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Xerova EZ 10/10 Tablet 1 Strip
Atorvastatin
Atorvastatin lowers plasma cholesterol and lipoprotein levels by inhibiting HMG-CoA reductase, a key enzyme involved in hepatic cholesterol synthesis. It also increases hepatic LDL receptor expression, enhancing LDL uptake and clearance from the bloodstream while reducing LDL particle production.
Ezetimibe
Ezetimibe decreases serum cholesterol by selectively inhibiting intestinal cholesterol absorption. It targets the Niemann-Pick C1-Like 1 (NPC1L1) transporter in the small intestine, reducing the delivery of dietary and biliary cholesterol to the liver. This results in reduced hepatic cholesterol stores and increased clearance of circulating cholesterol.
This mechanism is complementary to statins and does not affect hepatic cholesterol synthesis, bile acid excretion, or fat-soluble vitamin levels.
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Price: ৳ 110
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Regular Delivery - 12-24 Hours, Dhaka City* Charge Tk.39-59- Regular Delivery - 24-48 Hours, Other Cities* Charge Tk.99-110
ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
- Cash on Delivery - All over Bangladesh
- Regular Delivery - 12-24 Hours, Dhaka City* Charge Tk.39-59
- Regular Delivery - 24-48 Hours, Other Cities* Charge Tk.99-110
- ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে
- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
✅ Description:
Lipid-modifying therapy should be considered as part of a comprehensive cardiovascular risk-reduction strategy in patients with a significantly increased risk of atherosclerotic vascular disease due to hypercholesterolemia. Pharmacological treatment is recommended as an adjunct to dietary modification and lifestyle interventions when non-drug measures alone fail to achieve adequate lipid control.
Primary Hyperlipidemia
Xerova EZ Tablet is indicated to reduce elevated levels of:
- Total cholesterol (Total-C)
- Low-density lipoprotein cholesterol (LDL-C)
- Apolipoprotein B (Apo-B)
- Triglycerides (TG)
Non-HDL cholesterol
It also helps increase high-density lipoprotein cholesterol (HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipidemia or mixed dyslipidemia.
Homozygous Familial Hypercholesterolemia (HoFH)
Xerova EZ Tablet is indicated to lower total cholesterol and LDL-C in patients with HoFH, either as an adjunct to other lipid-lowering therapies (such as LDL apheresis) or when such therapies are unavailable.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Side Effects of Xerova EZ 10
- Myalgia
- Myopathy
- Rhabdomyolysis
- Elevated liver enzymes
- Abdominal discomfort
✔️ Dosage & Administration | Xerova EZ 10
- Dose range: 10/10 mg to 80/20 mg once daily
- Recommended starting dose: 10/10 mg or 20/10 mg once daily
- For patients requiring >55% LDL-C reduction: 40/10 mg once daily
- Can be taken at any time of day, with or without food
- Lipid levels should be assessed at least 2 weeks after initiation or dose adjustment.
Pediatric Use: Safety and efficacy not established
Geriatric Use: No dosage adjustment required
Homozygous Familial Hypercholesterolemia
- Recommended dose: 40/10 mg or 80/10 mg once daily
- Use as adjunct therapy to LDL apheresis or when other options are unavailable
Hepatic Impairment
- Contraindicated in patients with active liver disease or persistent unexplained elevations in liver enzymes.
Renal Impairment
- No dose adjustment required; however, patients should be monitored closely for muscle-related adverse effects.
✔️ Pregnancy & Lactation
Pregnancy Category X
Contraindicated during pregnancy due to potential fetal harm
Lipid-lowering therapy provides no benefit during pregnancy
Breastfeeding is not recommended as statins may pass into breast milk
✔️ Contraindications
- Active liver disease
- Persistent unexplained elevations in hepatic transaminases
- Hypersensitivity to any component of the formulation
✔️ Drug Interactions
- Increased risk of myopathy with fibrates, high-dose niacin, cyclosporine, and strong CYP3A4 inhibitors
- Avoid co-administration with cyclosporine and gemfibrozil
- Use caution with niacin, colchicine, digoxin, warfarin, and oral contraceptives
- INR monitoring is recommended when used with warfarin
✔️ Precautions & Warnings
- Monitor for muscle symptoms and discontinue if myopathy or rhabdomyolysis is suspected
- Liver function tests should be performed before treatment and periodically thereafter
- Exercise caution when used with drugs affecting steroid hormone synthesis
✔️ Storage:
Store below 30°C, protected from light and moisture. Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
