Kanopas 20 is a prescription medication used in adults who have diabetes-related kidney disease
- Reduces the chance of worsening kidney problems and lowers the risk of severe heart issues.
- Helps prevent further decline in kidney function
- Reduces the risk of heart attacks
- Reduces the requirement for hospitalization caused by heart problems
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Finerenone is prescribed for managing chronic kidney disease (CKD) linked to type 2 diabetes. It is effective in reducing the risk of severe kidney function decline, end-stage kidney disease, cardiovascular death, non-fatal heart attacks, and hospitalization due to heart failure. It also significantly lowers the risk of new-onset heart failure.
Consult your doctor as the interaction with alcohol is unknown.
Use with caution; not recommended unless necessary.
Unsafe; can harm your child.
Generally safe, but be cautious if experiencing weakness or tiredness.
Safe when prescribed by a doctor.
Exercise caution if you have liver impairment; consult your doctor.
Management of chronic kidney disease associated with type 2 diabetes
Finerenone contains finerenone, a non-steroidal mineralocorticoid receptor antagonist. It blocks certain hormones that can cause damage to the kidneys and heart.
Possible Side Effects:
Finerenone is used to treat patients with chronic renal damage caused by type 2 diabetes.
Recommended Dosage-
For patients who are unable to swallow whole tablets, Finerenone may be crushed and mixed with water or soft foods.
The recommended starting dosage: is 10 mg or 20 mg orally once daily based on estimated glomerular filtration rate (eGFR) and serum potassium thresholds. Increase dosage after 4 weeks to the target dose of 20 mg once daily, based on eGFR and serum potassium thresholds. Tablets may be taken with or without food.
Contraindicated in concomitant use with strong CYP3A4 inhibitors & patients with adrenal insufficiency.
There are no available data on Kanopas 20 use in pregnancy to evaluate for a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes. Animal studies have shown developmental toxicity at exposures about 4 times those expected in humans. The clinical significance of these findings is unclear. The estimated background risk of major birth defects and miscarriage for the indicated population is unknown. All pregnancies have a background risk of birth defect, loss, or other adverse outcomes. In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2 to 4% and 15 to 20%, respectively.
There are no data on the presence of finerenone or its metabolite in human milk, the effects on the breastfed infant, or the effects of the drug on milk production. In a pre-and postnatal developmental toxicity study in rats, increased pup mortality and lower pup weight were observed at about 4 times the AUC unbound expected in humans. These findings suggest that finerenone is present in rat milk. When a drug is present in animal milk, the drug will likely be present in human milk. Because of the potential risk to breastfed infants from exposure to Finerenone, avoid breastfeeding during treatment and for 1 day after treatment.
Store in a cool, dry place away from sunlight.
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