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Indications of Cipronil 500 Tablet
Ciprofloxacin is demonstrated for the treatment of Respiratory Tract Infections,Urinary tract diseases, Pelvic Fiery Infections, Irresistible The runs (Shigella dysenteriae, Vibrio cholera), Typhoid fever, Intra-abdominal contaminations, Prostatitis, Skin and Delicate Tissue Diseases, Bone and Joint Diseases, Gonorrhea, Neutropenic patients with fever due to bacterial disease, Meningitis, Surgical prophylaxis.
Pharmacology of Cipronil 500 Tablet
Ciprofloxacin may be a manufactured fluoroquinolone. It has bactericidal movement against a wide extend of gram-positive and gram-negative living beings. It hinders bacterial DNA blend by official with the bacterial enzyme-DNA gyrase and topoisomerase IV which are capable for DNA supercoiling.
Dosage & Administration of Cipronil 500 Tablet
Tablet: Adult:
Respiratory Tract Infections: 500 to 750 mg twice daily (7 to 14 days)
Urinary tract infections: 250 to 750 mg twice daily (3 to 10 days)
Pelvic Inflammatory Diseases: 500 to 750 mg twice daily (14 days)
Infectious Diarrhea (Shigella dysenteriae, Vibrio cholera): 500 mg twice daily (1 to 5 days)
Typhoid fever: 500 mg twice daily (7 days)
Intra-abdominal infections: 500 to 750 mg twice daily (5 to 14 days)
Prostatitis: 500 to 750 mg twice daily (2 to 6 weeks)
Skin and Soft Tissue Infections: 500 to 750 mg twice daily (7 to 14 days)
Bone and Joint Infections: 500 to 750 mg twice daily (max. 3 months)
Gonorrhea: 500 mg as a single dose
Neutropenic patients with fever due to bacterial infection: 500 to 750 mg twice daily co-administered with appropriate antibacterials.
Meningitis: 500 mg as a single dose.
Surgical prophylaxis: 500 mg as a single dose, 60 minutes before the procedure.
Suspension: Pediatric: 10-20 mg/kg (max. 750 mg) twice daily (10 to 21 days). The duration of therapy depends on the type and severity of the infection.Extended-release tablet: In uncomplicated urinary tract infection (acute cystitis), the recommended dose of extended-release tablet is 1000 mg tablet once daily for three days.
For IV infusion:
Urinary Tract Infection: Mild to Moderate: 200 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 12 hourly for 7-14 days
Lower Respiratory Tract infection: Mild to Moderate: 400 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 8 hourly for 7-14 days
Nosocomial Pneumonia: Mild/Moderate/Severe: 400 mg 8 hourly for 10-14 days
Skin and Skin Structure: Mild to Moderate: 400 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 8 hourly for 7-14 days
Bone and Joint Infection: Mild to Moderate: 400 mg 12 hourly for more than 4-6 weeks; Severe/Complicated: 400 mg 8 hourly for more than 4-6weeks
Intraabdominal (Acute abdomen): Complicated: 400 mg 12 hourly for 7-14 days
Acute Sinusitis: Mild/Moderate: 400 mg 12 hourly for 10 days
Chronic Bacterial Prostatitis: Mild/Moderate: 400 mg 12 hourly for 28 Days.
Interaction of Cipronil 500 Tablet
Concurrent organization of Ciprofloxacin ought to be maintained a strategic distance from with Magnesium or Aluminum containing stomach settling agents or sucralfate or with other items containing Calcium, Press or Zinc. These items may be taken two hours after or six hours some time recently Ciprofloxacin. Ciprofloxacin ought to not be taken concurrently with drain or other dairy items, since assimilation of Ciprofloxacin may be essentially decreased. Dietary calcium could be a portion of a dinner, be that as it may, does not essentially influence the assimilation of Ciprofloxacin.
Contraindications
Patients who have a known hypersensitivity to Ciprofloxacin or other quinolones should avoid it.
Side Effects of Cipronil 500 Tablet
Nausea and other gastrointestinal disorders, headache, dizziness, joint pain, and skin rashes are all possible side effects.
Pregnancy & Lactation
In pregnant women, there are no sufficient and well-controlled trials. Only if the possible benefit outweighs the danger to the fetus and mother should Ciprofloxacin be used during pregnancy. Human milk contains ciprofloxacin, which is excreted. Ciprofloxacin should not be taken during lactation due to the risk of articular injury.
Precautions & Warnings
Patients using Ciprofloxacin should be encouraged to drink plenty of water. In individuals with suspected or established CNS problems, such as epilepsy, or other variables that predispose to seizures and convulsions, it should be administered with caution. Hypokalemia should be avoided in patients with known QT prolongation.
Therapeutic Class
4-Quinolone preparations, Anti-diarrhoeal Antimicrobial drugs
Storage Conditions
Keep the temperature below 30°C and keep it away from light and moisture. Keep out of children's reach.
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