Estazol is indicated for the treatment of a variety of parasitic infestations, including:
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Albendazole Tablet is an antiparasitic medication used to treat infections caused by tapeworms. It works by depleting the parasite's energy sources, weakening it, and eventually leading to its death.
Take the Albendazole Tablet exactly as prescribed by your doctor. For best results, take it at the same time every day to maintain a consistent level in your body.
It is unknown whether alcohol interacts with Estazol 400. Please consult your doctor.
Estazol 400 belongs to pregnancy category C. Do not take Estazol 400 if you are pregnant or planning for pregnancy as it may cause fetal harm. Please consult your doctor if you have any concerns regarding this.
Do not breastfeed during and for a minimum of 5 days after treatment with Estazol 400. Please consult your doctor if you have any concerns regarding this.
ALBENDAZOLE may cause dizziness. Do not drive or operate machinery unless you are alert.
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Potential side effects include gastrointestinal disturbances, headache, dizziness, changes in liver enzymes, reversible alopecia, rash, fever, blood disorders (e.g., leucopenia, pancytopenia), allergic reactions, convulsions, and meningism in cases of cerebral disease.
The active constituent is converted into its sulfoxide form, leading to the degeneration of cytoplasmic microtubules and tegmental cells. This depletes the parasite's energy and disrupts metabolic processes, ultimately causing the parasite's death.
Estazol is a benzimidazole anthelmintic that is effective against most nematodes and some cestodes. It exhibits vermicidal, ovicidal, and larvicidal activity, primarily by inhibiting tubulin polymerization, leading to the loss of cytoplasmic microtubules in parasites.
Albendazole, the active ingredient in Estazol, is a broad-spectrum anthelmintic. It works by blocking glucose uptake in susceptible helminths, depleting their energy reserves and ultimately leading to their death. Albendazole is metabolized in the liver to albendazole sulphoxide, which retains anthelmintic activity. It has a plasma half-life of about 8.5 hours and is excreted primarily in the urine.
For Adults and Children over 2 years:
For Children 1-2 years:
For Children under 1 year:
For Hydatid Disease (Echinococcosis):
For Giardiasis:
No significant pharmacodynamic or pharmacokinetic interactions have been reported with Estazol.
Albendazole falls under the US FDA Pregnancy Category C. It should be avoided during pregnancy and lactation unless the potential benefits to the mother outweigh the risks to the fetus.
Store in a dry place, away from light and heat. Keep out of the reach of children.
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