Scabo 6mg Tablet 10pcs

✔️ Uses of Scabo 6

Treatment of parasitic infections.

✔️ How does Scabo 6 work?

It works by binding to the muscle and nerve cells of worms, causing their paralysis and death. This treats your infection.

✔️ Adverse Reaction of Scabo 6

For Strongyloidiasis:
In four clinical studies involving 109 patients, the following side effects were reported:

• General: Fatigue (0.9%), abdominal pain (0.9%).
• Gastrointestinal: Anorexia (0.9%), constipation (0.9%), diarrhea (1.8%), nausea (1.8%), vomiting (0.9%).
• Nervous System: Dizziness (2.8%), drowsiness (0.9%), vertigo (0.9%), tremor (0.9%).
• Skin: Itching (2.8%), rash (0.9%), urticaria (0.9%).

For Onchocerciasis:
Side effects reported include:

• Joint pain or synovitis (19.3%), lymph node enlargement, and tenderness in the axillary (11%), cervical (5.3%), inguinal (12.6%), and other areas.
• Itching (27.5%), skin rashes (22.7%), fever (22.6%).
• Eye-related reactions include abnormal sensation, eyelid swelling, conjunctivitis, anterior uveitis, and keratitis. These conditions are generally not severe and resolve without corticosteroid treatment.

✔️ Quick Suggestions:

• Ivermectin helps treat parasitic infections of your intestinal tract, skin, and eyes.
• Take it on an empty stomach with a full glass of water.
• You usually need to take it only once to get rid of your infection. However, if you don't feel better after taking it, talk to your doctor.
• Drink lots of fluids and avoid caffeine when taking this medication.
• Before taking Ivermectin, inform your doctor if you have: a condition called loa loa (eye infection), a weak immune system (immunity disorder)

✔️ Indication: Scabo 6

Scabo 6 (antiparasitic medicine) works by binding to the nerve and muscle cells of parasites leading to their death, thus helping to manage various parasitic infections. 

✔️ Pharmacology

Scabo 6 mg binds selectively and strongly to glutamate-gated chloride ion channels, which are found in the nerve and muscle cells of invertebrates. This increases the permeability of cell membranes to chloride ions, leading to hyperpolarization and eventual death of the parasite.

✔️ Dosage & Administration of Scabo 6

For Strongyloidiasis:
The recommended dose is a single oral dose of approximately 200 mcg/kg of body weight. Tablets should be taken on an empty stomach with water, and in most cases, no additional doses are required. Follow-up stool tests are advised to confirm the infection's eradication.

Dosage guidelines for Strongyloidiasis based on body weight:

• 15-24 kg: 3 mg
• 25-35 kg: 6 mg
• 36-50 kg: 9 mg
• 51-65 kg: 12 mg
• 66-79 kg: 15 mg

80 kg: 200 mcg/kg

For Onchocerciasis:
The recommended dose is a single oral dose of approximately 150 mcg/kg of body weight, taken on an empty stomach with water. Retreatments are usually spaced at 12-month intervals, though in some cases, they can be administered every 3 months.

Dosage guidelines for Onchocerciasis based on body weight:

• 15-25 kg: 3 mg
• 26-44 kg: 6 mg
• 45-64 kg: 9 mg
• 65-84 kg: 12 mg

85 kg: 150 mcg/kg

Pediatric Use:

• The safety and efficacy of Scabo 6 mg in children weighing less than 15 kg have not been established.

Geriatric Use:  

• There is insufficient data to determine if elderly patients respond differently than younger patients to the Scabo 6 mg treatment.

✔️ Interaction

Post-marketing reports indicate that Scabo 6 mg can occasionally cause an increase in INR (International Normalized Ratio) when taken with warfarin.

✔️ Contraindications

Scabo 6  is contraindicated in patients with known hypersensitivity to any of its components.

✔️ Pregnancy & Lactation

Pregnancy:
Scabo 6 mg is classified as Pregnancy Category C. Although there is no direct evidence of selective harm to a fetus, adequate studies in pregnant women are lacking. Its use during pregnancy is not recommended unless the benefits outweigh the risks.

Breastfeeding:
Scabo 6 mg is excreted in low amounts in breast milk. Treatment in breastfeeding mothers should only proceed if the risks of delaying treatment are higher than the potential risk to the infant.

✔️ Precautions & Warnings

• In patients with onchocerciasis, treatment with Scabo 6 mg can cause allergic and inflammatory reactions (Mazzotti reaction) due to the death of microfilariae.
• The reactions can be managed with oral hydration, intravenous saline, corticosteroids, antihistamines, or aspirin for mild to moderate cases. Severe reactions in patients with hyperreactive acrodermatitis or coinfection with Loa loa may include encephalopathy, back pain, conjunctival hemorrhage, and mental confusion, among others.

✔️ Storage Condition

Store in a dry place, below 30°C, away from light. Keep out of the reach of children.