Tems A 40/5mg Tablet | 10 pcs | 20pcs | 30pcs
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Tems A 40/5mg Tablet 1 Strip

Generic: Amlodipine + Telmisartan

Type: Tablet

Pack Size: 10 Pcs

Tems A is a fixed-dose combination of Telmisartan and Amiodipine.

  • Telmisartan is an angiotensin II receptor blocker (ARB) that selectively blocks the AT1 receptor, preventing the vasoconstrictor and aldosterone-secreting effects of angiotensin II. This leads to blood vessel dilation and reduced blood pressure without affecting pulse rate.
  • Amlodipine is a calcium-channel blocker (CCB) that inhibits calcium influx into vascular smooth muscle and cardiac muscle, leading to reduced peripheral vascular resistance and lower blood pressure.

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✅ Description:

Pack Image of Tems A 5 mg Tablet
Tems A is used for the treatment of hypertension, either alone or in combination with other antihypertensive agents. It is also suitable as an initial therapy in patients who may require multiple medications to reach their blood pressure targets.
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✔️ Dosage & Administration:
  • Initial Therapy: Typically, start with 40/5 mg once daily if blood pressure control with a single agent is unlikely. For larger blood pressure reductions, 80/5 mg once daily may be used. Not recommended for patients 75 years or older or those with hepatic impairment.
  • Add-on Therapy: For patients inadequately controlled on Amiodipine or Telmisartan alone, this combination can be added.
  • Replacement Therapy: For patients already taking separate Telmisartan and Amlodipine tablets, this combination may be used in place of those. The dose may be adjusted after at least 2 weeks, with a maximum of 80/10 mg once daily.
  • Pediatric use: Safety and efficacy have not been established.
  • Geriatric use: Not recommended for patients ≥75 years old.
  • Hepatic impairment: Not recommended for those with hepatic impairment.
✔️ Side Effects:

Common side effects include dizziness, peripheral edema, headache, fatigue, abdominal pain, nausea, diarrhea, pruritus, erectile dysfunction, chest pain, and bradycardia.

✔️ Interaction
  • No clinically significant interactions with acetaminophen, amiodipine, glyburide, simvastatin, hydrochlorothiazide, warfarin, or ibuprofen.
  • Telmisartan does not significantly affect cytochrome P450 enzymes.
  • Amlodipine has no clinically relevant effects when taken with cimetidine, grapefruit juice, or sildenafil and is safe with a variety of other medications including thiazide diuretics and beta-blockers.
✔️ Contraindications:
  • Known hypersensitivity to any of its components.
  • Pregnancy and lactation.
  • Severe hepatic impairment, biliary obstructive disorders, hypotension, cardiogenic shock, and left ventricle outflow tract obstruction.
✔️ Pregnancy & Lactation:
  • Category C in the first trimester and Category D in the second and third trimesters.
  • The safety of this combination during breastfeeding is not known. Discontinue breastfeeding or the drug after considering its importance to the mother.
✔️ Precautions & Warnings:
  • Avoid fetal or neonatal exposure.
  • Correct volume or salt depletion before initiating therapy.
  • Monitor for worsening heart failure.
  • Do not combine with ACE inhibitors and angiotensin receptor blockers.
  • Monitor for myocardial infarction risk in patients with severe coronary artery disease.
✔️ Overdose Effects:
  • Telmisartan: May cause hypotension, dizziness, and tachycardia. Treat with supportive care.
  • Amlodipine: Overdose may lead to excessive vasodilation, hypotension, and reflex tachycardia. Cardiovascular support and vasopressors may be required.
✔️ Storage:

Store below 30°C, and protect from light and humidity. Keep out of reach of children.

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Check our pricing section for Tems A 40/5mg Tablet 1 Strip price in Bangladesh. After Submitting Order, You may receive phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

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