Azithromycin is used in the treatment of Bacterial infections. It is used in bacterial infections of the tonsils, sinus, ear, nose, throat, skin and soft tissues, and lungs (pneumonia).
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Acos 500mg Tablet is a macrolide antibiotic used to treat various bacterial infections in the respiratory system, skin, ears, and sexually transmitted infections. It works by inhibiting the production of proteins required by bacteria for their survival.
Here are some key points to remember:
Remember to consult your doctor for specific instructions and advice regarding the use of Acos 500mg Tablet in your individual case.
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
There is insufficient information available about the use of Acos 500mg Tablet during pregnancy. Therefore you should not use Acos 500mg Tablet during pregnancy unless explicitly advised by your doctor.
Acos 500mg Tablet 5's is partially passed through the mother’s milk, therefore it should not be used if you are breastfeeding.
The side effects of Acos 500mg Tablet can be adverse and when facing the same, driving should be completely avoided.
Caution must be taken while taking this medication in patients with kidney disease. Adjustment of the dose is required, thus consult your doctor before taking Acos 500mg Tablet.
Acos 500mg Tablet should be avoided if the person is suffering from any type of liver disease.
Acos 500mg Tablet is a bacteriostatic drug, which means it slows down or inhibits the growth and reproduction of bacteria. It achieves this by binding to the 50S ribosomal subunits of susceptible microorganisms, thereby interfering with protein synthesis. This disruption in protein synthesis impairs the ability of the bacteria to function and reproduce effectively, leading to their inhibition and eventual elimination by the body's immune system.
Acos 500mg Tablet is used to treat a variety of mild to moderate susceptible infections caused by bacteria and other microorganisms. Some of the conditions it can treat include:
Azithromycin, the active ingredient in Acos 500mg Tablet, acts by binding to the 50S ribosomal subunit of susceptible microorganisms, thereby interfering with microbial protein synthesis. It does not affect nucleic acid synthesis. The medication has demonstrated activity against various microorganisms, both in vitro and in clinical infections. These include:
Aerobic and facultative gram-positive microorganisms:
Aerobic and facultative gram-negative microorganisms:
Other microorganisms:
Here are the recommended dosage guidelines for Acos 500mg Tablet:
Oral administration in adults:
Oral administration in children:
For typhoid fever: Take 500 mg (2½ teaspoonfuls) once daily for 7-10 days.
Azithromycin Injection (For IV Infusion only):
It is important to follow your physician's advice regarding the correct dose and duration of treatment based on your age, body weight, and specific disease condition. Take the medicine with a glass of water and do not crush or chew it. The safety and effectiveness of Azithromycin for injection in children or adolescents under 16 years have not been established.
Interaction with Alcohol: The interaction between Acos 500mg Tablet and alcohol is unknown. It is advisable to consult your doctor before consuming alcohol while taking this medication.
Interaction with Lab Tests: Monitoring of liver function tests and complete blood count (CBC) with differential may be necessary while taking this medicine.
Interaction with Other Medications: Acos 500mg Tablet may inhibit the CYP3A3/4 enzyme, which can affect the metabolism of certain drugs. It can also increase the levels of medications such as tacrolimus, phenytoin, ergot alkaloids, alfentanil, astemizole, terfenadine, bromocriptine, carbamazepine, cyclosporine, digoxin, disopyramide, and triazolam. However, Azithromycin did not affect the response to warfarin or theophylline. Caution is advised when administering these medications together.
Interaction with Specific Diseases: Acos 500mg Tablet may have interactions with certain diseases such as QT prolongation, liver disease, and myasthenia gravis. It is important to inform your doctor if you have any of these conditions before taking the medication.
Use in Patients with Hepatic Dysfunction: Acos 500mg Tablet should be used with caution in patients with hepatic dysfunction, as it may cause liver impairment. Symptoms such as malaise, nausea, vomiting, abdominal colic, and fever may occur, and if they do, the use of the medication should be discontinued.
Masking Symptoms of Infections: Acos 500mg Tablet may mask or delay the symptoms of incubating gonorrhea or syphilis. Therefore, appropriate culture and susceptibility tests should be performed before initiating the medication.
Pseudomembranous Colitis: There have been reports of pseudomembranous colitis associated with the use of macrolide antibiotics, including Acos 500mg Tablet. If you experience severe diarrhea while taking this medication, inform your doctor.
Interaction with Food: The rate and extent of gastrointestinal absorption of Acos 500mg Tablet may be decreased when taken with food. It is recommended to take this medicine on an empty stomach for optimal absorption.
Remember to always follow your doctor's instructions and inform them about any other medications or health conditions you have to avoid potential interactions and ensure the safe and effective use of Acos 500mg Tablet.
Acos 500mg Tablet is contraindicated in patients hypersensitive to Azithromycin or any other macrolide antibiotic. Co-administration of ergot derivatives and Azithromycin is contraindicated. Acos 500 mg Tablet is contraindicated in patients with hepatic diseases.
Azithromycin, the active ingredient in Acos 500mg Tablet, is classified as Pregnancy Category B. Animal studies have not shown evidence of harm to the fetus, but there are no adequate and well-controlled studies in pregnant women. Therefore, the use of Acos 500 mg Tablet during pregnancy should be considered only if there are no suitable alternatives available.
The presence of Azithromycin in breast milk is not known. Caution should be exercised when Acos 500 mg Tablet is administered to nursing women. It is important to weigh the potential benefits of treatment with Azithromycin against any potential risks to the breastfeeding infant. Women should monitor their breastfed infants for any signs of adverse effects such as diarrhea, vomiting, or rash.
Store Acos 500mg Tablets at room temperature in a cool and dry place. Keep out of the reach of children & pets.
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