Tablet
Manufacturer/Distributor: Eskayef Bangladesh Ltd.
Generic Name: Clomiphene Citrate 50 mg Tablet
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Clomiphene citrate is mainly shown for the treatment of ovulatory disappointment in female patients who wish to ended up pregnant. This treatment will not be fruitful unless the understanding in spite of the fact that unovulatory, is able of ovulation & her accomplice is fertile. Clomiphene citrate is additionally shown for the Polycystic ovary disorder, Menorrhagia caused by hyperplastic endometrium, Amenorrhea with galactorrhea disorder, Psychogenic amenorrhea disorder, Auxiliary amenorrhea of obscure cause, Amenorrhea amid post verbal prophylactic period.
Clomiphene has basically antiestrogenic impacts and a few estrogenic impacts. The component in fortifying ovulation is obscure but is accepted to be related to its antiestrogenic properties. By clomiphene competing with estrogen for official destinations at the hypothalamic level, the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), discharge is expanded, which comes about in ovarian follicle development, taken after by the preovulatory LH surge, ovulation, and the consequent improvement of the corpus luteum. Value in male fruitlessness is additionally likely related to the increments in FSH and LH secretion.
The usual dose for the first course of Clomiphene is 50 mg (1 tablet) a day for 5 days in the early follicular phase of the cycle, following normal menstruation or a progestagen-induced withdrawal bleeding. Many regimes have been used, but most common begin either on day 2 or day 5. If this dose induces ovulation, there is no need to increase the dose in the following courses. If this dose induces ovulation, but pregnancy does not occur, stimulation with Clomiphene Citrate is to be continued, but up to 6 stimulative courses. If the first course does not induce ovulation, the second course should be started with 100 mg a day (2 tablets of 50 mg taken in a single dose) for 5 days. If ovulation is not induced, 2 more stimulative courses of the same dose should be given. If the next three stimulative courses do not produce a successful result, the therapeutic trial is considered to be finished. If ovulation is induced, but pregnancy does not occur, maximum 6 courses with Clomiphene are recommended. However, if menstrual bleeding does not occur, the patient should be examined carefully for the possible pregnancy, and the next course of therapy should be delayed until the correct diagnosis has been determined.
No sedate interaction has been detailed amid the organization of Clomiphene citrate.
Clomiphene citrate is contraindicated amid pregnancy, in patients with liver maladies, ovarian sores, dying of undetermined root, patients with neoplasm of the endometrium.
SSRIs are less sedating than tricyclic antidepressants and have fewer antimuscarinic and cardiotoxic effects. SSRIs can cause gastrointestinal problems (nausea, vomiting, dyspepsia, abdominal pain, diarrhoea, and constipation are all dose-related and fairly common), as well as anorexia and weight loss (increased appetite and weight gain also reported).
The risks and benefits of treating a pregnant woman with Escitalopram during the third trimester should be carefully considered by the physician. It's passed through human breast milk. The risk of citalopram exposure for the infant and the benefits of Escitalopram treatment should be considered when deciding whether to continue or stop nursing or Escitalopram therapy.
In patients with epilepsy (avoid if poorly controlled, discontinue if convulsions develop), concurrent electroconvulsive therapy (prolonged seizures reported with fluoxetine), history of mania, cardiac disease, diabetes mellitus, angle-closure glaucoma, concomitant use of drugs that increase bleeding risk, and history of bleeding disorders, SSRIs should be used with caution.
SSRIs and other antidepressant medications
Protect from light and moisture by storing below 30°C. Keep the medicine out of children's reach.
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