Opton 20mg Tablet | Esomeprazole | ePharma
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Opton 20mg Tablet

Generic: Esomeprazole

Type: Tablet

Pack Size: 10 Pcs

Esomeprazole is used to treat:

  • Gastroesophageal reflux disease (GERD)
  • Stomach ulcers and intestinal ulcers caused by Helicobacter pylori infection and NSAIDs (Non-Steroidal Anti-Inflammatory Drugs)
  • Zollinger-Ellison syndrome

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Discount Price: ৳ 56.4
MRP: ৳ 60 6% Off

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✅ Description:

Opton 20mg Tablet, containing Esomeprazole, is a medication classified as a proton pump inhibitor (PPI). Opton 20mg Tablet is used for the treatment of conditions such as gastroesophageal reflux disease (GERD), heartburn, stomach ulcers or infections caused by Helicobacter pylori bacteria, and excessive stomach acid production associated with Zollinger-Ellison syndrome.

  • Opton 20mg Tablet helps reduce the production of stomach acid, providing relief from the symptoms of GERD. GERD occurs when acid from the stomach flows back into the esophagus, causing irritation and inflammation.
  • Opton 20mg Tablet is not recommended for children and adolescents under 12 years of age. Consult your doctor for advice before giving this medication to younger individuals.

Safety Advices


Alcohol
UNSAFE

Avoid or limit the consumption of alcohol while taking Opton 20mg Tablet because it might increase the amount of acid in your stomach than normal which can irritate your stomach lining and worsen your symptoms.


Pregnancy
CONSULT YOUR DOCTOR

Opton 20mg Tablet should be used during pregnancy only if considered clearly necessary. Consult your doctor before taking Opton 20mg Tablet.


Breastfeeding
CONSULT YOUR DOCTOR

Opton 20mg Tablet is not recommended for use in breastfeeding women as it is unclear whether it passes through the breast milk. Consult your doctor before taking Opton 20mg Tablet.


Driving
CAUTION

Do not drive or operate any heavy tools or machines if you experience dizziness and blurred vision after taking Opton 20mg Tablet. Consult your doctor before taking Opton 20mg Tablet


Kidney
SAFE IF PRESCRIBED

Opton 20mg Tablet should be used with caution in patients with severe kidney problems. Consult your doctor before taking Opton 20mg Tablet.


Liver
CAUTION

Opton 20mg Tablet should be used with caution in patients with severe liver problems. Consult your doctor before taking Opton 20mg Tablet.

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✔️ Uses of Opton 20mg Tablet
  • Treatment of Gastroesophageal reflux disease (Acid reflux)
  • Treatment of Peptic ulcer disease
✔️ How does Opton 20mg Tablet work?

Opton 20mg Tablet works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.

✔️ Side Effects of Opton 20mg Tablet
  • Headache
  • Diarrhea
  • Sleepiness
  • Dry mouth
  • Stomach pain
  • Constipation
  • Flatulence
  • Nausea
  • Vomiting
  • Swelling of the feet and ankles
  • Troubled sleep
  • Dizziness
  • Tingling sensations
  • Skin rash, bumpy rash (hives), and itchy skin
  • Fractures of joints such as the hip, wrist, or spine
  • Benign polyps in the stomach (masses of cells that form on the lining inside your stomach)
✔️ Quick Suggestions:
  • It is recommended to use this medicine in the prescribed manner. However, anti-reflux medicines should preferably be taken in the morning on an empty stomach or with food for optimum effectiveness.
  • You can make certain lifestyle modifications like preventing excess intake of foods that cause acidity, like carbonated drinks and oily/fried food, regular exercise, and maintaining a healthy weight.
  • It is also advised to limit alcohol intake and quit smoking for better treatment of your acidity.
  • It is advised to reduce stress and get good sleep each night.
  • Inform your doctor if you are using this medicine as a continuous treatment of acidity for more than 4 weeks or if the symptoms are persistent even after taking the medicine.
  • Opton 20mg Tablet can hamper the actions of other medicines taken simultaneously. Inform your doctor if you are using any other medicines.
✔️ Indication

Opton 20mg Tablet is an anti-ulcer medicine. It is used to treat stomach and intestinal conditions like peptic ulcers (sores in the lining of your stomach and intestine), esophagitis (swelling of your food pipe), and gastroesophageal reflux disease (a condition in which the stomach acid flows back into your food pipe), etc. It also relieves stress ulcers (sores in the stomach and intestine that may occur due to illness, infections, etc.) and acidity caused due to the intake of painkillers. It works by stopping the excess production of acid in your stomach.

✔️ Pharmacology

Esomeprazole, the active ingredient in Opton 20mg Capsule, works by preventing the final step of gastric acid production. It achieves this by binding covalently to the cysteine sulfhydryl group in the H+/K+ ATPase enzyme on the secretory surface of gastric parietal cells. This binding inhibits the production of gastric acid.

The inhibitory effect of esomeprazole on gastric acid secretion is not dependent on the specific stimulus. It effectively reduces both basal and stimulated acid secretion. Since the binding of esomeprazole to the H+/K+ ATPase enzyme is irreversible, new enzymes need to be synthesized to restore acid secretion. This means that the antisecretory effect of esomeprazole lasts for more than 24 hours.

In summary, esomeprazole acts by irreversibly binding to the H+/K+ ATPase enzyme, resulting in a long-lasting inhibition of gastric acid secretion.

✔️ Dosage & Administration of Opton 20mg Tablet

The adult and child doses for Opton 20mg Tablet, based on different indications, are as follows:

Adult Dose:

  • GERD Without Erosive Esophagitis: 20 mg orally once daily for 4 weeks. Consider an additional 4 weeks of treatment if symptoms do not completely resolve in the first 4 weeks.
  • GERD With Erosive Esophagitis: 20-40 mg orally once daily for 4-8 weeks. If oral therapy is not possible, intravenous administration of 20-40 mg once daily for up to 10 days can be considered. Switch to oral therapy once the patient is able to swallow.
  • Maintenance Therapy: 20 mg orally once daily for up to 6 months.
  • Risk Reduction of NSAID-Associated Gastric Ulcer: 20-40 mg orally once daily for up to 6 months.
  • NSAID-Induced Gastric Ulcer: 20 mg orally once daily for 4-8 weeks.
  • Zollinger-Ellison Syndrome: The initial dose is 80 mg orally divided every 12 hours. Adjust the regimen based on efficacy, up to a maximum of 240 mg orally once daily or 120 mg orally every 12 hours.

Child Dose:

GERD Without Erosive Esophagitis: Safety and efficacy not established for children below 1 year. For children 1-12 years old, the dose is 10-20 mg orally once daily for up to 8 weeks. For children above 12 years, the dose is 20-40 mg orally once daily for up to 8 weeks.

GERD With Erosive Esophagitis (Healing): Safety and efficacy not established for infants below 1 month. For infants 1 month to 1 year (weight-based dosing):

  • <3.5 kg: 2.5 mg orally once daily for up to 6 weeks.

3.5-7.5 kg: 5 mg orally once daily for up to 6 weeks.

7.5 kg: 10 mg orally once daily for up to 6 weeks. For children 1-12 years old, the dose is 10 mg orally once daily for 8 weeks if weight is <20 kg, and 10-20 mg orally once daily for 8 weeks if weight is >20 kg. For children above 12 years, the dose is 20-40 mg orally once daily for 4-8 weeks.

Maintenance Therapy: 20 mg orally once daily for up to 6 months.

Renal Dose: No dosage adjustment is needed for renal impairment.

It is important to follow the dosage instructions provided by your doctor. If you have any concerns or questions about the dosage or administration of Opton 20mg Tablet, consult your healthcare provider for further guidance.

Esomeprazole Tablet should be swallowed whole and taken one hour before a meal.

✔️ Interaction
  • Antibiotics used to treat ulcers caused by Helicobacter pylori infection (e.g., amoxicillin, clarithromycin).
  • Medicines used to treat HIV infection (e.g., nelfinavir, atazanavir).
  • Medicines used to prevent blood clots (clopidogrel, warfarin).
  • Anti-fungal medicines (e.g., ketoconazole, itraconazole, or voriconazole).
  • Medicine used to treat cancer (e.g., erlotinib).
  • Anti-depressants used to treat depression (e.g., citalopram, imipramine, clomipramine) or St. John's wort (Hypericum perforatum), which is an herbal supplement.
  • Medicines used to treat anxiety, relax muscles, or epilepsy (e.g., diazepam).
  • Medicine used in epilepsy (e.g., phenytoin).
  • Medicines used to treat intermittent pain in your legs caused by insufficient blood supply (e.g., cilostazol).
  • Medicines used for indigestion and heartburn (e.g., cisapride).
  • Digoxin (a medicine used for heart problems).
  • Methotrexate (a medicine used in high doses to treat cancer).
  • Immunosuppressants for organ transplantation (e.g., tacrolimus).
  • Medicines used for the treatment of tuberculosis (e.g., rifampicin).
  • Medicines that increase magnesium levels, such as diuretics (e.g., hydrochlorothiazide, chlorthalidone).
✔️ Contraindications

Esomeprazole is contraindicated in patients-

  • Have or ever had a skin reaction after taking medicine to treat acidity
  • Are going to have a specific blood test (Chromogranin A)
  • Are losing a lot of weight without reason
  • Have problems swallowing, stomach pain, or indigestion
  • Pass black stools (blood-stained feces)
  • Have skin rashes especially after getting exposed to sun
  • Have joint pain
✔️ Pregnancy & Lactation

During pregnancy, there is limited information available regarding the safety of esomeprazole (the active ingredient in Opton 20mg Tablet). Here is some information based on available data:

Pregnancy: There are no adequate and well-controlled studies in pregnant women specifically for esomeprazole. However, esomeprazole is the S-isomer of omeprazole, and epidemiologic data on omeprazole use during the first trimester of pregnancy have not shown an increased risk of major congenital malformations or other adverse pregnancy outcomes. Animal studies with omeprazole have shown dose-dependent embryo-lethality at doses approximately 3.4 to 34 times higher than the oral human dose of 40 mg (based on body surface area for a 60 kg person). It is important to discuss the risks and benefits with your doctor before using Opton 20mg Tablet during pregnancy.

Lactation: Esomeprazole is the S-isomer of omeprazole, and limited data suggest that omeprazole may be present in human milk. There are no clinical data available on the effects of esomeprazole on breastfed infants or on milk production. It is recommended to consider the developmental and health benefits of breastfeeding along with the mother's clinical need for therapy and any potential adverse effects on the breastfed infant from treatment or from the underlying maternal condition. It is advisable to consult your doctor for personalized advice regarding the use of Opton 20mg Tablet while breastfeeding.

In any case, it is essential to have a discussion with your doctor regarding the potential risks and benefits of using Opton 20mg Tablet during pregnancy or while breastfeeding. Your doctor can provide you with the most appropriate guidance based on your specific situation and medical history.

✔️ Precautions & Warnings
  • For pediatric use, the specific dosing and safety of Opton 20mg Tablet may vary depending on the age and condition of the child. It is important to consult with a pediatrician for appropriate dosing and guidance.
  • Regarding pregnancy and lactation, as mentioned earlier, limited data suggest that omeprazole (of which esomeprazole is the S-isomer) may be present in human milk. There are no clinical data available on the effects of esomeprazole on breastfed infants or on milk production. The decision to use Opton 20mg Tablet during breastfeeding should be made by considering the developmental and health benefits of breastfeeding alongside the mother's clinical need for the medication and any potential risks to the breastfed infant from the medication or the underlying maternal condition. It is advisable to consult a healthcare professional for personalized advice in such cases.
  • Regarding malignancy (cancer) and hepatic impairment (liver impairment), it is important to follow the guidelines and precautions provided by your doctor. Patients with severe liver impairment should not exceed a dose of 20 mg of esomeprazole.
  • Lastly, the use of proton pump inhibitors, including esomeprazole, has been associated with an increased risk of developing certain infections such as community-acquired pneumonia. It is important to be aware of this risk and discuss it with your doctor, especially if you have a history of recurrent infections or other risk factors.

It is crucial to consult with a healthcare professional for comprehensive and personalized information regarding the use of Opton 20mg Tablet in specific medical conditions, including pediatric use, pregnancy, lactation, malignancy, and hepatic impairment.

✔️ Storage Conditions

Store in a dry area at a temperature of not more than 30°C. Light and dampness should be avoided. Keep out of children's reach.

Frequently Asked Questions (FAQ)

Opton 20mg Tablet is often only recommended for brief periods of time. But Opton 20mg Tablet can also be recommended for a long time if necessary, for example to treat Zollinger Ellison syndrome (ZES) and peptic ulcer disease. The risks of adverse effects may rise with long-term usage; this must be discussed with the doctor. Please follow your doctor's instructions and take Opton 20mg Tablet just as directed by them.

Yes, you can take antacids along with Opton 20mg Tablet. Take it 2 hours before or after you take Opton 20mg Tablet.

Opton 20mg Tablet is typically used once daily in the morning. Take 1 dosage of Opton 20mg Tablet in the morning and 1 tablet in the evening if you take it twice a day. The pills should be taken whole, with some water, at least one hour before a meal (remember, do not chew or crush them).

No

The proton pump inhibitor family of drugs, which includes the structurally distinct molecules esomeprazole and pantoprazole, helps to reduce heartburn and chest discomfort by reducing the production of stomach acid. Both molecules may work slightly differently from one another, and they may also have distinct adverse effects and interactions with other medications. It is advised that you follow your doctor's prescription for medicines and refrain from self-medicating.The proton pump inhibitor family of drugs, which includes the structurally distinct molecules esomeprazole and pantoprazole, helps to reduce heartburn and chest discomfort by reducing the production of stomach acid. Both molecules may work slightly differently from one another, and they may also have distinct adverse effects and interactions with other medications. It is advised that you follow your doctor's prescription for medicines and refrain from self-medicating.

No, this medicine is not recommended for use by children as there is limited safety-related data for use in children under 12 years of age.

The majority of the time, this drug takes 1 to 3 days on average to attain its greatest impact. It is not a conventional amount of time for this medication's effect because the same timeframe is not required for everyone. For the duration that you must use this drug, please visit your doctor.

Opton 20mg Tablet may remains in your body for an average duration of 9 hours.

No, this medicine does not reduce gas. However, it helps to relieve heartburn and pain due to increased acidity.

Yes, studies have suggested that prolonged use of Opton 20mg Tablet for 3 months may lead to low magnesium levels that may cause side effects like tiredness, confusion, dizziness and irregular heartbeats. Long term use for more than a year may lead to making your bone weak with increased risk of fractures, Vitamin B12 deficiency, increased risk of stomach infections along with irregular heartbeats, indigestion and gases.
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Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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