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Bisopro 2.5 Plus (30pcs Box)
Bisoprolol Fumarate 2.5mg + Hydrochlorothiazide 6.25mg is used for treating hypertension (high blood pressure). Both Bisoprolol Fumarate and Hydrochlorothiazide have been proven effective in treating hypertension individually and in combination. Their antihypertensive effects are additive, with Hydrochlorothiazide 6.25 mg significantly enhancing the antihypertensive effect of Bisoprolol Fumarate. The combination also reduces the risk of hypokalemia compared to Hydrochlorothiazide 25 mg alone.
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✅ Description:
Bisopro 2.5 Plus is a combination of Bisoprolol and Hydrochlorothiazide. Bisoprolol belongs to the group of medicines called Beta blockers, while Hydrochlorothiazide belongs to the group of medicines called Thiazide diuretics. It is primarily used to treat hypertension, a condition characterized by consistently high blood pressure against the walls of the arteries.
- Take this medicine with or without food.
- Before taking Bisopro 2.5 Plus, inform your doctor if you are pregnant or breastfeeding.
- Inform your doctor about any kidney, liver, lung, or heart problems you have, as well as other conditions such as diabetes, thyroid problems, psoriasis, metabolic acidosis, non-melanoma skin cancer, or altered electrolyte levels.
- Not recommended for children and adolescents under 18 years of age.
- Inform your doctor about any other medicines you are taking for other conditions or if you have a history of drug allergies to prevent interactions and serious side effects.
- Consult your doctor if your symptoms worsen over time.
Always follow your doctor's instructions and recommendations when taking Bisopro 2.5 Plus.
Safety Advices
Alcohol
Consumption of alcohol is not recommended during treatment with Bisopro 2.5 Plus Tablet, as it may increase the risk of orthostatic hypotension (dizziness upon standing up from a sitting or lying position).
Pregnancy
- Bisopro 2.5 Plus Tablet is not recommended for use during pregnancy due to the potential risks it poses to both the mother and the unborn child. These risks include increased chances of miscarriage, premature birth, impaired growth of the baby, low blood sugar levels, and decreased heart rate in the newborn.
- Consult your doctor for advice before taking Bisopro 2.5 Plus Tablet if you are pregnant.
Breastfeeding
- Bisopro 2.5 Plus Tablet is not recommended for use in breastfeeding women as it may pass into breast milk and harm the nursing infant.
- Consult your doctor for advice before taking Bisopro 2.5 Plus Tablet if you are breastfeeding.
Driving
- Avoid driving or operating machinery if you experience tiredness, dizziness, or drowsiness while taking Bisopro 2.5 Plus Tablet, as it may impair your ability to perform these tasks.
- Consult your doctor for advice before taking Bisopro 2.5 Plus Tablet if you need to drive or operate machinery.
Kidney
- Bisopro 2.5 Plus Tablet is not recommended for use in patients with severe kidney impairment, characterized by low urine output or absence of urine output.
- Consult your doctor for advice before taking Bisopro 2.5 Plus Tablet if you have kidney problems.
Liver
- Use Bisopro 2.5 Plus Tablet with caution in patients with mild to moderate liver impairment.
- It is not recommended for use in patients with severe liver impairment, including hepatic precoma and coma.
- Consult your doctor for advice before taking Bisopro 2.5 Plus Tablet if you have liver problems.
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✔️ Uses of Bisopro 2.5 Plus Tablet
Hypertension (high blood pressure)
✔️ How does Bisopro 2.5 Plus Tablet work?
Bisopro Plus 2.5 combines Bisoprolol (a beta blocker) and Hydrochlorothiazide (a diuretic) to lower blood pressure. Bisoprolol improves heart efficiency, while Hydrochlorothiazide removes excess water from the body and relaxes blood vessels.
✔️ Side Effects of Bisopro 2.5 Plus Tablet
Common side effects include fatigue, dizziness, headache, bradycardia, arrhythmia, gastrointestinal disturbances, and cold extremities. Most side effects are mild and transient.
✔️ Quick Suggestions:
- Combination medication for high blood pressure.
- Take with or without food.
- Don't stop suddenly; it may raise blood pressure.
- May cause dizziness; rise slowly from sitting or lying position.
- Monitor blood sugar if diabetic; may hide symptoms of low blood sugar.
- Drink plenty of fluids to prevent dehydration.
✔️ Indication of Bisopro 2.5 Plus Tablet
Bisopro Plus 2.5 is used to treat hypertension. It combines two medicines to control blood pressure and reduce the risk of heart attack and stroke. Take it as prescribed, even if you feel well. Common side effects include nausea, constipation, and fatigue. Monitor blood pressure, kidney function, and electrolyte levels regularly. Inform your doctor of all medications you're taking and report any side effects promptly.
✔️ Pharmacology
Bisoprolol Fumarate is a selective β1-blocker without significant intrinsic sympathomimetic activity. Hydrochlorothiazide is a thiazide diuretic that acts on renal tubular mechanisms to increase sodium and chloride excretion, thereby reducing blood volume and pressure.
✔️ Dosage & Administration of Bisopro 2.5 Plus Tablet
The combination is available in various strengths. Initial therapy usually starts with a low dose (e.g., one 2.5/6.25 mg tablet) taken orally once daily. The dosage may be titrated gradually based on clinical response and tolerability, up to the maximum recommended dose of 20/12.5 mg once daily.
✔️ Interaction
Bisopro Plus may potentiate the effects of other antihypertensive agents. It should not be used concurrently with other beta-blockers. Close monitoring is required when used with catecholamine-depleting drugs, clonidine, myocardial depressants, or inhibitors of AV conduction.
✔️ Contraindications
The medication is contraindicated in patients with certain cardiac conditions, marked sinus bradycardia, anuria, and hypersensitivity to its components or sulfonamide-derived drugs.
✔️ Pregnancy & Lactation
Use during pregnancy (Category C) or breastfeeding is only recommended if the potential benefits outweigh the risks to the fetus or infant. Caution is advised due to limited data on its safety during lactation.
✔️ Precautions & Warnings
Special precautions are needed in patients with hyperuricemia, acute gout, or electrolyte imbalances. Withdrawal of therapy should be gradual. Overdose may lead to symptoms such as bradycardia, hypotension, and electrolyte disturbances.
✔️ Storage Conditions
Store below 30°C, away from light and moisture, and keep out of reach of children.
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