Emixef Powder for Suspension 75ml

Uses of Emixef Powder for Suspension

Emixef is indicated for the treatment of acute infections caused by susceptible microorganisms, including:

• Upper Respiratory Tract Infections (URTI): Otitis media and other URTIs where treatment failure or antibiotic resistance is likely.
• Lower Respiratory Tract Infections: Bronchitis.
• Urinary Tract Infections (UTI): Cystitis, cystourethritis, pyelonephritis.
• Typhoid: Effective in children at a dose of 5 mg/kg body weight twice daily for 10-14 days.

How does Emixef Powder for Suspension work?

Emixef 75ml kills bacteria by inhibiting the formation of their protective cell wall, which is essential for their survival.

Side Effects of Emixef Powder for Suspension

• Gastrointestinal: Diarrhea, nausea, abdominal pain, vomiting, dyspepsia.
• CNS: Headache, dizziness.
• Hypersensitivity: Rash, pruritus, urticaria, drug fever.
• Hematological: Thrombocytopenia, leukopenia, eosinophilia.
• Miscellaneous: Vaginitis, genital pruritus, transient changes in liver, and renal function tests.

Overdose Effects: Emixef Powder for Suspension

Gastric lavage may be indicated. Cefixime is not significantly removed by hemodialysis or peritoneal dialysis.

Indication: Emixef Powder for Suspension

Emixef 75ml is an antibiotic from the cephalosporin family used to treat various bacterial infections such as those of the respiratory tract, urinary tract, ear, sinuses, throat, and certain sexually transmitted diseases. It can be taken with or without food, but it is important to follow the prescribed dosage and schedule. It is essential to complete the full course of treatment even if symptoms improve to prevent the recurrence or worsening of the infection. Emixef 75ml is not effective for viral infections like the flu or the common cold, and unnecessary use can reduce its effectiveness for future bacterial infections.

Missed Dose: Emixef Powder for Suspension

If a dose is missed, take it as soon as you remember. If it is close to the time for the next dose, skip the missed dose and continue with your regular schedule. Do not take double doses.

Emixef Powder for Suspension: Dosage for Adults:

For infections such as bronchitis, pharyngitis, and urinary tract infections, the recommended dose for adults is 200-400 mg daily, either as a single dose or split into two doses. For gonorrhea, a single 400 mg dose is recommended.

Dosage for Children: Emixef Powder for Suspension

Children under 50 kg are typically given 8 mg/kg/day, divided into 1-2 doses. The dosage varies by age group and type of infection, with specific regimens for typhoid fever and other conditions. Safety in children under 6 months has not been established.

Renal Impairment: Emixef Powder for Suspension

For patients with severe kidney disease (creatinine clearance <20 ml/min), the maximum dose is 200 mg per day.

Administration of Emixef Powder for Suspension

Emixef 75ml can be taken with or without food, but taking it with food or milk can help reduce gastrointestinal discomfort. The dosage varies based on the infection and patient age, and it is important to follow the prescribed regimen.

Interaction

Emixef 75ml may increase its concentration when taken with probenecid. It may also prolong prothrombin time when used with anticoagulants, which can lead to serious complications.

Contraindications:

Emixef 75ml should not be used by individuals with known allergies to cephalosporins.

Pregnancy & Lactation

Cephalosporins, including Cefixime, have not been shown to cause adverse effects in pregnant women or their fetuses based on observational studies. However, caution is still advised. Regarding breastfeeding, it is unknown if Cefixime is present in human milk, but it is present in animal milk, so breastfeeding mothers should use it cautiously.

Precautions & Warnings

• Hypersensitivity: Cephalosporins should be used with caution in patients sensitive to penicillin due to the risk of cross-allergenicity.
• Renal Impairment: Dosage adjustments are necessary.
• Gastrointestinal Risk: Prolonged use can lead to antibiotic-associated diarrhea caused by Clostridium difficile overgrowth.

Storage:

Store below 30ºC, protected from light and moisture. Keep out of reach of children.