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Bisoren 2.5 Tablet 1 Strip
đĻ Each tablet contains Bisoprolol Fumarate 5mg or as prescribed
đŠē Therapeutic Class: Selective β1-blocker
đ Manufactured by: Renata Limited
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â Description:
Bisoren 2.5
- High Blood Pressure (Hypertension)
- Chest Pain from Heart Disease (Angina Pectoris)
- Moderate to Severe Heart Failure (with reduced ejection fraction)
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âī¸ Pharmacology Highlights:
- Ultra-selective Ã1-blocker: Bisoprolol offers the highest affinity for Ã1-receptors among beta-blockers.
- Heart-focused action: Reduces heart rate & cardiac workload â lowers blood pressure & anginal symptoms.
- Metabolically neutral: Long-term use does not negatively impact cholesterol, including HDL.
- Once-daily dosing: Thanks to excellent absorption (>90%), minimal first-pass metabolism, and a 10â12 hour half-life.
âī¸ Common Side Effects:
- Fatigue, dizziness, headache
- Gastrointestinal upset: nausea, vomiting, constipation, diarrhea
- Cold hands/feet, muscle cramps
- Respiratory issues in asthma/COPD patients
âī¸ Dosage & Administration:
- Adults: Start with 5 mg once daily. Adjust gradually (up to 20 mg/day max).
- Elderly: Usually no adjustment needed unless impaired liver/kidney function.
- Renal/Hepatic Impairment: Start low (5 mg/day). Titrate cautiously.
- Children: Not established.
đ Dose adjustment interval: 2 weeks
âī¸ Important Interactions:
- Avoid combining with other beta-blockers.
- Caution with clonidine, calcium channel blockers (verapamil, diltiazem), antiarrhythmics, or catecholamine-depleting drugs.
- Monitor for excessive heart suppression or hypotension in combination therapy.
âī¸ Contraindications:
- Cardiogenic shock
- Advanced AV block (2nd/3rd degree)
- Uncontrolled heart failure
- Severe bradycardia or pulmonary hypertension-related RV failure
âī¸ Pregnancy & Lactation:
Pregnancy: Use only if clearly needed. Animal studies show fetal risk at high doses.
Lactation: Unknown if excreted in human milk; breastfeeding should be discontinued if necessary.
âī¸ Precautions:
- Use caution in patients with renal/hepatic impairment
- Patients with a history of severe allergic reactions may have reduced response to epinephrine
- Avoid abrupt withdrawal
âī¸ Storage:
Store in a cool, dry place away from light and heat. Keep out of childrenâs reach.
â ī¸Disclaimer:
At ePharma, weâre committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
