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Adrinor 1mg/ml Inejction
Adrinor Injection (Adrenaline/Epinephrine) | Anaphylaxis management, Mydriatic and Cycloplegic agents, Adrenoceptor stimulants, Respiratory stimulants
Pregnancy Category C: Use only if benefits justify the potential risk.
Excreted in breast milk; not recommended during lactation due to possible effects on infants.
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ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
✅ Description:
Adrinor is a fast-acting sympathomimetic agent that acts directly on alpha and beta-adrenergic receptors. It is primarily used in cardiopulmonary resuscitation (CPR) and the emergency treatment of anaphylaxis, severe asthma, and cardiac arrest. It enhances cardiac output, increases blood pressure and heart rate, promotes bronchodilation, raises blood glucose levels, and reduces inflammatory responses caused by histamines.
Adrinor (epinephrine) stimulates both alpha- and beta-adrenergic receptors:
- Alpha-1 effects: Vasoconstriction leading to increased systolic blood pressure.
- Beta-1 effects: Enhanced heart rate and contractility.
- Beta-2 effects: Bronchodilation and metabolic effects (e.g., increased blood glucose).
Pharmacokinetics
- Onset: Rapid
- Half-life: 5–10 minutes
- Metabolism: Liver (MAO and COMT)
- Excretion: ~90% via urine as metabolites
- Protein Binding: ~50%
✔️ Side Effects
- Anxiety, restlessness, dizziness
- Headache, palpitations, tremors
- Rapid pulse, cold extremities
✔️ Uses
- Cardiac arrest (as adjunctive therapy)
- Anaphylactic reactions
- Severe bronchospasm or asthma unresponsive to nebulizers
- Prolonging local anesthesia (intraspinal use)
✔️ Dosage & Administration
Cardiac Arrest:
IV: 1 mg every 2–3 minutes as needed
Endotracheal: 2–3 mg via ETT, repeat as required
Intracardiac: 0.1–1 mg directly into the heart (atrium)
Intraspinal: 0.2–0.4 mg mixed with spinal anesthetic
Anaphylaxis/Asthma (Adults):
0.25–0.5 mg IM or SC; may repeat every 5 minutes until stable
Dilution (if needed): 1 mg diluted in 9 ml normal saline.
Pediatrics:
Initial dose: 10 mcg/kg (max 250 mcg), repeat every 3–5 min if needed
Maintenance: 100 mcg/kg for subsequent doses
🛑 Always use under the guidance of a registered physician.
✔️ Overdose Management
Symptoms: Severe hypertension, arrhythmias, pulmonary edema, cerebral hemorrhage
- Beta-blockers (for tachyarrhythmias)
- Phentolamine (to counter alpha effects)
- Vasodilators like nitrates or sodium nitroprusside
- Ensure immediate resuscitation support is available
✔️ Interaction
- Increased risk of arrhythmias with digitalis, mercurial diuretics
- Enhanced side effects with tricyclic antidepressants, certain antihistamines, and thyroid hormones
✔️ Contraindications:
- Uncontrolled hypertension
- Coronary artery disease
- Arteriosclerosis
- Hyperthyroidism
- Concurrent use with MAO inhibitors
✔️ Precautions
- Use cautiously in elderly patients or those with heart disease, diabetes, asthma, or psychiatric disorders.
- Do not use discolored or precipitated solutions.
- Avoid mixing with sodium bicarbonate or oxidizing agents.
✔️ Storage:
- Store below 25°C
- Protect from light
- Keep out of reach of children
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
