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Indications
Rheumatoid arthritis can range from mild to severe; tocit XR is used to treat it. Lowering inflammation, it aids in reducing joint discomfort, soreness, and swelling. Additionally, it aids in delaying the deterioration of bones and joints. It is possible to prescribe Tocit XR alone or in conjunction with another drug.
Dosage and Administration
The recommended dose is 11 mg once daily.Or, as directed by the registered physician.
Interaction
Tofacitinib exposure is increased when Tofacitinib is co-administered with potent inhibitors of cytochrome P450 (CYP) 3A4 (e.g., ketoconazole) and CYP2C19 (e.g., fluconazole). Use of tofacitinib in combination with biologic DMARDs or potent immune suppressants such as azathioprine and cyclosporine is not recommended.
Contraindications
It is contraindicated in patients with hypersensitivity to Tofacitinib or any other components of this product.
Side Effects
The most common side effects arediarrhoea, nasopharyngitis, upper respiratory tract infection, headache and hypertension.
Pregnancy and lactation
Pregnancy Category C. There are no adequate and well-controlled studies in pregnant women. Tofacitinib should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether this medicine is excreted in human milk. Caution should be exercised when this product is administered to a nursing woman.
Precautions & Warnings
Use of Tofacitinib should be avoided in patients with an active infection, including localized infections. Patients with latent tuberculosis should be treated with standard antimycobacterial therapy before administering Tofacitinib.
Storage Conditions
Store below 25o C in a dry place.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.