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Imax 20mg Capsule 1 Strip
Esomeprazole, the active component of iMAX, is a proton pump inhibitor (PPI) that works by selectively blocking the H⁺/K⁺-ATPase enzyme in gastric parietal cells, thus reducing stomach acid production. As the S-isomer of omeprazole, esomeprazole offers more effective acid suppression than its racemic counterpart.
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✅ Description:
iMAX is used for:
- Long-term relief from persistent heartburn and GERD-related symptoms
- Healing and maintenance of healing in erosive esophagitis
- Eradication of Helicobacter pylori when used with amoxicillin and clarithromycin in duodenal ulcer cases
- Managing Zollinger-Ellison Syndrome
- Treating acid-related indigestion
- Healing duodenal and gastric ulcer
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Side Effects of Imax 20
- Headache
- Diarrhea
- Nausea
- Flatulence
- Abdominal discomfort
- Constipation
- Dry mouth
✔️ Dosage & Administration of Imax 20
Oral (Capsules/Tablets):
- Erosive Esophagitis: 20–40 mg once daily for 4–8 weeks (extendable if unhealed)
- Maintenance of Healing: 20 mg once daily (up to 6 months)
- GERD Symptoms: 20 mg daily for 4 weeks (extendable if unresolved)
- H. pylori Eradication: 40 mg once daily + Amoxicillin 1000 mg BID + Clarithromycin 500 mg BID for 10 days
- Zollinger-Ellison Syndrome: 20–80 mg daily, adjusted individually
- Acid Dyspepsia: 20–40 mg daily for 2–4 weeks
- Duodenal Ulcer: 20 mg daily for 2–4 weeks
- Gastric Ulcer: 20–40 mg daily for 4–8 weeks
- Children: Not established.
- Elderly: No major differences observed, but individual sensitivity may vary.
- Liver Impairment: In severe hepatic insufficiency, limit dose to 20 mg/day.
- Kidney Impairment: No dose adjustment needed as <1% is excreted unchanged.
Capsules/Tablets: Swallow whole, 1 hour before meals.
✔️ Drug Interactions
- iMAX is metabolized mainly via CYP2C19 and CYP3A4.
- Minimal interaction with drugs metabolized by other CYP enzymes.
- Co-admin with diazepam may increase diazepam levels.
- Reduced absorption of drugs dependent on acidic pH (e.g., ketoconazole, iron salts, digoxin).
- Safe to use with oral contraceptives, phenytoin, quinidine, and antibiotics like amoxicillin and clarithromycin.
✔️ Contraindications
- Known hypersensitivity to esomeprazole or any capsule component.
- No difference in side effects seen between short-term and long-term use (up to 12 months).
✔️ Use During Pregnancy & Lactation
- Limited human data; animal studies show no teratogenic effects.
- Unknown if excreted in breast milk—discontinue breastfeeding if necessary.
✔️ Precautions
- Rule out gastric malignancy before starting iMAX.
- Can be taken with antacids.
- For patients unable to swallow capsules: contents can be sprinkled on soft applesauce and swallowed immediately (no chewing or storage).
✔️ Storage
- Store in a cool, dry place below 30°C.
- Protect from light and moisture.
- Keep out of children's reach.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
