg daily for 2–4 weeks
- Gastric Ulcer: 20–40 mg daily for 4–8 weeks
- Children: Not established.
- Elderly: No major differences observed, but individual sensitivity may vary.
- Liver Impairment: In severe hepatic insufficiency, limit dose to 20 mg/day.
- Kidney Impairment: No dose adjustment needed as <1% is excreted unchanged.
Capsules/Tablets: Swallow whole, 1 hour before meals.
✔️ Drug Interactions
- iMAX is metabolized mainly via CYP2C19 and CYP3A4.
- Minimal interaction with drugs metabolized by other CYP enzymes.
- Co-admin with diazepam may increase diazepam levels.
- Reduced absorption of drugs dependent on acidic pH (e.g., ketoconazole, iron salts, digoxin).
- Safe to use with oral contraceptives, phenytoin, quinidine, and antibiotics like amoxicillin and clarithromycin.
✔️ Contraindications
- Known hypersensitivity to esomeprazole or any capsule component.
- No difference in side effects seen between short-term and long-term use (up to 12 months).
✔️ Use During Pregnancy & Lactation
- Limited human data; animal studies show no teratogenic effects.
- Unknown if excreted in breast milk—discontinue breastfeeding if necessary.
✔️ Precautions
- Rule out gastric malignancy before starting iMAX.
- Can be taken with antacids.
- For patients unable to swallow capsules: contents can be sprinkled on soft applesauce and swallowed immediately (no chewing or storage).
✔️ Storage
- Store in a cool, dry place below 30°C.
- Protect from light and moisture.
- Keep out of children's reach.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
