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Tibilon 2.5mg 28pcs Tablets
Tibolone is used for hormone replacement therapy and post-menopausal osteoporosis
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✅ Description:
- Tibolone is a hormonal medication. It has effects similar to estrogen, progesterone, and androgen.
- Tibolone is used as a part of hormone replacement therapy to relieve symptoms of menopause such as hot flashes, vaginal dryness, depression, and night sweats.
- It may also be used for preventing osteoporosis in women who have attained menopause and are at high risk of fractures.
- Take it at the same time every day to help you remember to take it.
- It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.
- Stop taking Tibolone and inform your doctor immediately if you get severe headaches, stabbing pains, or swelling in one leg, and pain breathing. These could be symptoms of a blood clot in a vein.
- Ensure that you regularly check your breasts for any changes and undergo regular breast screening and cervical smear tests while on treatment with this medicine.
- Do not use Tibolone if you have a history of blood clots and liver disease.
Safety Advices
Alcohol
UNSAFE
It is unsafe to consume alcohol with Tibilon 2.5mg Tablet.
Pregnancy
UNSAFE
Tibilon 2.5mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breastfeeding
CONSULT YOUR DOCTOR
Information regarding the use of Tibilon 2.5mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CAUTION
Tibilon 2.5mg Tablet does not usually affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Tibilon 2.5mg Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Tibilon 2.5mg Tablet in patients with liver disease. Please consult your doctor.
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✔️ Uses of Tibilon 2.5
- Post menopausal osteoporosis
- Hormone replacement therapy
✔️ How does Tibilon 2.5 work?
It substitutes for the loss of estrogen production in postmenopausal women and treats menopausal symptoms such as hot flashes, night sweats, and vaginal problems. It also prevents bone loss following menopause.
✔️ Side Effects of Tibilon 2.5
Early treatment months may see vaginal bleeding/spotting. Other effects include headache, migraine, edema, dizziness, pruritus, weight gain, nausea, abdominal pain, rash, and depression.
✔️ Dosage & Administration of Tibilon 2.5
Daily intake of one Tibolone tablet (2.5 mg) swallowed with water or a drink, preferably at the same time daily. Symptom improvement typically occurs within weeks, with optimal results after three months.
Initiating Tibolone Tablet: Natural menopause-treated women should start Tibolone tablets at least 12 months post-last bleed. For surgical menopause, immediate treatment is recommended.
The transition from HRT: For sequential HRT, Tibolone starts a day post-prior regimen. For continuous-combined HRT, Tibolone can begin anytime.
- If within 12 hours, take the missed dose; otherwise, skip it and resume the regular schedule, though this may increase bleeding/spotting risk.
✔️ Indications:
Treatment of symptoms arising from natural or surgical menopause in postmenopausal women. Prevention of osteoporosis in women post-menopause at high fracture risk, unable to take alternative osteoporosis prevention medicines.
✔️ Pharmacology
Tibolone, a synthetic steroid, exhibits estrogenic, androgenic, and progestogenic properties. Rapidly metabolized after oral intake, Tibolone forms three compounds influencing its pharmacological effects. While two metabolites (3α−OH and 3β−OH) display estrogenic activity, a third (δ4-isomer) and the parent compound exhibit progestogenic and androgenic activities. Tibolone substitutes for lost estrogen post-menopause, alleviating menopausal symptoms and preventing bone loss. It affects vaginal, bone, and thermoregulatory centers (e.g., hot flushes) and improves vaginal dryness and atrophy. Tibolone also influences mood and libido.
✔️ Interaction
No reported Tibolone interactions exist, but consider potential interactions like enzyme-inducing compounds enhancing metabolism (e.g., barbiturates, carbamazepine). Tibolone may boost anticoagulant effects.
✔️ Contraindications
Pregnancy, lactation, hormone-dependent tumors, cardiovascular/cerebrovascular disorders, deep vein thrombosis, thromboembolic disorders, unknown vaginal bleeding cause, severe liver disorders.
✔️ Pregnancy & Lactation
Contraindicated during pregnancy/lactation; withdraw treatment if pregnancy occurs.
✔️ Precautions & Warnings
Caution in renal dysfunction, liver disease history, epilepsy, migraine, hypercholesterolemia, impaired carbohydrate metabolism, diabetes mellitus, and cholestatic jaundice.
Tibolone has low acute toxicity, but overdose may induce nausea, vomiting, and withdrawal bleeding in females, treated symptomatically if necessary.
✔️ Storage Conditions:
Store in a cool, dry, light-protected place, away from children's reach.
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