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Flux 500mg Capsule contains Flucloxacillin, an antibiotic used to treat various bacterial infections in different parts of the body. It is effective against infections of the chest, throat, skin, and more. Symptoms of bacterial infections include fever, chills, headache, and gastrointestinal issues.
Do not use Flux 500mg Capsule if you are allergic to Flucloxacillin or other penicillin antibiotics, or if you have a history of liver diseases after taking flucloxacillin. Caution should be exercised in patients with liver or kidney problems. Pregnant and breastfeeding women should use it with caution.
Flux 500mg Capsule is not recommended for children and adolescents below 18 years and elderly patients. Common side effects include diarrhea, stomach upset, nausea, and indigestion. If any symptoms worsen, consult your doctor.
Consumption of alcohol with Flux 500mg Capsule is unsafe
Flux 500mg Capsule should be used with caution if you are pregnant or planning to get pregnant. Consult your doctor before taking Flux 500mg Capsule.
Flux 500mg Capsule should be used with caution in breastfeeding women. Consult your doctor by taking Flux 500mg Capsule.
Flux 500mg Capsule has no or negligible effect on your ability to drive and use machines.
Flux 500mg Capsule should be used with extreme caution in patients with kidney diseases due to the increased risk of worsening the patient's condition. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Flux 500mg Capsule should be used with caution in patients with a history of liver diseases due to the increased risk of serious adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Flux 500mg Capsule works by interfering with certain processes that help the bacteria to form new cell walls. This helps in stopping the growth and multiplication of bacteria and eventually kills them.
Common side effects of the Flux 500mg Capsule may include diarrhea, stomach upset, nausea, and indigestion. Uncommon side effects may include rash, itching, red/purple discolorations on the skin, and itchy welts. Rare side effects that require immediate medical attention and discontinuation of the medication include signs of allergy or hypersensitivity reactions, pseudomembranous colitis (severe bloody diarrhea), jaundice (yellowing of skin and eyes), hepatitis (inflammation of liver tissues), erythema multiforme (skin rash with red circular patches), Stevens-Johnson syndrome (severe skin rash with fever, flushing, blisters, or ulcers), and toxic epidermal necrolysis (severe rash with reddening, peeling, and swelling of the skin resembling a burn). If any of these rare side effects occur, it is essential to contact your doctor immediately.
Flucloxacillin is an antibiotic that mainly targets Gram-positive organisms, including penicillinase-producing strains. It inhibits the formation of bacterial cell walls, which are essential for their mechanical stability. This inhibition interferes with peptidoglycan synthesis, a crucial process for the bacterial cell wall. The final stage of peptidoglycan synthesis involves cross-linking with the terminal glycine residue of the pentaglycin bridge, and Flucloxacillin inhibits the transpeptidase enzyme responsible for this step.
As a bactericidal antibiotic, Flucloxacillin kills bacteria by weakening their cell walls, causing the cells to swell and rupture. The unique properties of Flucloxacillin, including resistance to penicillinase (an enzyme that degrades penicillin) and gastric acid stability, make it particularly effective against penicillinase-producing staphylococci. The presence of an acyl side chain in Flucloxacillin likely contributes to its resistance to bacterial penicillinase by inducing steric hindrance, preventing the opening of the β-lactam ring of the antibiotic.
Dosage and administration instructions for Flux 500mg Capsule:
Adult Dose:
Child Dose:
Renal Dose:
Flucloxacillin is contraindicated in penicillin-hypersensitive patients.
US FDA Pregnancy Category of Flucloxacillin is B. There are, no adequate and well-controlled studies on pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Flucloxacillin has been shown to be excreted in human milk. So, caution should be exercised when Flucloxacillin is administered to a lactating mother.
Keep in a dry place away from light and heat. Keep out of the reach of children.
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