Amlosartan 10/160mg Tablet | Combined Antihypertensive Preparations | 10pcs Price
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Amlosartan 10/160mg Tablet 10pcs

Generic: Amlodipine +Valsartan

Type: Tablet

Pack Size: 10 Pcs

(Amlodipine + Valsartan)-(10 mg+160 mg) is used in the treatment of Hypertension (High Blood Pressure).


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Discount Price: ৳ 84.6
MRP: ৳ 90 6% Off

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✅ Description:

Amlosartan 10/160mg Tablet (Antihypertensive agent) contains a combination of Amlodipine and Valsartan.

  • Treatment of hypertension (high blood pressure) when single-agent therapy is not effective.

Hypertension (High Blood Pressure):

  • A condition where blood force against artery walls is persistently high.
  • May lead to severe damage to vital organ blood vessels (heart, kidney, brain).
  • Complications: heart attack, heart failure, stroke, blindness.
  • Amlosartan 10/160mg Tablet helps lower blood pressure, reducing the risk of heart attack or stroke.

Monitoring during Treatment: Kidney functions, Blood pressure, levels, Blood sugar levels.

  • Eating grapefruit or drinking grapefruit juice. May increase the risk of side effects.
  • Amlosartan 10/160mg Tablet lowers blood pressure to reduce associated risks.
  • Consult a doctor for proper dosage and duration.
  • Regular monitoring during treatment is crucial for safety.
  • Grapefruit consumption should be avoided.

Safety Advices


Alcohol
UNSAFE

Avoid consuming alcohol with Amlosartan 10/160.


Pregnancy
CONSULT YOUR DOCTOR

Unsafe during pregnancy. Consult your doctor for potential risks and benefits in life-threatening situations.


Breastfeeding
CONSULT YOUR DOCTOR

Probably safe during breastfeeding. Limited human data suggests minimal risk.


Driving
CAUTION

May cause side effects (dizziness, headaches). Avoid driving or tasks requiring concentration.


Kidney

Use with caution in severe kidney disease. Regular blood pressure monitoring is recommended. No adjustment is needed in mild to moderate kidney disease.


Liver
CAUTION

Use with caution in liver disease. Dose adjustment may be needed. Consult your doctor.

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✔️ Uses of Amlosartan 10/160mg Tablet

Treatment of high blood pressure.

✔️ How does Amlosartan 10/160mg Tablet work?
  • Amlodipine (Calcium Channel Blocker) and Valsartan (Angiotensin II Receptor Blocker):
    • Relax blood vessels supplying vital organs.
    • Facilitate smoother blood flow, reducing strain on the heart.
    • Promote more efficient pumping with less pressure.
✔️ Side Effects of Amlosartan 10/160mg Tablet
  • Common: Headache, dizziness, ankle swelling, tiredness, palpitations, increased potassium, sleepiness, taste change, flushing, upset stomach.
  • Continuous monitoring for side effects is essential.
✔️ Stop taking the medication and seek immediate medical attention if you experience any of the following:

If you are taking Amlosartan 10/160mg Tablet, it's crucial to be aware of potential serious side effects.

Signs of Allergic Reactions:

  • Skin rash
  • Swelling of the face, lips, mouth, or throat
  • Difficulty in breathing or swallowing

Severe Skin Reactions:

  • Skin rash with itching and redness
  • Blistering and peeling of the skin
  • Skin swelling
  • Inflammation of mucous membranes

Cardiovascular Issues:

  • Chest pain
  • Shortness of breath

Inflammation of Pancreas:

  • Severe stomach pain that radiates to the back
✔️ Quick Suggestions:
  • Amlosartan 10/160mg Tablet provides better blood pressure control.
  • May cause dizziness or sleepiness; avoid tasks requiring focus.
  • Report side effects to the doctor.
  • Avoid alcohol consumption.
  • Consult the doctor if pregnant, planning pregnancy, or breastfeeding.
✔️ Indication of Amlosartan 10/160mg Tablet
  • Combination of Amlodipine and Valsartan to control high blood pressure.
  • Lowers blood pressure by relaxing vessels and aiding heart efficiency.
  • Reduces risk of heart attack or stroke.
✔️ Pharmacology:

Amlodipine:

  • Class: Dihydropyridine Calcium Channel Blocker
  • Action:
    • Inhibits the transmembrane influx of calcium ions.
    • Acts on vascular smooth muscle and cardiac muscle.
    • Results in vasodilation and reduced peripheral vascular resistance.
    • Reduces coronary vasoreactivity and lowers cardiac demand.

Valsartan:

  • Class: Angiotensin II Receptor Blocker (ARB)
  • Action:
    • Blocks vasoconstrictor effects of Angiotensin II.
    • Blocks aldosterone-secreting effects.
    • Selectively inhibits the binding of Angiotensin II to the AT1 receptor.
    • Acts in tissues like vascular smooth muscle and the adrenal gland.
    • Independent of the pathways for Angiotensin II synthesis.

Combined Effects:

  • Blood Pressure Reduction:
    • Both Amlodipine and Valsartan contribute to lowering blood pressure.
    • Amlodipine reduces peripheral resistance through calcium channel blockade.
    • Valsartan blocks the vasoconstrictor effects of Angiotensin II.
    • Complementary mechanisms lead to an enhanced antihypertensive effect.

Understanding the dual mechanism of action helps in achieving effective blood pressure control through vasodilation, reduced vascular resistance, and interference with the renin-angiotensin-aldosterone system.

✔️ Dosage & Administration of Amlosartan 10/160mg Tablet

Dosage Recommendations:

  • Amlodipine: Effective in once-daily doses of 2.5 mg - 10 mg.
  • Valsartan: Effective in doses of 80 mg[1]320 mg.
  • Combination: Amlodipine (5 mg-10 mg) and Valsartan (160 mg[1]320 mg).
  • Antihypertensive effects increase with escalating doses.

Clinical Trials:

  • Antihypertensive effects peak within 2 weeks of initiation or dose adjustment.
  • Dosage can be increased gradually (after 1 to 2 weeks) to a maximum of 10/320 mg once daily for blood pressure control.

Administration:

  • Can be taken with or without food.
  • Can be administered with other antihypertensive agents.

Switching Therapy:

  • Patients not adequately controlled with Amlodipine or Valsartan alone can be switched to this combination therapy.

Elderly Patients:

  • Initiate therapy at a lower dose of Amlodipine (2.5 mg) due to decreased clearance.

Renal Impairment:

  • No initial dosage adjustment for mild or moderate renal impairment.
  • Titrate slowly in patients with severe renal impairment.

Hepatic Impairment:

  • No initial dosage adjustment for mild or moderate liver insufficiency.
  • Titrate slowly in patients with hepatic impairment.
✔️ Interaction

No drug interaction studies have been conducted with the Amlodipine and Valsartan combination, although studies have been conducted with the individual components.

✔️ Contraindications

This combination product is contraindicated in patients who are hypersensitive to any components of this product.

✔️ Pregnancy & Lactation

Pregnancy Category D:

  • Pregnancy category D indicates a potential risk to the fetus based on human data, but the benefits of using the drug in pregnant women may outweigh the risks in certain situations.
  • Both Amlodipine and Valsartan fall under Pregnancy Category D.

Lactation:

  • It is not known whether Amlodipine or Valsartan is excreted in human milk.
  • Due to the potential for adverse effects on the nursing infant, a decision should be made whether to discontinue nursing or discontinue the drug.
  • Healthcare providers should consider the importance of the drug to the mother in this decision-making process.

Note:

  • The safety of Amlodipine and Valsartan during pregnancy and lactation should be thoroughly discussed between the healthcare provider and the patient.
  • Any decisions regarding medication use during pregnancy or lactation should be made in consultation with a healthcare professional, considering the specific circumstances of the individual patient.
✔️ Precautions & Warnings

Avoid Fetal or Neonatal Exposure:

  • Take precautions to avoid exposure during pregnancy or breastfeeding.
  • Discuss with your healthcare provider if you are pregnant or planning to conceive.

Assess for Hypotension:

  • Regularly monitor blood pressure to assess for signs of hypotension.
  • Report any symptoms such as dizziness or lightheadedness to your healthcare provider.

Warn Patients with Severe Obstructive Coronary Artery Disease:

  • Inform patients about the risk of myocardial infarction (heart attack) or increased angina.
  • Seek medical attention if experiencing chest pain or worsening angina symptoms.

Titrate Slowly in Patients with Impaired Hepatic Function:

  • If you have impaired liver function, the dosage should be adjusted carefully.
  • Consult your healthcare provider for appropriate titration.

Titrate Slowly in Patients with Severely Impaired Renal Function:

  • Patients with severe renal impairment should undergo slow titration of the medication.
  • Regular monitoring and adjustments may be necessary.
✔️ Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Frequently Asked Questions (FAQ)

Treatment of hypertension in adults.

Antihypertensive combination (Amlodipine + Valsartan).

Do not stop without consulting; blood pressure may rise. Take as per the prescribed duration for optimal results

Take missed dose if remembered; else, skip and resume regular schedule.

Timing personalized based on age, weight, and condition.
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Check our pricing section for Amlosartan 10/160mg Tablet 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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