Utal 5mg Tablet | Gynecologic Medicine | Uses | Interaction | ePharma
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Utal 5mg Tablet

Generic: Ulipristal Acetate

Type: Tablet

Pack Size: 10 Pcs

Ulipristal Acetate is employed before surgery to address moderate to severe symptoms of uterine fibroids, which are benign growths within the uterus. This treatment is intended for adult women who have not yet undergone menopause.


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Discount Price: ৳ 517.75
MRP: ৳ 545 5% Off

⪼ Save  ৳: 27.25  in this Product


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✅ Description:

Utal 5mg Tablet contains ulipristal acetate, which is utilized to address moderate to severe symptoms of non-cancerous uterine fibroids in adult women before menopause. These fibroids can lead to heavy menstrual bleeding, pelvic pain, and pressure on adjacent organs. The medication functions by altering the effects of progesterone, a naturally occurring hormone in the body.

It is crucial to note that Utal 5mg Tablet is not suitable for individuals under 18 years of age due to the lack of established safety and efficacy data for ulipristal acetate in this age group. For pregnant or breastfeeding individuals, consulting a doctor before using this medication is advisable. While taking this medicine, consumption of grapefruit juice should be avoided. The recommended dosage entails one 5 mg tablet per day, adhering to treatment courses lasting up to 3 months each, or as directed by a physician. Commencing the medication within the first week of the menstrual period is essential. The tablet should be swallowed with water and can be taken with or without food.

Safety Advices


Alcohol
UNSAFE

Avoid consumption of alcohol while taking this medicine.


Pregnancy
CONSULT YOUR DOCTOR

Utal 5mg Tablet is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.


Breastfeeding
CONSULT YOUR DOCTOR

Utal 5mg Tablet is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.


Driving
CAUTION

Do not drive or operate any machinery while taking this medicine, it may be affected by dizziness.


Kidney
CONSULT YOUR DOCTOR

Utal 5mg Tablet should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.


Liver
CONSULT YOUR DOCTOR

Utal 5mg Tablet should be taken with caution in patients with severe liver disease. Consult your doctor for advice.

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✔️ Uses of Utal 5mg Tablet
  • Treat moderate to severe symptoms of the uterine fibroids
✔️ How does Utal 5mg Tablet work?

Utal 5mg Tablet works by blocking the effects of progesterone which play a role in the development of fibroids This stops the fibroids from growing and shrinking in size.

✔️ Side Effects of Utal 5mg Tablet
  • Fatigue
  • Headache
  • Dizziness
  • Breast Tenderness
  • Back Pain
  • Mood Changes
  • Pelvic Pain
  • Painful Menstruation
  • Muscle Pain
  • Abdominal Pain
  • Myalgia
  • Acne
  • Pruritus
  • Dry Mouth
  • Flatulence
  • Chills
✔️ Quick Suggestions:
  • Utal is prescribed to address uterine fibroids and the symptoms they cause, including painful menstrual periods, excessive bleeding, and pelvic discomfort.
  • It is notably effective in significantly reducing or halting menstrual bleeding within the initial 10 days of treatment. If despite using Utal you continue to experience heavy bleeding, it's essential to inform your doctor.
  • Following the cessation of Utal usage, your menstrual periods typically resume within approximately four weeks.
  • During the time you are taking Utal, it's advisable to utilize a reliable barrier contraceptive method such as condoms or a diaphragm, as the medication might diminish the effectiveness of hormonal contraceptives like pills.
  • Your healthcare provider might recommend routine liver function tests to assess the health of your liver.
  • If you notice symptoms like yellowing of the skin or eyes (jaundice), dark-colored urine, or abdominal pain, it's important to notify your doctor promptly.
✔️ Indication of Utal 5mg Tablet

Utal 5mg Tablet is a versatile medication employed for two primary purposes. Firstly, it is utilized intermittently to address the moderate to severe symptoms of uterine fibroids, which are abnormal growths within the uterus. Additionally, it serves as an emergency contraceptive.

In the context of treating uterine fibroids, adult women who have not yet reached menopause (the cessation of menstruation) are typically administered lower doses of Utal 5mg Tablet, with options ranging from 5mg to 15mg. This helps manage the symptoms associated with fibroids effectively.

Alternatively, when utilized as an emergency contraceptive, Utal 5mg Tablet is administered in higher doses, generally at 30mg. This dosage aids in preventing unintended pregnancy when taken within a certain timeframe after unprotected intercourse.

✔️ Pharmacology

Ulipristal acetate is a selective progesterone receptor modulator. Its mechanism of action involves inhibiting the receptor for a hormone called progesterone in the body. Progesterone plays a role in regulating the growth of the uterine lining. In certain cases, progesterone can promote the growth of fibroids, leading to symptoms like heavy uterine bleeding, fatigue, and abdominal discomfort.

By blocking progesterone activity, ulipristal acetate effectively stops fibroid cells from proliferating and eventually causes their regression. This reduction in fibroid size leads to a decrease in the associated symptoms.

✔️ Dosage & Administration of Utal 5mg Tablet

For adults, the dosing guidelines for Ulipristal Acetate are as follows:

Oral Emergency Contraception: Take one tablet orally as soon as possible within 120 hours (5 days) after unprotected intercourse or when there's a known or suspected contraceptive failure. If vomiting occurs within 3 hours of taking Ulipristal Acetate, consider taking another dose.

Uterine Fibroids: For treating uterine fibroids, the recommended dose is 1 tablet of 5 mg taken orally once daily. This treatment should continue for up to 3 months. The 3-month treatment course can be repeated once. The re-treatment should ideally begin during the second menstruation following the completion of the first treatment course. It's important to initiate treatment during the first week of menstruation. If a dose is missed, the patient should take Ulipristal Acetate as soon as possible. If more than 12 hours have passed since the missed dose, the patient should not take the missed dose and should resume the usual dosing schedule.

The tablet should be swallowed with water and can be taken with or without food. It's recommended to follow these dosing instructions as provided or as directed by your doctor.

✔️ Interaction

Indeed, it is not recommended to concurrently use medicinal products that contain progestagens along with ulipristal acetate. Additionally, the simultaneous use of ulipristal acetate and potent CYP3A4 inducers such as rifampicin, rifabutin, carbamazepine, oxcarbazepine, phenytoin, fosphenytoin, phenobarbital, primidone, St. John's wort, efavirenz, nevirapine, and long-term use of ritonavir is not recommended.

CYP3A4 inducers can influence the metabolism of ulipristal acetate, potentially impacting its effectiveness. It's important to follow medical advice and guidance when taking these medications in combination to ensure their safe and effective use.

✔️ Contraindications

Ulipristal Acetate should not be used in the following situations:

  • Known or Suspected Pregnancy: It is contraindicated if pregnancy is known or suspected.
  • Hypersensitivity: If there is a known hypersensitivity or allergic reaction to ulipristal acetate or any of its components, the use of the medication is not recommended.
  • Genital Bleeding: It should not be used in cases of genital bleeding of unknown cause or for reasons other than treating uterine fibroids.
  • Cancer: Contraindicated in cases of uterine, cervical, ovarian, or breast cancer.
  • Breastfeeding: Ulipristal Acetate is not recommended for use during breastfeeding.

In all these situations, it is important to avoid using Ulipristal Acetate, and individuals should consult their healthcare provider for appropriate alternatives and guidance.

✔️ Pregnancy & Lactation

The pregnancy category for ulipristal acetate is Category X, which indicates that it is not recommended for use during pregnancy due to the potential risks to the developing fetus.

Additionally, it's important to note that ulipristal acetate can be excreted into human milk. Therefore, it is not advisable to use this medication while breastfeeding, as it may affect the infant through breast milk. It's always best to consult with a healthcare professional before using any medication, especially during pregnancy and while breastfeeding.

✔️ Precautions & Warnings
  • Existing Pregnancy: Ulipristal Acetate is not meant for terminating an existing pregnancy. It's crucial to ensure that pregnancy is excluded before prescribing this medication.
  • Ectopic Pregnancy: A history of ectopic pregnancy doesn't preclude the use of this emergency contraceptive method.
  • Repeated Use: Ulipristal Acetate is intended for occasional use as an emergency contraceptive. It should not replace regular contraception. Repeated use within the same menstrual cycle is discouraged due to a lack of evaluated safety and efficacy.
  • Fertility After Use: Fertility can return quickly after using Ulipristal Acetate for emergency contraception. It's important to resume or initiate routine contraception promptly after use to continue preventing pregnancy.
  • Effect on Menstrual Cycle: Ulipristal Acetate might cause menstrual periods to occur a few days earlier or later than expected.
  • Contraception: Concomitant use with progestagen-only pills, a progestagen-releasing intrauterine device, or combined oral contraceptive pills is not recommended. While most women using ulipristal acetate experience anovulation (lack of ovulation), a non-hormonal contraceptive method is still recommended during treatment.
  • Sexually Transmitted Infections/HIV: Ulipristal Acetate does not protect against HIV or other sexually transmitted infections.
  • Endometrial Changes: The use of ulipristal acetate may lead to reversible changes in the histology of the endometrium (uterine lining). These changes should not be confused with endometrial hyperplasia (abnormal increase in the thickness of the uterine lining).
✔️ Storage Conditions

Protect from light and moisture by storing in a cool, dry place below 30°C. Keep out of children's reach.

Frequently Asked Questions (FAQ)

Utal 5mg Tablet takes 1-2 hours to show its effect.

Utal 5mg Tablet's effectiveness lasts for approximately 9-10 days for fibroid treatment and up to 8 days when used as an emergency contraceptive (30mg).

Ulipristal acetate should be taken orally as soon as possible after unprotected sex or contraceptive failure and not later than 120 hours (5 days). It can be taken at anytime of the day and before, during or after food. It can be taken at anytime during your menstrual cycle.

If vomiting occurs immediately after or within 3 hours of taking Ulipristal acetate, take another tablet. Vomiting beyond 3 hours does not require an additional tablet.

Ulipristal acetate may make your birth control pills less effective and therefore in addition to birth control pills you should continue using condoms till your next period (menses).

Taking a single tablet of Ulipristal acetate doesn't halt periods; however, it might either delay or shift the timing of your periods. Occasionally, there might be bleeding between periods. Should this occur, it's advisable to consult your doctor.

Ulipristal acetate works by obstructing progesterone receptors, which subsequently reduces progesterone levels. This mechanism aids in diminishing the size of fibroids, which are benign growths near the uterus. Administered at the prescribed dose, Ulipristal acetate prevents ovulation, leading to the cessation of menstrual periods. This effect can be particularly beneficial for women experiencing heavy bleeding caused by fibroids.

This medication is a Selective Progesterone Receptor Modulator (SPRM) that is used as an emergency contraceptive and a medication for uterine fibroid. It is used for the prevention of pregnancy in case any regular method of birth control failed.
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Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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