Olmesartan (Medoxomil + Amlodipine) (5mg + 20mg) is used in the treatment of Hypertension (high blood pressure).
🛒 How to order this item?
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
Show More
It is unsafe for you to consume alcohol while on treatment with Bizoran 5/20mg Tablet, as it may worsen your side effects.
Bizoran 5/20mg Tablet is not recommended for use during pregnancy as it can harm your fetus.
Bizoran 5/20mg Tablet is not recommended for use while breastfeeding as it is not known if this medicine passes into breast milk. Consult your doctor if you are breastfeeding.
Avoid driving vehicles or operating machines and rise up slowly from a sitting or lying position if you feel dizzy during treatment with Bizoran 5/20mg Tablet.
ZEST AM 20MG TABLET is not recommended for use in patients with impaired kidney function and should be used with caution in patients with kidney problems or with a surgical history of a kidney transplant. Consult your doctor before taking Bizoran 5/20mg Tablet.
EZEST AM 20MG TABLET is not recommended for use in patients with severe liver problems (such as biliary obstruction, gall stones, and jaundice) and should be used with caution in patients with liver disease. Consult your doctor before taking Bizoran 5/20mg Tablet.
Bizoran 5/20mg Tablet is a combination of Amlodipine and Olmesartan. Amlodipine works by relaxing your heart muscles and blood vessels so that blood can flow more easily. Olmesartan relaxes and widens your blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood throughout your body.
Bizoran 5/20mg Tablet is an angiotensin 2 receptor blocker (ARB) used to treat high blood pressure. It can be taken once daily, with or without food, as directed by your physician. Maintaining optimal blood pressure levels is important for preventing kidney disorders, strokes, and heart disorders. Please follow your doctor's instructions carefully when taking this medication.
Amlodipine is a calcium channel blocker that works by inhibiting the entry of calcium ions into vascular smooth muscle and myocardium. This leads to vasodilation of peripheral arteries, reducing peripheral vascular resistance and lowering blood pressure. Its effect on vascular smooth muscle is greater than its effect on cardiomyocytes.
Angiotensin II is a potent vasoconstrictor and a key hormone in the renin-angiotensin system. It is formed from angiotensin I by the action of angiotensin-converting enzyme (ACE). Angiotensin II also stimulates the release of aldosterone from the adrenal cortex. Aldosterone promotes sodium and water retention, leading to increased blood volume and elevated blood pressure.
Olmesartan Medoxomil is an angiotensin II receptor blocker (ARB) that selectively blocks the binding of angiotensin II to AT1 receptors found in various tissues, including vascular smooth muscle and the adrenal glands. By blocking the vasoconstrictive and aldosterone-secreting effects of angiotensin II, olmesartan Medoxomil helps to relax and dilate blood vessels, reducing peripheral vascular resistance and lowering blood pressure. Unlike ACE inhibitors, olmesartan Medoxomil does not inhibit ACE, the enzyme responsible for converting angiotensin I to angiotensin II and breaking down bradykinin.
In summary, Amlodipine and Olmesartan Medoxomil work together to lower blood pressure by different mechanisms. Amlodipine inhibits calcium entry into vascular smooth muscle, leading to vasodilation, while olmesartan Medoxomil blocks the vasoconstrictive and aldosterone-secreting effects of angiotensin II by selectively blocking its binding to AT1 receptors.
The recommended initial dose of Bizoran 5/20mg Tablet for hypertension is 5 mg amlodipine and 20 mg olmesartan once daily. The dose may be increased after 1-2 weeks of treatment if needed, but the maximum recommended dose is 10 mg amlodipine and 40 mg olmesartan. It can be taken alongside other antihypertensive agents.
For elderly patients, a lower starting dose may be considered. In patients with mild to moderate hepatic impairment, caution should be exercised.
It is important to follow your physician's instructions and take Bizoran 5/20mg Tablet as prescribed. Swallow the tablet whole with a glass of water and do not crush or chew it. The dose and duration of treatment will be determined by your doctor based on factors such as your age, body weight, and the specific condition being treated.
Bizoran 5/20mg Tablet may interact with various medications and substances. Some of the drug-drug interactions include interactions with high blood pressure medications, lipid-lowering drugs, medications for erectile dysfunction, antibiotics, antifungal drugs, anti-HIV drugs, anti-epilepsy medications, immune-suppressing drugs, and painkillers. It is important to inform your doctor about all the medications you are taking, including over-the-counter drugs and supplements, to avoid potential interactions.
There are also drug-food interactions to be aware of. Grapefruit, grapefruit juice, and St. John's wort should be avoided while taking Bizoran 5/20mg Tablet as they can interact with the medication.
In terms of drug-disease interactions, Bizoran 5/20mg Tablet should not be given to individuals with cardiogenic shock, heart valve problems (stenosis), low blood pressure (hypotension), liver disease, or heart failure. It is important to discuss your medical history and any underlying conditions with your doctor before starting this medication.
Pregnancy category D. The combination of Amlodipine and Olmesartan Medoxomil should not be used in the second and third trimesters as it can cause fetal death. When pregnancy is detected, this combination should be stopped as soon as possible. It is not clear whether olmesartan and amlodipine are excreted in human milk. Due to the possible adverse effects of breastfeeding babies, the decision should be based on the importance of the drug to the mother whether to stop breastfeeding or to stop taking the drug.
Store at room temperature away from light and moisture. Do not store it in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.