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Nobac 400mg Tablet 10pcs
Pefloxacine 400mg Tablet is an antibiotic, used to treat bacterial infections. It is also used in treating urinary tract infections, nose, throat, skin soft tissues, and lungs (pneumonia).
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✅ Description:
Nobac (Pefloxacin) is used for treating single or mixed infections caused by susceptible microorganisms, including those resistant to other antibiotics. It treats:
- Gastrointestinal infections: Enteric fever, acute bacterial diarrhea, chronic Salmonella carriers.
- Urinary tract infections: Cystitis, pyelonephritis, prostatitis, epididymitis, uncomplicated and complicated urethritis.
- Respiratory tract infections: Pneumonia, acute and chronic bronchitis, cystic fibrosis, bronchiectasis, empyema.
- Ear, nose, and throat infections: Otitis media, otitis externa, sinusitis, tonsillitis.
- Bone and joint infections: Osteomyelitis, arthritis.
- Skin and soft tissue infections: Infected ulcer, wound infection, abscess, cellulitis, erysipelas, infected burns.
- Pelvic infections: Salpingitis, endometritis, pelvic peritonitis.
- Abdominal and hepatobiliary infections: Peritonitis, intra-abdominal abscess, cholangitis, cholecystitis, and gallbladder empyema.
- It is also used for septicemia, bacteremia, gonorrhea, endocarditis, and meningitis.
Safety Advices
Alcohol
UNSAFE
Consuming alcohol with Nobac does not cause any harmful side effects.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Nobac during pregnancy is not available. Please consult your doctor for advice.
Breastfeeding
CONSULT YOUR DOCTOR
Nobac is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into breast milk and harm the baby.
Driving
CAUTION
Nobac may cause side effects that could affect your ability to drive. Exercise caution if you experience any side effects that impair your ability to operate a vehicle.
Kidney
CAUTION
There is limited information available on the use of Nobac in patients with kidney disease. Please consult your doctor for guidance.
Liver
CAUTION
Nobac should be used with caution in patients with liver disease. Dose adjustment may be necessary. Please consult your doctor for advice.
✔️ Uses of Nobac Tablet
- Bacterial Infections
✔️ How does Nobac Tablet work?
It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.
✔️ Side Effects of Nobac Tablet
- Gastrointestinal disturbances: Epigastric pain, nausea, vomiting, diarrhea, dyspepsia.
- Central nervous system disturbances: Headache, insomnia.
- Hypersensitivity reactions: Skin rash, pruritus, photosensitization.
- Others: Myalgia, arthralgia, tendonitis, Achilles tendon rupture.
✔️ Quick Suggestions:
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Discontinue Nobac and inform your doctor immediately if you get a rash, itchy skin, swelling of your face and mouth, or difficulty in breathing.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
✔️ Pharmacology
Nobac contains pefloxacin, a synthetic fluoroquinolone antibacterial agent. It inhibits the subunit-A of DNA gyrase (Topoisomerase II), exhibiting bactericidal action with a broad spectrum of activity.
✔️ Dosage & Administration of Nobac
- Adults with normal hepatic function: 400 mg tablet every 12 hours with meals. An initial loading dose of 800 mg may be given.
- Adults with hepatic insufficiency: Adjust dosage by increasing intervals between doses. No dosage reduction is needed for renal insufficiency.
- Duration of treatment:
- Typically 5 to 10 days.
- Chronic prostatitis, cystic fibrosis, chronic Salmonella carriers: 14 days.
- Endocarditis: Up to 6 months.
- Chronic osteomyelitis: Up to 1 year.
- Gonorrhea: Single dose of 2 tablets.
✔️ Interaction
Avoid concurrent administration with antacids containing aluminum and magnesium hydroxide gel, as they reduce the absorption of Nobac.
✔️ Nobac is contraindicated in patients with:
- Hypersensitivity to quinolones
- Children under 15 years
- Pregnant and lactating women
- Inborn glucose-6-phosphate dehydrogenase deficiency
- History of tendon lesion, tendonitis, or tendon rupture
✔️ Pregnancy & Lactation
Nobac (pefloxacin) is categorized as pregnancy category C by the FDA. Use with caution.
✔️ Precautions & Warnings
- Avoid sunlight and ultraviolet exposure due to the risk of photosensitivity reactions.
- Adjust dosage for severe hepatic insufficiency.
- Inform patients about the potential for Achilles tendon pain.
✔️ Storage:
Store below 30°C, away from light and moisture. Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
