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Pendoril 4mg Tablet 10pcs
Pendoril 4 is an ACE inhibitor, reducing stress on the heart and relaxing blood vessels for smoother blood flow.
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✅ Description:
Perindopril Erbumine is a medication prescribed for the treatment of high blood pressure (hypertension), and heart failure, and is often recommended after a heart attack. It belongs to a class of drugs known as ACE (angiotensin-converting enzyme) inhibitors.
- Reduces the risk of future strokes and heart attacks
- Improves survival post-heart attack or heart surgery
- Lowers blood pressure and eases the heart's pumping action
- Available only on prescription
- Takes a few hours to start working, with full effect taking a few weeks
- The first dose may cause dizziness, recommended to take it at bedtime initially
- If no dizziness occurs, subsequent doses can be taken in the morning before breakfast
- Some individuals may experience a dry, tickly cough
- If persistent, the doctor may suggest switching to a different medicine
- Severe diarrhea or vomiting due to illness may require stopping perindopril temporarily. Consult with the doctor in such situations
- Alcohol can enhance the blood pressure-lowering effect, leading to dizziness or lightheadedness
- It is advisable to avoid alcohol until the individual understands how perindopril affects them
- Perindopril can be referred to as perindopril arginine, perindopril erbumine, or perindopril tert-butylamine.
- All these forms are equally effective and contain the same amount of perindopril.
Safety Advices
Alcohol
UNSAFE
Pendoril 4 may cause excessive drowsiness when consumed with alcohol.
Pregnancy
UNSAFE
Pendoril 4 is considered unsafe during pregnancy due to potential risks to the developing baby. However, in life-threatening situations, the doctor may prescribe it if the benefits outweigh the risks. Consult your doctor for advice.
Breastfeeding
CONSULT YOUR DOCTOR
Pendoril 4 is probably safe during breastfeeding. Limited data suggests no significant risk to the baby. However, consult with your doctor before use.
Driving
CAUTION
Pendoril 4 may cause side effects affecting driving. While it usually doesn't impact alertness, dizziness or weakness may occur in some patients, affecting driving ability.
Kidney
CONSULT YOUR DOCTOR
Use Pendoril 4 with caution in patients with kidney disease. Dose adjustment may be necessary. Consult your doctor, especially if you have renal impairment.
Liver
CONSULT YOUR DOCTOR
Use Pendoril 4 with caution in patients with liver disease. Dose adjustment may be necessary. Inform your doctor of any signs of jaundice.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Uses of Pendoril 4mg Tablet
- Hypertension (high blood pressure)
- Prevention of heart attack and stroke
- Heart failure
✔️ How does Pendoril 4mg Tablet work?
Perindopril is an ACE inhibitor, blocking the action of angiotensin-converting enzyme (ACE). This leads to a reduction in angiotensin II production, allowing blood vessels to relax and widen, resulting in a drop in blood pressure.
✔️ Side Effects of Pendoril 4mg Tablet
- Rare and Mild: Cough, fatigue, asthenia, headache, disturbances of mood and/or sleep.
- Less Often: Taste impairment, epigastric discomfort, nausea, abdominal pain, and rash.
- Reversible Increase: Blood urea and creatinine.
- Proteinuria: Occurred in some patients.
- Rarely: Angioneurotic edema, decrease in hemoglobin, red cells, and platelets.
✔️ Quick Suggestions:
- Rise slowly due to initial dizziness.
- Report persistent cough or throat irritation.
- Avoid potassium supplements and rich foods.
- Inform the doctor if pregnant, planning pregnancy, or breastfeeding.
✔️ Indication of Pendoril 4mg Tablet
- High blood pressure (hypertension)
- Heart failure
- Post-heart attack therapy to reduce the risk of future strokes and heart attacks
✔️ Pharmacology
Perindopril, a long-acting ACE inhibitor, is indicated in essential hypertension, stable coronary artery disease, and congestive heart failure.
✔️ Dosage & Administration of Pendoril 4mg Tablet
- Hypertension: One Perindopril 4 tablets once daily in the morning. The dose may be increased to 8 mg after 1 month if necessary.
- Stable Coronary Artery Disease: Perindopril 4 once daily for two weeks, then increased to 8 mg once daily. Elderly patients may start with 2 mg and titrate.
- Congestive Heart Failure: Start with 2 mg in the morning, may increase to 4 mg if necessary. Caution in elderly patients, start at a low daily dose.
✔️ Interaction
- May enhance the hypotensive effect with diuretics.
- Additive hyperkalaemic effect with K supplements, K-sparing diuretics, and other drugs.
- Increased serum levels and toxicity of lithium.
- Antihypertensive effects may be reduced by aspirin or other NSAIDs.
- Coadministration with NSAIDs may increase the risk of renal impairment.
- Increased risk of hypoglycemia with antidiabetic agents.
- Rare nitritoid reactions with concomitant use of gold (Na aurothiomalate).
✔️ Contraindications
- Hypersensitivity to Perindopril.
- Contraindicated in children, during pregnancy, and lactation.
✔️ Pregnancy & Lactation
Perindopril should not be used during pregnancy and lactation.
✔️ Precautions & Warnings:
- Use with caution in renovascular hypertension, surgery/anesthesia, and renal failure.
- Adjust the dose cautiously per creatinine clearance.
- Symptomatic hypotension is rare but more likely in volume-depleted patients.
- Stop diuretic 3 days before starting Perindopril in diuretic-treated patients.
✔️ Storage Conditions
- Keep below 30°C temperature, away from light and moisture.
- Keep out of the reach of children.
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lab tests, medicines, all possible side effects, drug interactions,
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