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Endofree 2.5mg Tablet is an anti-cancer medicine classified as an aromatase inhibitor, primarily used in postmenopausal women to treat breast cancer. Breast cancer cells often depend on estrogen for growth, and Endofree 2.5mg Tablet blocks the aromatase enzyme involved in estrogen production, thus inhibiting cancer cell growth and spread.
It's important to adhere to your doctor's prescribed duration for Endofree 2.5mg Tablet usage. Common side effects may include increased cholesterol levels, fatigue, weakness, sweating, joint pain, and hot flashes. If you experience any persistent side effects, don't hesitate to discuss them with your doctor.
Before taking Endofree 2.5mg Tablet, inform your doctor about any kidney or liver issues, as well as any history of bone problems like osteoporosis or joint pain. This medication is only suitable for postmenopausal women and should be avoided during pregnancy or breastfeeding due to potential harm to the baby.
Endofree 2.5mg Tablet may cause drowsiness and dizziness, so avoid driving if you experience these symptoms. It's not recommended for use in children due to a lack of safety data. Additionally, alcohol consumption with Endofree 2.5mg Tablet may exacerbate drowsiness and dizziness, so it's best to avoid alcohol while taking this medication. Always keep your doctor informed about your health status and any other medications you may be taking to prevent potential interactions or adverse effects.
Consuming alcohol with Endofree does not cause any harmful side effects.
Endofree is highly unsafe to use during pregnancy. Consult your doctor as studies have shown significant harmful effects on the developing baby.
Endofree is unsafe to use during breastfeeding. It may cause toxicity to the baby.
Endofree may decrease alertness, affect vision, or induce sleepiness and dizziness. Avoid driving if experiencing these symptoms.
Use Endofree with caution in patients with liver disease. Dose adjustment may be needed. Consult your doctor.
Endofree is safe to use in patients with kidney disease. No dose adjustment is recommended, but limited information is available for end-stage kidney disease. Consult your doctor.
Letrozole in Endofree Tablet works by reducing the level of a natural female hormone known as oestrogen that is produced in the body. Eventually, stopping the growth of the cancer cells, which depend on oestrogen for its growth.
Breast cancer is characterized by the abnormal growth of cells in the breast tissue, often influenced by estrogen. These cancerous cells can originate in different parts of the breast, including the lobules, ducts, fatty tissue, or fibrous connective tissue. As the cancer progresses, it can invade surrounding healthy breast cells and may spread to nearby lymph nodes, serving as a pathway for further metastasis to other parts of the body.
Common symptoms of breast cancer include the presence of a lump or thickening in the breast tissue, which feels distinct from the surrounding area. Other signs may include breast pain, redness, swelling, abnormal nipple discharge (such as bloody discharge), changes in the shape, size, or appearance of the breast, skin changes like peeling or scaling, and the presence of a lump or swelling under the arm.
Early detection through regular breast self-exams, clinical breast exams, and mammograms can significantly improve outcomes, as breast cancer is most treatable when diagnosed in its early stages. Prompt medical attention should be sought if any concerning symptoms are noticed, as early intervention can lead to more effective treatment and a better prognosis.
Induction of ovulation is a treatment approach used to help women who experience infertility due to issues with ovulation. Ovulation induction involves the use of medications to stimulate the ovaries to release eggs (ovulation) in a controlled manner, increasing the chances of conception.
This treatment is typically recommended for women who have irregular or absent ovulation, which can be caused by various factors such as polycystic ovary syndrome (PCOS), hypothalamic dysfunction, or other hormonal imbalances.
Common medications used for ovulation induction include:
Ovulation induction is usually accompanied by careful monitoring through hormonal assays and ultrasound scans to track follicle development and determine the optimal timing for intercourse or assisted reproductive techniques such as intrauterine insemination (IUI) or in vitro fertilization (IVF).
It's essential for women undergoing ovulation induction to be monitored closely by a fertility specialist to minimize the risk of complications such as multiple pregnancies and ovarian hyperstimulation syndrome (OHSS). Additionally, lifestyle modifications such as maintaining a healthy weight, managing stress, and avoiding smoking can enhance the effectiveness of ovulation induction treatments.
Letrozole inhibits estrogen biosynthesis by binding to the aromatase enzyme, reducing estrogen production in tissues. It suppresses plasma estrogen concentrations in postmenopausal patients with advanced breast cancer.
Recommended dose: 2.5 mg once daily for 5 years in adjuvant and extended adjuvant therapy. In metastatic disease, continue until tumor progression. No dose adjustment is needed for hepatic or renal impairment.
No clinically significant interactions with cimetidine or warfarin were observed.
Hypersensitivity to letrozole, aromatase inhibitors, or ingredients. Contraindicated during pregnancy, lactation, and in severe hepatic dysfunction.
Not recommended during pregnancy or lactation.
Exercise caution in moderate hepatic dysfunction. No dose adjustment is needed for renal impairment. Patients should be aware of potential fatigue and dizziness, affecting driving or machinery operations.
Store below 30°C, away from light and moisture. Keep out of reach of children.
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