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Benzapen Injection 12 lac units/vial 1pc
Benzapen is indicated for the following:
- Penicillin-sensitive infections where high initial blood levels are not required.
- Prophylaxis of penicillin-sensitive secondary infections, especially in children (e.g., continuous prophylaxis for rheumatic fever and streptococcal infections).
- Prophylaxis of streptococcal impetigo.
- Treatment of acute otitis media.
- Treatment of syphilis.
- Treatment of diphtheria carriers.
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✅ Description:
✔️ Uses of Benzapen Injection
- Bacterial infections
- Syphilis
- Prevention of rheumatic fever
✔️ How does Benzapen Injection work?
Benzapen Injection kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.
✔️ Side Effects of Benzapen Injection
- Rash
- Allergic reaction
- Injection site reactions (pain, swelling, redness)
Some patients experience a low-grade fever (up to 102°F), which typically resolves within 24-48 hours.
✔️ Quick Suggestions:
- You have been prescribed Benzapen Injection for the treatment of bacterial infections.
- It is given by an injection into a vein or muscle, or via a drip into a vein.
- Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat, or tongue, or breathing difficulties while taking this medicine.
✔️ Indication of Benzapen Injection
Benzapen Injection is used to treat Anthrax, Group A Strep. infections, Neurosyphilis, Fusobacterium infections, Diphtheria, Erysipeloid, Uncomplicated pneumococcal pneumonia, Rat bite fever, Rheumatic fever, Syphilis, Streptococcal pharyngitis
✔️ Pharmacology
Benzathine penicillin works by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs), which halts the final transpeptidation step in bacterial cell wall synthesis, ultimately leading to bacterial cell death as the cell wall breaks down.
✔️ Dosage & Administration of Benzapen Injection
Treatment of infections:
0.3 to 1.2 million units every five to seven days.
Prophylaxis of rheumatic fever:
1.2 million units every three weeks.
Specific dosages for streptococcal infections:
- Group A β-hemolytic streptococcal infections: Single intramuscular dose of 600,000 units.
- Prevention of rheumatic fever: Monthly injections of 1.2 million units.
- Acute otitis media: Single injection of 6 million units.
- Early syphilis: Single dose of 2.4 million units.
- Late syphilis: 2.4 million units weekly for three weeks.
- Neurosyphilis: 2 to 4 million units intravenously every 4 hours for 10 days, followed by 2.4 million units intramuscularly weekly for three weeks.
- Congenital syphilis: 50,000 units per kg intramuscularly in a single dose.
✔️ Interaction
No significant hazardous interactions have been reported.
✔️ Contraindications
Hypersensitivity to penicillins.
✔️ Pregnancy & Lactation
- Pregnancy category B.
Should only be administered during pregnancy if clinically justified, especially in the first trimester. - Penicillin is excreted in breast milk, so it is advisable to stop breastfeeding while on the medication.
✔️ Precautions & Warnings
- Use cautiously in patients with:
- History of hypersensitivity to cephalosporins or penicillins.
- Allergy, asthma, or seizure disorders.
- Not intended for intravenous or intra-arterial administration.
- Prolonged use may lead to superinfection (bacterial or fungal).
- Exercise caution in patients with renal impairment.
✔️ Storage:
Store between 2-8°C. Do not freeze. Keep out of the reach of children.
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accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
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