Tablet, Manufacturer/Distributor: Aristopharma Limited, Generic Name: Bisoprolol Hemifumarate 5 mg + Hydrochlorothiazide 6.25 mg Tablet
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Indications of Ancor 2.5 Tablet
Bisoprolol is used to treat hypertension and angina. Heart failure ranges from mild to severe.
Pharmacology of Ancor 2.5 Tablet
The most selective ß1 blocker is Bisoprolol Hemifumarate. It has the highest affinity for the ß1 receptor of any beta-blocker currently on the market. Blocks the ß1 adrenergic receptor in the heart and vascular smooth muscle, lowering heart rate and cardiac output and lowering arterial blood pressure. In patients with non-ß1 selective ß1-blockers, ß-blockers can impact lipid metabolism, however Bisoprolol does not produce any changes in the cholesterol fraction, including the cardioprotective HDL-cholesterol, over long-term medication.
Dosage and Administration of Ancor 2.5 Tablet
Hypertension: The dose of Bisoprolol must be individualized to the needs of the patient. The usual starting dose is 5 mg once daily. In some patients, 2.5 mg may be an appropriate starting dose. If the antihypertensive effect of 5 mg is inadequate, the dose may be increased to 10 mg and then, if necessary, to 20 mg once daily.
Angina: Usually 10 mg once daily (5 mg may be adequate in some patients) max 20 mg daily.
Heart Failure: Initially 1.25 mg once daily (in the morning) for 1 week then, if well tolerated, increased to 2.5 mg once daily for 1 week, then 3.75 mg once daily for 1 week, then 5 mg once daily for 4 weeks, then- 7.5 mg once daily for 4 weeks, then 10 mg once daily maximum 10 mg daily.
Interaction of Ancor 2.5 Tablet
Other ß-blocking medications should not be taken with bisoprolol.
Contraindications
Right ventricular failure secondary to pulmonary hypertension and sinus bradycardia in individuals with cardiogenic shock, overt heart failure, second or third degree A-V block, and sinus bradycardia.
Side Effects of Ancor 2.5 Tablet
It is possible to experience gastrointestinal disorders, bradycardia, hypotension, headache, fatigue, sleep disturbances, dizziness, vertigo, thrombocytopenia, vision disturbances, and alopecia.
Pregnancy & Lactation
Bisoprolol's safety during pregnancy has yet to be determined. Lactation data isn't available.
Precautions & Warnings
During long-term bisoprolol medication, renal, hepatic, and hematologic function should be monitored at regular intervals.
Storage Conditions
Store in a cool, dry location. Keep out of children's reach.
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