Inpro (Omeprazole) is a proton pump inhibitor (PPI) that blocks the final step of gastric acid secretion. It inhibits the H⁺/K⁺-ATPase enzyme system in the stomach’s parietal cells, leading to potent and long-lasting acid suppression.
Onset: Within 1 hour of oral administration
Peak effect: Around 2 hours
Duration: Acid suppression lasts up to 72 hours
After stopping therapy, gastric acid secretion gradually returns to normal within 3–5 days.
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Proper Packaging
Inpro is indicated for the treatment and prevention of:
Omeprazole
Oral:
Gastric/Duodenal Ulcer: 20 mg once daily for 4–8 weeks (increase to 40 mg if necessary).
NSAID-Associated Ulcer: 20 mg once daily for 4–8 weeks; same dose for prevention.
GERD/Reflux Esophagitis: 20 mg once daily for 4–8 weeks; refractory cases may need 40 mg daily.
Long-Term Acid Reflux Management: 10–20 mg daily.
Acid Dyspepsia: 10–20 mg daily for 2–4 weeks.
Acid Aspiration Prophylaxis: 40 mg the evening before, then 40 mg 2–6 hours before surgery.
Zollinger–Ellison Syndrome: Start at 60 mg daily (may increase up to 120 mg in divided doses).
H. pylori Eradication: 20 mg twice daily with antibiotics for 7 days (Amoxicillin/Metronidazole or Clarithromycin combinations).
Pediatric (≥1 year):
10–20 kg: 10–20 mg daily for 4–12 weeks
20 kg: 20–40 mg daily for 4–12 weeks
Generally well tolerated.
Common: Headache, diarrhea, nausea, flatulence, constipation, abdominal discomfort.
Occasional: Rash, urticaria, dizziness, insomnia, or mild edema.
Rare: Hepatitis, pancreatitis, alopecia, photosensitivity, interstitial nephritis, or hematologic abnormalities.
Most adverse effects are mild and reversible upon discontinuation.
May reduce absorption of ketoconazole and similar drugs.
Can delay metabolism of diazepam, phenytoin, and warfarin—monitor closely.
Clarithromycin increases Omeprazole plasma levels (beneficial in H. pylori therapy).
Avoid combining with clopidogrel due to reduced antiplatelet effect.
May slightly increase digoxin bioavailability (≈10%).
No significant interaction with amoxicillin, caffeine, or NSAIDs.
Hypersensitivity to Omeprazole or any component.
Exclude malignancy before starting treatment for gastric ulcers, as Omeprazole may mask symptoms.
Studies show no harmful effects during pregnancy.
Safety during breastfeeding is not established — use only if necessary
Store in a cool, dry place, protected from light and heat.
Keep out of the reach of children.
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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.