Odazyth 500mg Tablet

✔️ Uses of Odazyth 500mg Tablet

• Bacterial Infections
• Bronchitis
• Sinusitis
• Pharyngitis/Tonsillitis
• Upper Respiratory Tract Infection
• Lower Respiratory Tract Infection
• Skin And Structure Infection

✔️ How does Odazyth 500mg Tablet work?

et is an antibiotic that acts by inhibiting the synthesis of essential proteins necessary for bacterial growth and vital functions. This mechanism of action effectively hinders the growth of bacteria and prevents the spread of the infection. By disrupting protein synthesis, Odazyth 500mg Tablet targets the bacteria and helps in treating the infection.

✔️ Side Effects of

• Diarrhea
• Nausea
• Abdominal Pain
• Vomiting
• Stomach cramps,
• Flatulence
• Numbness/pickling sensation
• Loss of appetite, taste disturbance
• Visual disturbances, deafness
• Skin rash, itching
• Joint pain
• Tiredness, weakness
• Fever
• Headache
• Dizziness
• Rash
• Angioedema
• Ototoxicity
• Allergic Reaction

✔️ Quick Suggestions:

• Take Odazyth 500mg Tablet either one hour before or two hours after a meal. After completing the full course of treatment, it is recommended to take probiotics to restore healthy bacteria in the intestine that may have been affected by the antibiotic. Probiotics can help reduce the risk of antibiotic-associated diarrhea. Including fermented foods like yogurt, cheese, sauerkraut, and kimchi in your diet can also support the restoration of good bacteria in the intestine.
• Increasing the intake of fiber-enriched foods in your diet can stimulate the growth of beneficial gut bacteria. Whole grains such as whole-grain bread and brown rice are examples of fiber-rich foods that can be included.
• Avoid consuming excessive amounts of calcium-rich foods and drinks while taking Odazyth 500mg Tablet, as it may interfere with its effectiveness.
• It is advisable to avoid alcohol while taking Odazyth 500mg Tablet, as it can lead to dehydration and disrupt your sleep, making it more challenging for your body to fight off infections.
• Do not take antacids within two hours before or after taking Odazyth 500mg Tablet.
• Diarrhea may occur as a side effect of the medication but should subside once the course is completed. If the diarrhea persists or if you notice blood in your stools, inform your doctor.
• If you experience an itchy rash, swelling of the face, throat, or tongue, or difficulty breathing while taking Odazyth 500mg Tablet, stop the medication immediately and seek medical attention. These may be signs of an allergic reaction.

✔️ Indication

Odazyth 500mg Tablet is an antibiotic used to treat different types of infections caused by a variety of bacteria. 

✔️ Pharmacology

Azithromycin is a type of antibiotic known as a semisynthetic azalide. It works by blocking a process called transpeptidation. This occurs by binding to the 50S ribosomal subunit of susceptible organisms, disrupting RNA-dependent protein synthesis during the chain elongation step. In simpler terms, azithromycin interferes with the production of proteins needed for bacteria to grow and survive, ultimately inhibiting their ability to cause infection.

✔️ Dosage & Administration of Odazyth 500mg Tablet

Adult Dose:

• For respiratory tract infections and skin and soft tissue infections: 500 mg once daily for 3 days.
• For chancroid, non-gonococcal cervicitis/urethritis due to Chlamydia trachomatis, uncomplicated genital infections due to Chlamydia trachomatis: 1 g as a single dose.
• Prophylaxis of disseminated MAC infections: 1.2 g once weekly.
• Treatment or secondary prophylaxis of mycobacterial infections: 500 mg once daily in combination with other antimycobacterial.
• Uncomplicated gonorrhea: 2 g as a single dose.
• Granuloma inguinale: Initial dose of 1 g, followed by 500 mg/day until all lesions have completely healed.
• Active immunization against typhoid fever caused by Salmonella typhi: 1 g once daily for 5 days.
• Community-acquired pneumonia: 500 mg as a single IV dose for 2 days, followed by 500 mg as a single oral dose daily to complete 7-10 days of therapy.
• Pelvic inflammatory disease: 500 mg as a single IV dose for 1-2 days, followed by 250 mg as a single oral dose daily to complete a 7-day therapy.
• No dosage adjustment is needed for the elderly or patients with hepatic impairment.

Child Dose:

• The dosage varies depending on the condition and weight of the child. It is generally administered once daily for a specified number of days.
• The specific dosages for different conditions can be calculated based on the child's weight.

Renal Dose:

• No dosage adjustment is needed for patients with renal impairment.

✔️ Interaction

Drug Interactions:

• Anti-nausea pills (domperidone)
• Mental health pills (pimozide, amisulpride)
• Anti-migraine medicines (ergotamine, dihydroergotamine)
• Anti-cholesterol pills (simvastatin)
• Bladder weakness medicine (tolterodine)
• Anti-gout/arthritis medicine (colchicine)

Drug-Food Interactions: There are no significant drug-food interactions reported with Odazyth 500mg Tablet 5's. However, it is advisable to avoid consuming alcoholic beverages while taking this medication, as it may lead to increased drowsiness and dizziness.

Drug-Disease Interactions: Odazyth 500mg Tablet 5's should not be administered to individuals with the following conditions:

• Liver problems
• Muscle problem (myasthenia gravis)
• Heart rhythm disorder (arrhythmia)
• Electrolyte imbalance (low potassium or magnesium levels)
• Colitis (inflammation of the intestine)

✔️ Contraindications

Patients who have a hypersensitivity or allergic reaction to Azithromycin or any other macrolide antibiotic should not take Odazyth 500 mg Tablet. It is also not recommended to co-administer Odazyth 500 mg Tablet with ergot derivatives. Additionally, patients with hepatic diseases should avoid taking Odazyth 500 mg Tablet due to contraindications.

✔️ Pregnancy & Lactation

Azithromycin, the active ingredient in Odazyth 500 mg Tablet, is categorized as Pregnancy Category B. Studies conducted on animals have not shown any evidence of harm to the fetus. However, there are insufficient and well-controlled studies conducted on pregnant women. As animal studies do not always accurately predict human response, the use of Odazyth 500 mg Tablet during pregnancy should be considered only if there are no suitable alternatives available. The secretion of Azithromycin into breast milk is not known. Therefore, caution should be exercised when administering Odazyth 500 mg Tablet to nursing women.

✔️ Precautions & Warnings

Inform your doctor about any existing liver problems (jaundice), muscle problems (myasthenia gravis), heart rhythm disorder (arrhythmia), or electrolyte imbalance (low potassium or magnesium levels). In rare cases, Odazyth 500mg Tablet 5's may cause diarrhea, and if you experience watery or bloody diarrhea, discontinue the medication and contact your doctor. However, do not take any anti-diarrheal medication without your doctor's advice. The effect of Odazyth 500mg Tablet 5's on pregnancy is unknown, so consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding before using this medication. If you have a known allergy to azithromycin or other macrolide antibiotics, do not take Odazyth 500mg Tablet 5's. Inform your doctor if you are taking cholesterol-lowering drugs (such as simvastatin, and lovastatin), anti-gout or anti-arthritis drugs (colchicine), or medications for treating an overactive bladder (tolterodine). Odazyth 500mg Tablet is not recommended for patients with pneumonia who are considered unsuitable for oral therapy due to moderate to severe illness or risk factors.

✔️ Storage Conditions

Store below 30° C in a cold, dry, and light-protected location. Keep out of children's reach.