Estazol 400 | Uses, Dosage, Interaction, Contraindication, Price | ePharma
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Home Medicines Infection Estazol 400mg Tablet 1pc
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Estazol 400mg Tablet 1pc

Generic: Albendazole

Type: Tablet

Pack Size: 1 Pc

Estazol is indicated for the treatment of a variety of parasitic infestations, including:

  • Hookworm (Ancylostoma, Necator)
  • Roundworm (Ascaris)
  • Threadworm (Enterobius)
  • Whipworm (Trichuris)
  • Strongyloides
  • Tapeworm
  • Opisthorchis
  • Hydatid disease (Echinococcosis)

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Discount Price: ৳ 3.76
MRP: ৳ 4 6% Off

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✅ Description:

Albendazole Tablet is an antiparasitic medication used to treat infections caused by tapeworms. It works by depleting the parasite's energy sources, weakening it, and eventually leading to its death.

Take the Albendazole Tablet exactly as prescribed by your doctor. For best results, take it at the same time every day to maintain a consistent level in your body.

  • Avoid if allergic to Albendazole.
  • Inform your doctor if you have liver problems or a history of seizures.
  • Discuss your current medications with your doctor to prevent unwanted side effects.
  • Consult your doctor before use if you are pregnant, planning to become pregnant, or breastfeeding.

Safety Advices


Alcohol

It is unknown whether alcohol interacts with Estazol 400. Please consult your doctor.


Pregnancy
UNSAFE

Estazol 400 belongs to pregnancy category C. Do not take Estazol 400 if you are pregnant or planning for pregnancy as it may cause fetal harm. Please consult your doctor if you have any concerns regarding this.


Breastfeeding
UNSAFE

Do not breastfeed during and for a minimum of 5 days after treatment with Estazol 400. Please consult your doctor if you have any concerns regarding this.


Driving
CAUTION

ALBENDAZOLE may cause dizziness. Do not drive or operate machinery unless you are alert.


Kidney
CONSULT YOUR DOCTOR

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.


Liver
CONSULT YOUR DOCTOR

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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✔️ Uses of Estazol 400
  • Treats Parasitic worm infections
✔️ Side Effects of Estazol 400

Potential side effects include gastrointestinal disturbances, headache, dizziness, changes in liver enzymes, reversible alopecia, rash, fever, blood disorders (e.g., leucopenia, pancytopenia), allergic reactions, convulsions, and meningism in cases of cerebral disease.

✔️ How does Estazol 400 work?

The active constituent is converted into its sulfoxide form, leading to the degeneration of cytoplasmic microtubules and tegmental cells. This depletes the parasite's energy and disrupts metabolic processes, ultimately causing the parasite's death.

✔️ Quick Suggestions:
  • Albendazole might increase the chances of getting an infection; maintain proper hygiene, and try to stay away from people with infections, flu, or colds.
  • Regularly wash your hands with soap and water, especially after using the toilet and while eating.
  • Avoid contact with soil that may be contaminated with feces.
  • Avoid eating raw fish and meat.
  • Thoroughly cook meat before eating.
  • Wash all fruits and vegetables properly before consuming.
  • Avoid foods that have been kept open in the markets as they can be contaminated.
  • Drink boiled and purified water.
  • Regular monitoring of blood cell count and liver function is advised during treatment with Albendazole.
✔️ Indications:

Estazol is a benzimidazole anthelmintic that is effective against most nematodes and some cestodes. It exhibits vermicidal, ovicidal, and larvicidal activity, primarily by inhibiting tubulin polymerization, leading to the loss of cytoplasmic microtubules in parasites.

✔️ Pharmacology:

Albendazole, the active ingredient in Estazol, is a broad-spectrum anthelmintic. It works by blocking glucose uptake in susceptible helminths, depleting their energy reserves and ultimately leading to their death. Albendazole is metabolized in the liver to albendazole sulphoxide, which retains anthelmintic activity. It has a plasma half-life of about 8.5 hours and is excreted primarily in the urine.

✔️ Dosage and Administration :

For Adults and Children over 2 years:

  • Single-dose treatment: 400 mg (1 tablet or 10 ml suspension) for Enterobius vermicularis, Trichuris trichiura, Ascaris lumbricoides, Ancylostoma duodenale, and Necator americanus.
  • For strongyloidiasis or taeniasis: 400 mg daily for 3 consecutive days. A second course may be needed if the patient is not cured after three weeks.

For Children 1-2 years:

  • Single-dose treatment: 200 mg (5 ml suspension).

For Children under 1 year:

  • Not recommended.

For Hydatid Disease (Echinococcosis):

  • For patients over 60 kg: 400 mg twice daily for 28 days.
  • For patients under 60 kg: 15 mg/kg daily in two divided doses (maximum total daily dose: 800 mg).
  • For cystic echinococcosis, treatment cycles may be repeated after 14 days of no treatment, up to a total of 3 cycles.
  • For alveolar echinococcosis, long-term cycles of treatment may be necessary.

For Giardiasis:

  • 400 mg once daily for five days.
✔️ Interaction

No significant pharmacodynamic or pharmacokinetic interactions have been reported with Estazol.

✔️ Contraindications
  • Neonates: Not recommended.
  • Pregnancy: Should not be used during pregnancy or in women who may be pregnant.
  • Children: Dose reduction may be necessary for children weighing less than 10 kg.
  • Concurrent Diseases: No dosage adjustment is necessary for renal, hepatic, or cardiac failure patients.
✔️ Pregnancy & Lactation

Albendazole falls under the US FDA Pregnancy Category C. It should be avoided during pregnancy and lactation unless the potential benefits to the mother outweigh the risks to the fetus.

✔️ Precautions & Warnings
  • Regular blood counts and liver function tests are recommended before treatment and during each cycle.
  • Ensure pregnancy is excluded before starting treatment.
  • Continuous medical supervision is required to treat Echinococcosis, with regular monitoring of serum-transaminase concentrations and blood counts.
✔️ Storage Condition

Store in a dry place, away from light and heat. Keep out of the reach of children.

Frequently Asked Questions (FAQ)

The time taken for Estazol 400 Tablet to show its effect is 2-5 hours of its intake.

Estazol 400 Tablet may remain active in your body for an approximate duration of 2 to 3 days.

You are recommended to avoid planning for pregnancy while taking Estazol 400 as it may cause foetal harm. A pregnancy test should be done before starting the treatment with Estazol 400, and women must use effective birth-control while taking ALBENDAZOLE and for at least 1month after cessation of treatment.

The most common side effects of taking Estazol 400 are stomach pain, nausea, vomiting, dizziness, headache and increased liver enzymes. Contact your doctor if any of these side effects worsen.
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Check our pricing section for Estazol 400mg Tablet 1pc price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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