Epleron 25mg 10pcs - ePharma
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Epleron 25mg 10pcs

Generic: Eplerenone INN 25mg

Type: Tablet

Pack Size: 10 Pcs

Incepta Pharmaceuticals Ltd.

Generic: Eplerenone 25mg


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Discount Price: ৳ 282
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✅ Description:

Indications of Epleron 25

A drug called Epleron 25 is classified as a diuretic (water pill). It is primarily used to treat excessive blood pressure and heart failure. Additionally, it's utilized to lessen swelling (edema) brought on by a few other disorders.

Pharmacology

Eplerenone specifically ties to the mineralocorticoid receptor and pieces the authority of aldosterone, a key component within the renin-angiotensin-aldosterone system, which is included within the direction of BP and the pathophysiology of CV infection. Aldosterone ties to mineralocorticoid receptors in both epithelial (e.g. kidney, GI tract) and nonepithelial (e.g. heart, blood vessels, brain) tissues; causing increments in BP by actuating Na reabsorption, vascular renovating, water maintenance, endothelial brokenness and conceivably other components.

Dosage & Administration

Congestive Heart Failure after an acute Myocardial Infarction: The recommended dose of Eplerenone is 50 mg once daily. Treatment should be initiated at 25 mg once daily and titrated to the target dose of 50 mg once daily preferably within 4 weeks as tolerated by the patient. Eplerenone may be administered with or without food.

Hypertension: Eplerenone may be used alone or in combination with other antihypertensive agents. The recommended starting dose of Eplerenone is 50 mg administered once daily. For patients with an inadequate blood pressure response to 50 mg once daily the dosage of Eplerenone should be increased to 50 mg twice daily. Higher dosages of Eplerenone are not recommended either because they have no greater effect on blood pressure than 100 mg or because they are associated with an increased risk of hyperkalemia.

Interaction of Epleron 25

ACE drugs and/or angiotensin receptor blockers, ciclosporin, tacrolimus, and trimethoprim may raise the risk of hyperkalemia. NSAIDs, glucocorticoids, and tetracosactide may diminish the antihypertensive impact. TCAs, amifostine, baclofen, and neuroleptics may augment the hypotensive impact of 1-blockers (e.g. alfuzosin, prazosin), TCAs, amifostine, baclofen, and neuroleptics. Mild to moderate CYP3A4 inhibitors may cause an increase in plasma levels.

Contraindications

Eplerenone is contraindicated in-

Hyperkalaemia

Severe renal impairment (creatinine clearance less than 30 ml/min)

Severe hepatic impairment

Concomitant use with potent CYP3A4 inhibitors like Ketoconazole, Itraconazole, Nefazodone, Troleandomycin, Clarithromycin, Ritonavir, and Nelfinavir or other

Potassium-sparing diuretics are also contraindicated

 

Side Effects of Epleron 25

It is possible to get headaches, dizziness, diarrhea, stomach pain, nausea, cough, or flu-like symptoms. Rashes, itching, swelling, extreme dizziness, and problems breathing are all symptoms of a significant allergic reaction.

 

Pregnancy & Lactation

Pregnancy: There are no satisfactory and well-controlled ponders in pregnant ladies. Eplerenone ought to be utilized amid pregnancy as it were in case the potential advantage legitimizes the potential hazard to the fetus.

Lactation: The concentration of Eplerenone in human breast drain after the verbal organization is obscure. Since numerous drugs are excreted in the human drain and since of the obscure potential for unfavorable impacts on the nursing newborn child, a choice ought to be made whether to cease nursing or cease the sedate, taking into consideration the significance of the sedate to the mother.

Precautions & Warnings

In hyperkalemia, severe kidney disease, and diabetic patients with congestive heart failure following an acute myocardial infarction, especially those with proteinuria, eplerenone should be taken with caution.

Storage Conditions

Store at or below 30°C in a cool, dry location away from light and moisture. Keep out of reach of youngsters.

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Check our pricing section for Epleron 25mg 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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