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Azicin Granules For Suspension 50ml
Azithromycin, the active component of Azicin, binds to the 50S ribosomal subunit of susceptible bacteria, inhibiting RNA-dependent protein synthesis. This blocks bacterial growth by preventing the production of essential proteins. If a dose is missed, take it as soon as remembered. Skip it if the next dose is near—do not double up.
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✅ Description:
Azicin GFS 50ml is a broad-spectrum macrolide antibiotic used to treat a variety of bacterial infections in both adults and children. These include infections of the respiratory tract, skin, eyes, ears, nose, throat, and lungs. It is also indicated in typhoid fever and certain sexually transmitted infections such as gonorrhea. Azicin works by eliminating or inhibiting the growth of bacteria responsible for these infections.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Azicin GFS 50ml is indicated for the treatment of:
- Respiratory tract infections
- Otitis media
- Skin and soft tissue infections
- Sinusitis and pharyngitis
- Community-acquired pneumonia
- Typhoid fever
- Uncomplicated gonorrhea
- Non-gonococcal urethritis and cervicitis
- Pelvic inflammatory disease (PID)
- Chlamydial infections
- Traveler’s diarrhea
- Babesiosis
- Bacterial conjunctivitis
Other infections caused by susceptible microorganisms
✔️ Dosage & Administration
Adults (Oral):
- Respiratory/Skin Infections: 500 mg once daily for 3 days.
- Chlamydial Infections/Chancroid: 1 g single dose.
- Uncomplicated Gonorrhea: 2 g single dose.
- Typhoid Fever: 1 g daily for 5 days.
- MAC prophylaxis: 1.2 g weekly; treatment: 500 mg daily with other agents.
- Granuloma Inguinale: 1 g initial dose, followed by 500 mg daily until lesions resolve.
Children (Oral):
- Otitis media: 10 mg/kg on day 1, then 5 mg/kg for 4 days; or 30 mg/kg as a single dose.
- Pharyngitis: 12 mg/kg daily for 5 days.
- Sinusitis: 10 mg/kg daily for 3 days.
- Pneumonia (CABP): 10 mg/kg on day 1, then 5 mg/kg for 4 days.
Administration Tips:
- Preferably take 1 hour before or 2 hours after meals.
- Antacids should be avoided 2 hours before and after dosing.
- Oral suspension should be taken as prescribed and evenly spaced throughout the day.
- Shake well before use.
✔️ Renal and Hepatic Dose Adjustments
- Renal impairment: No dosage adjustment typically needed.
- Hepatic impairment: Use with caution; no standard dose adjustment required.
✔️ Drug Interactions
May increase serum levels of digoxin, phenytoin, ciclosporin, terfenadine, and hexobarbital.
Antacids may reduce azithromycin absorption.
Ergot derivatives co-use may increase the risk of toxicity.
Pimozide co-administration may elevate cardiotoxic risk.
✔️ Side Effects
Common (>10%)
Diarrhea
Nausea
Abdominal pain
Loose stools
Moderate (1–10%)
Dyspepsia
Vomiting
Cramping
Flatulence
Vaginitis
Rare (<1%)
Allergic reactions
Fatigue
Rash
Headache
Dizziness
Hepatic enzyme elevations
Seizures
QT prolongation
Serious (Potentially Fatal)
Angioedema
Cholestatic jaundice
Severe allergic reactions
✔️ Contraindications
- Hypersensitivity to azithromycin, erythromycin, macrolides, or ketolides.
- Co-administration with pimozide.
- History of cholestatic jaundice or hepatic dysfunction linked to prior azithromycin use.
✔️ Pregnancy and Lactation
- Pregnancy: Available data show no significant risk to the fetus. Animal studies show no teratogenicity.
- Lactation: Excreted in breast milk; monitor infants for GI disturbances or rashes. Weigh the benefits of breastfeeding against clinical need.
✔️ Precautions
Use with caution in patients with existing liver or kidney issues.
Can prolong QT interval and cause arrhythmias—caution in patients with heart rhythm disorders, electrolyte imbalances, or those on antiarrhythmic therapy.
Monitor liver function and CBC if prolonged therapy is needed.
✔️ Storage:
The drug is to be used within 30 days after first opening. Store at 15°-25°C. Protect from light. The bottle is to be closed strongly immediately after use. Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
