Acetor 25mg Tablet 10pcs

✔️ Uses of Acetor 25

• Hypertension
• Congestive heart failure
• Left ventricular dysfunction
• Diabetic nephropathy

✔️ Side Effects: Acetor 25

Potential side effects may include:

• Neutropenia, anemia, proteinuria
• Hypotension, tachycardia
• Rash (usually pruritic), gastric irritation, abdominal pain

✔️ How does Acetor 25 work?

Captopril is an angiotensin-converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessels so that blood flows more smoothly and the heart can pump blood more efficiently.

✔️ Quick Suggestions:

• Captopril can make you feel dizzy for the first few days, so rise slowly if you have been sitting or lying down. You can also prefer taking it at bedtime to avoid dizziness throughout the day.
• Let your doctor know about any cough, or throat irritation that does not go away.
• It may increase the level of potassium in the blood. Avoid taking potassium supplements and potassium-rich foods.
• Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

✔️ Acetor is indicated for:

• Mild-to-moderate hypertension: As an adjunct to thiazide therapy in patients who have not responded effectively to thiazide treatment alone.
• Severe hypertension: In cases where standard therapy has failed.
• Congestive heart failure: As part of a treatment regimen that includes diuretics and, where appropriate, digitalis.

Note: Always consult a registered healthcare professional before use.

✔️ Pharmacology

Captopril is a sulfhydryl-containing analog of proline with antihypertensive properties. It works by competitively inhibiting angiotensin-converting enzyme (ACE), leading to decreased levels of angiotensin II, increased plasma renin activity, and decreased aldosterone secretion. Approximately 60-75% of an oral dose of captopril is rapidly absorbed from the gastrointestinal tract in fasting healthy individuals or hypertensive patients. More than 95% of the dose is excreted renally, both as unchanged drug (45-50%) and as metabolites.

✔️ Dosage & Administration: Acetor 25

Adults:

Mild-to-moderate hypertension: Initial dose of 12.5 mg twice daily. The usual maintenance dose is 25 mg twice daily, which may be increased incrementally every two to four weeks until a satisfactory response is achieved, with a maximum of 50 mg twice daily.

Severe hypertension: The starting dose is 12.5 mg twice daily, which may be increased incrementally to a maximum of 50 mg three times daily.

Heart failure: A starting dose of 6.25 mg or 12.5 mg is recommended to minimize transient hypotensive effects. The usual maintenance dose is 25 mg three times daily, with a maximum daily dose of 150 mg.

Captopril should be taken 1 hour before meals to ensure maximum absorption.

• Use in Children: Safety and effectiveness in pediatric patients have not been established.

Note: Always follow the guidance of a registered healthcare professional regarding use.

✔️ Interaction

Do not coadminister aliskiren with Acetor in patients with diabetes. Renal function should be monitored periodically in such cases.

✔️ Contraindications

• History of hypersensitivity to captopril.
• Contraindicated in pregnancy and should not be used in women of childbearing potential unless protected by effective contraception.

✔️ Pregnancy & Lactation

There are no available data on pregnant women to inform the drug-associated risk. A decision should be made whether to discontinue nursing or to discontinue the drug due to potential serious adverse reactions.

✔️ Precautions & Warnings

• Evaluate renal function before initiating Acetor therapy and at appropriate intervals thereafter.
• Caution is advised in patients with renal impairment, and Acetor should not be used in patients with aortic stenosis or outflow tract obstruction.

✔️ Storage:

Keep below 30°C, away from light and moisture. Keep out of the reach of children.