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Polycef 1gm/vial belongs to the first generation of cephalosporins. It works by interfering with the synthesis of the bacterial cell wall, causing the bacteria to rupture and die.
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✅ Description:
- Polycef 1gm/vial is used to treat infections caused by sensitive Gram-positive and Gram-negative bacteria, including respiratory tract infections, urinary tract infections, and skin and soft tissue infections.
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✔️ Dosage of Polycef 1gm/vial for children
- For children over nine months, the dose is 25 to 50 mg/kg/day in divided doses every 6 or 12 hours. For otitis media due to H. influenzae, 75 to 100 mg/kg/day in divided doses every 6 or 12 hours.
✔️ Dosage of Polycef 1 gm/vial
Adults:
- Respiratory and skin infections: 250 mg every 6 hours or 500 mg every 12 hours.
- Lobar pneumonia: 500 mg every 6 hours or 1 g every 12 hours.
- Urinary tract infections: 500 mg every 12 hours, up to 500 mg every 6 hours for severe cases.
Children:
- 25 to 50 mg/kg/day in divided doses every 6 or 12 hours.
- Otitis media: 75 to 100 mg/kg/day in divided doses every 6 or 12 hours, not exceeding 4 g per day.
Elderly:
- The normal adult dose is appropriate, with monitoring for renal or hepatic impairment.
✔️ Side Effects:
Common side effects include gastrointestinal disturbances and hypersensitivity reactions like rashes and urticaria. Rare side effects include dizziness, nausea, vomiting, and abdominal pain.
✔️ An Overdose of Polycef 1 gm/vial
Symptoms of overdose are nausea, vomiting, and diarrhea. Treatment is supportive, and gastric lavage may be necessary if a large amount has been ingested.
✔️ Possible drug interactions with Polycef 1 gm/vial
Concurrent use of nephrotoxic drugs like aminoglycosides may increase the risk of kidney damage. Diuretics and probenecid may also enhance renal toxicity.
✔️ Contraindications for using Polycef 1 gm/vial
Polycef should not be used in patients with known hypersensitivity to cephalosporins.
✔️ Polycef 1 gm/vial be used during pregnancy and lactation
Polycef is categorized as US FDA Pregnancy Category B. It should be used during pregnancy only if clearly needed. It is excreted in human milk, so caution is advised when administered to breastfeeding women.
✔️ precautions should be taken while using Polycef 1 gm/vial
Prolonged use may lead to superinfection due to resistant organisms. Patients with penicillin allergies should use it with caution. Dosage adjustments are necessary for patients with renal impairment.
✔️ Storage:
Reconstituted injection solutions should be used within 2 hours at room temperature or within 12 hours if refrigerated.
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