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Ropitor 40 is a cholesterol-lowering statin that blocks the enzyme HMG-CoA reductase, which is essential for cholesterol production in the liver. It reduces LDL (bad cholesterol) and triglycerides while increasing HDL (good cholesterol).
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✅ Description:
Rosuvastatin
- High cholesterol (Hyperlipidemia)
- Mixed dyslipidemia
- Familial hypercholesterolemia (heterozygous and homozygous)
- Prevention of cardiovascular events (heart attack, stroke)
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Dosage & Administration
Adults:
- Initial dose: 5–10 mg once daily
- Maintenance: Up to 20 mg daily; Maximum: 40 mg/day
Administration: May be taken with or without food, preferably at the same time daily
Children (10+ years):
- Start with 5 mg once daily; may increase to max 20 mg/day
Renal Impairment:
- For CrCl <30 mL/min: Max 10 mg/day
- Not recommended in severe renal failure, not on dialysis
✔️ Drug Interactions
- May increase the effects of warfarin, oral contraceptives
- Interacts with itraconazole, HIV protease inhibitors, gemfibrozil, cyclosporin – increased risk of rhabdomyolysis
- Reduced effect with antacids, erythromycin
✔️ Side Effects
- Muscle pain (myalgia), fatigue, headache
- Abdominal pain, nausea, constipation
- Dizziness, increased liver enzymes
- Flu-like symptoms, pharyngitis
- Myopathy, rhabdomyolysis (potentially fatal)
- Jaundice, elevated creatine kinase
✔️ Contraindications
- Active liver disease
- Severe renal impairment
- Pregnancy or breastfeeding
- Unexplained persistent elevation of liver enzymes
- Hypersensitivity to rosuvastatin
✔️ Precautions & Monitoring
- Monitor liver function and creatine kinase (CK)
- Use cautiously in patients with renal impairment, hypothyroidism, alcoholism, or chronic liver disease
- Discontinue if signs of muscle toxicity or significant enzyme elevation occur
✔️ Pregnancy & Lactation
Contraindicated. Statins can harm fetal development and may pass into breast milk. Use effective contraception while on therapy.
✔️ Storage
Store in a cool, dry place, away from light and moisture. Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
