Seclo 20mg Capsule

✔️ Uses of Seclo 20

• Gastroesophageal reflux disease (Acid reflux)
• Treatment of Peptic ulcer disease
• Treatment of Stomach Ulcer
• Hyperacidity

✔️ How to use Seclo 20

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Seclo 20 is to be taken empty stomach.

✔️ How Seclo 20 works

Seclo 20 is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.

✔️ What if you forget to take Seclo 20?

If you miss a dose of Seclo 20, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

✔️ Side effects of Seclo 20

• Diarrhea
• Flatulence
• Headache
• Nausea
• Stomach pain
• Vomiting

✔️

• Seclo 20 is a well-tolerated medicine and provides relief for a long time.
• Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
• Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
• Long-term use of Seclo 20 Capsule can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or supplements as prescribed by your doctor.

Do not stop taking Seclo 20 without talking to your doctor. 

• Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.

Some healthy tips to prevent acidity from happening:

• Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, and caffeinated beverages like tea and coffee.
• Avoid alcohol and smoking.
• Avoid eating late at night or before bedtime

✔️ Indications of Seclo 20

Omeprazole is used to treat the following conditions:

• Duodenal and gastric ulcers
• Long-term acid reflux disease management
• Dyspepsia caused by acid
• Esophagitis with severe ulcerating reflux
• Acid aspiration prevention during general anesthesiaDuodenal and stomach ulcers caused by NSAIDs
• As a preventative measure in individuals with a history of NSAID-related duodenal and stomach ulcers.
• GERD is an abbreviation for gastroesophageal reflux disease.
• Zollinger-Ellison syndrome is a condition in which there is a buildup of toxins in
• A peptic ulcer caused by Helicobacter pylori.

✔️ Pharmacology

Omeprazole, a substituted benzimidazole, is a stomach acid secretion inhibitor. It reduces stomach acid secretion by inhibiting the enzyme system of hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) in the gastric parietal cell. The antisecretory action begins within one hour of oral administration, with the greatest impact happening within two hours and secretion suppression lasting up to 72 hours. When the medication is stopped, secretory activity gradually recovers over 3 to 5 days.

✔️ Dosage & Administration of Seclo 20

Oral-

Gastro-Esophageal Reflux Disease: 

• 20 mg once daily for 4 weeks, continued for further 4-8 weeks if not fully healed; 40 mg once daily has been given for 8 weeks in gastro-esophageal reflux disease, refractory to other treatment; maintenance dose is 20 mg once daily.

Benign Gastric and Duodenal Ulcer: 

• 20 mg once daily for 4 weeks in Duodenal Ulceration, 8 weeks in gastric ulceration; in severe or recurrent cases, the dose is to be increased to 40 mg daily; maintenance dose for recurrent duodenal ulcer, 20 mg once daily; in the prevention of relapse in duodenal ulcer, 10-20 mg daily.

NSAID-associated Duodenal or Gastric Ulcer: 

• 20 mg once daily for 4 weeks, continued for further 4 weeks if not fully healed. 20 mg once daily is used as prophylaxis in patients with a history of NSAID-associated duodenal or gastric ulcers.

Long-term management of Acid Reflux Disease: 

• 10-20 mg daily.

Acid-related Dyspepsia: 

• 10-20 mg once daily for 2-4 weeks.

Prophylaxis of Acid Aspiration: 

• 40 mg on the preceding evening, then 40 mg 2-6 hours before surgery.

Zollinger-Ellison Syndrome: 

• Initially 60 mg once daily; the usual range is 20-120 mg daily (If the daily dose is more than 80 mg, 2 divided doses should be used).

Helicobacter Pylori Eradication Regimen in Peptic Ulcer Disease: 

• Omeprazole is recommended at a dose of 20 mg twice daily in association with antimicrobial agents as detailed below: Amoxicillin 500 mg and Metronidazole 400 mg both three times a day for one week, or Clarithromycin 250 mg and Metronidazole 400 mg both twice a day for one week, or Amoxicillin 1 g and Clarithromycin 500 mg both twice a day for one week.

Pediatric use in severe ulcerating reflux esophagitis (Child>1 year): 

• If body-weight 10-20 kg, 10-20 -mg once daily for 4-12 weeks;
• if body weight is over 20 kg, 20-40 mg once daily for 4-12 weeks.

✔️ Interaction of Seclo 20

Omeprazole can cause diazepam, warfarin, and phenytoin to be eliminated more slowly. When Omeprazole is added to the therapy, the amount of warfarin or phenytoin may need to be reduced. Omeprazole does not appear to interact with theophylline, propranolol, or antacids.

✔️ Contraindications

Omeprazole is not recommended for people who have a history of hypersensitivity to any of the formulation's components.

✔️ Pregnancy & Lactation

• Omeprazole is classified as pregnancy category C by the US Food and Drug Administration. However, the findings of three prospective epidemiological studies show that Omeprazole has no negative effects on pregnancy or the health of the fetus/newborn child.
• There is no information on Omeprazole's entry into breast milk or its effects on the newborn. If the usage of Omeprazole is deemed necessary, breastfeeding should be terminated.

✔️ Precautions & Warnings

• When a stomach ulcer is suspected, the potential of gastric cancer should be ruled out before starting Omeprazole treatment, as the medication may relieve symptoms while delaying detection
• The risk of adverse effects may rise with continued use of this medication. For instance, using this medication for a longer period of time, especially at larger doses, may raise your risk for bone fractures. Consult your physician about measures to stop bone loss.
• Inform your physician before using Seclo 20 if you have or have previously had serious liver issues, an allergy to comparable medications, or bone loss.
• Seclo 20 may have an impact on or interact with several other medications. To ensure it is safe, let your doctor know about all other medications you are taking. If you take medications for HIV, fungus infections, TB, epilepsy (fits), or certain blood thinners, this is very crucial.

✔️ Storage Conditions

Keep away from light and heat in a dry area. Keep out of children's reach.