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Rozith is an antibiotic used to treat different kinds of bacterial infections in both adult's and children's eyes, skin, lungs, ears, nose, and throat. Additionally, it works well against typhoid fever and a few STDs, including gonorrhea. Rozith is a broad-spectrum antibiotic that works well to eliminate various gram-positive and gram-negative bacteria as well as other microorganisms.
It is unsafe to consume alcohol with Rozith 500mg Tablet.
The usage of Rozith 500mg Tablet during pregnancy is not sufficiently covered in the literature. As a result, unless specifically prescribed by your doctor, you should avoid using Rozith 500mg Tablet while pregnant.
Rozith 500mg Tablet is partially passed through the mother’s milk, therefore it should not be used if you are breastfeeding.
There is no information available on how Rozith 500mg Tablet affects a person's capacity for driving or operating machinery. However, Rozith 500mg Tablet may result in seizures and dizziness, so be sure you are not experiencing either before operating machinery or driving a vehicle.
You should tell your doctor if you have kidney problems as your doctor may need to alter the normal dose.
You should tell your doctor if you have liver problems as your doctor may need to alter the normal dose.
Rozith is an antibiotic. It works by preventing the synthesis of essential proteins required by bacteria to carry out vital functions. Thus, it stops the bacteria from growing and prevents the infection from spreading.
Rozith Tablet contains Azithromycin which belongs to the group of medicines called Macrolide antibiotics. It is used-
Since azithromycin is acid-stable, it can be taken orally without concern for stomach acid. It takes time to digest; on a cleansed stomach, its retention is more pronounced. For the verbal form, the adult peak development time ranges from 2.1 to 3.2 hours. Azithromycin is effectively transported to the site of contamination because of the high concentration in phagocytic cells. Extremely high azithromycin concentrations are excreted during active phagocytosis. Azithromycin concentrations in tissue can be up to 50 times higher than those in plasma. The high particle uptake and lipid clearance may be the cause of this.
Azithromycin's long half-life enables prolonged administration of a single dose while keeping bacteriostatic levels in infected tissues for a number of days. Azithromycin plasma concentrations decreased polyphonically after a single 500 mg measurement, with a plasma clearance of 630 ml/min and a terminal half-life of 68 hours. The extensive absorption and subsequent tissue clearance are thought to be the causes of the delayed terminal half-life. A major mode of elimination for azithromycin might be the nearly unchanged biliary excretion. Approximately 6% of the administered doses appeared in the urine as an unchanged drug after a week.
Microbiology: Azithromycin effectively affects the 50S ribosomal subunit of susceptible microorganisms and, as a result, interacts with a variety of microbial proteins through interferometry. Mixtures of corrosive nucleic acids are unaffected. It has been demonstrated that azithromycin is resistant to the majority of microorganism absorption limits, both in vitro and during a clinical infection:
Gram-positive bacteria are extremely active and easy to culture: Microorganisms include Streptococcus aureus, Streptococcus pneumonia, Streptococcus agalactiae, and Streptococcus pyogenes facultative. Neisseria gonorrhoeae, Haemophilus ducreyi, Moraxella catarrhalis, and Haemophilus influenzae
It is not anticipated that other microorganisms, such as Chlamydia pneumoniae, Chlamydia trachomatis, or the production of beta-pneumonia lactamases, will have an impact on the production of beta-active azithromycin.
Microbes that are aerobic and gram-positive include streptococci (C, F, and G beams) and streptococcus viridans. Gram-negative bacteria that are aerobic and simple to culture: Legionella pneumophila and Bordetella pertussis
Anaerobic microorganisms: Prevotella Livia and Peptostreptococcus species
Oral-
Adult:
Children:
Increases the levels of hexobarbital, terfenadine, digoxin, ciclosporin, and phenytoin in the blood. reduced rate of absorption when using antacids with magnesium and aluminum. elevated danger of ergot toxicity. Possible Fatal: Pimozide increases the risk of cardiotoxicity.
Patients who are extremely sensitive to azithromycin or any other macrolide antibiotic should not take azithromycin. It is not recommended to administer azithromycin and ergot derivatives simultaneously. Patients with hepatic illnesses should not take azithromycin.
The pregnancy Category of Azithromycin is B. Creature propagation ponders have illustrated that Azithromycin has no proof of hurt to the hatchling. There are no satisfactory and well-controlled considerations in pregnant ladies. Since creature generation thinks are not continuously prescient of human reaction, Azithromycin ought to be utilized amid pregnancy as it were in case satisfactory choices are not accessible. It isn't known whether Azithromycin is emitted in the breast drain. So, caution ought to be worked out when Azithromycin is managed by nursing ladies.
Keep in a dry put absent from light and warm. Keep out of the reach of children.
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