This medication is used to treat certain parasitic roundworm infections.
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Alice 6mg Tablet contains Ivermectin, which is classified as an Antiparasitic agent. It is primarily used to treat various parasitic infections, including:
Before taking Alice 6mg Tablet, it's important to inform your doctor if you have conditions such as loa infection (a type of eye infection) or a weakened immune system, and if you're taking any other medications for different conditions.
Pregnant and breastfeeding women should generally avoid using Alice 6mg Tablet unless specifically advised by their doctor. It's essential to consult with a healthcare professional before taking this medication.
The safety and efficacy of Alice 6mg Tablet in children weighing less than 15 kg have not been adequately evaluated. Additionally, caution should be exercised when administering this medication to elderly patients aged 65 years and above.
Common side effects of Alice 6mg Tablet may include diarrhea, nausea, dizziness, itching, and a rapid heart rate. If any of these side effects worsen or persist, it is advisable to consult your doctor.
Avoid consuming alcohol while you are on treatment with Ivermectin. Inform your doctor if you experience any symptoms of a fast heartbeat, warmth, headache, or breathing difficulty.
Ivermectin is not recommended during pregnancy as its safety and efficacy are not completely established for pregnant women.
Ivermectin is not known to be harmful in breastfeeding women. However topical forms of this medicine should be applied carefully around the breast. Application to the nipple may increase the risk of diarrhea in the infant. Consult your doctor before using this medicine.
Avoid driving if you experience these side effects. Topical preparations containing Ivermectin have no or negligible influence on driving ability.
There is limited information available on the use of Alice 6 in patients with liver disease. Please consult your doctor.
There is limited information available on the use of Alice 6 in patients with liver disease. Please consult your doctor.
Ivermectin
Common side effects include gastrointestinal symptoms, nervous system/psychiatric symptoms, and skin reactions.
Ivermectin works by binding to the muscle and nerve cells of worms causing paralysis of the parasite. Due to inactive function, the parasite dies and the infection is treated.
Onchocerciasis, also known as river blindness, is a parasitic worm infection transmitted through the bite of black flies. It is characterized by symptoms such as skin itching and vision impairment, and if left untreated, it can lead to partial or complete vision loss. Ivermectin is commonly used to treat onchocerciasis.
Strongyloidiasis is another parasitic infection caused by Strongyloides stercoralis or sometimes S. fülleborni. Symptoms include abdominal pain, diarrhea, and dehydration, and if left untreated, it can lead to complications such as anemia. Ivermectin is effective in treating strongyloidiasis.
Scabies is a skin infection caused by the Sarcoptes scabiei mite, resulting in tiny red rashes and intense itching. Ivermectin can also be used to treat scabies effectively.
In summary, Ivermectin is a broad-spectrum antiparasitic medication used to treat various parasitic infections, including onchocerciasis, strongyloidiasis, and scabies.
Ivermectin selectively binds with high affinity to glutamate-gated chloride ion channels, which are present in nerve and muscle cells of invertebrates. This binding leads to an increase in the permeability of cell membranes to chloride ions, resulting in hyperpolarization of the nerve or muscle cell. Ultimately, this disrupts normal nerve and muscle function in the parasite, leading to its death.
For the treatment of strongyloidiasis with Alice 12 mg, the recommended dosage is a single oral dose designed to provide approximately 200 mcg/kg of body weight. The dosage guidelines are as follows:
For the treatment of onchocerciasis with Alice 12 mg, the recommended dosage is a single oral dose designed to provide approximately 150 mcg of Alice 12 mg per kg of body weight. The dosage guidelines are as follows:
These doses should be taken on an empty stomach with water. Additional doses are generally not necessary, but follow-up stool examinations should be performed to verify eradication of the infection. For onchocerciasis, the most commonly used dose interval is 12 months, but retreatment may be considered at intervals as short as 3 months for individual patients.
Before taking Alice 6mg Tablet, it's important to inform your doctor if you are taking any of the following medicines:
Additionally, regarding drug-food interactions, it's advised not to consume food two hours before or after taking Alice 6mg Tablet.
Alice 6 mg is contraindicated in patients who are hypersensitive to any component of this product.
It is not recommended to use Ivermectin for children with a body weight of less than 15 kg for scabies (a skin disorder). Additionally, it is not recommended for use in children below 5 years of age for Onchocerciasis (affects vision) and in children below 12 years of age for Strongyloidiasis (abdominal pain, low blood count caused by worms) due to insufficient safety and efficacy data available for use in these populations. Microfilaricidal drugs like Alice 6 mg may cause systemic reactions and ophthalmological reactions in patients with onchocerciasis. Patients with hyperreactive acrodermatitis may be more likely to experience severe adverse reactions.
Keep in a dry place below 30°C, protected from light, and out of the reach of children.
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