A medication called Ursocol 300mg Tablet is used to dissolve some types of gallstones, stop them from forming, and treat primary biliary cirrhosis, a type of liver disease. It is a bile acid that aids in the breakdown of cholesterol that has crystallized into gallbladder stones.
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Avoid consumption of alcohol while taking Ursocol 300mg Tablet as it may cause increased dizziness and liver damage.
Ursocol 300mg Tablet should be used in pregnant women only if considered clearly necessary by the doctor. If you are pregnant or think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking Ursocol 300mg Tablet.
Ursocol 300mg Tablet should be used with caution in breastfeeding women as it is not known if it passes through breast milk. Consult your doctor if you are breastfeeding or about to start breastfeeding before taking Ursocol 300mg Tablet.
Ursocol 300mg Tablet has no or negligible effect on driving or using machines.
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Ursocol 300mg Tablet should be used with caution in patients with liver diseases. Your doctor might advise you for frequent liver examinations and tests during the treatment. Consult your doctor before taking the Ursocol 300mg Tablet
By improving bile flow through the liver and preserving liver cells, Ursocol 300mg Tablet helps to reduce elevated liver enzyme levels. Ursocol 300mg Tablet is a bile concentrate that reduces biliary cholesterol by blocking the synthesis of new cholesterol through intestinal absorption. Lowering cholesterol levels progressively solubilizes cholesterol from gallstones, resulting in their disintegration.
Ursodeoxycholic Acid helps to treat
A naturally occurring bile acid called ursodeoxycholic acid is used to treat a number of hepatobiliary conditions. The action of ursodeoxycholic acid is based on a decrease in bile cholesterol synthesis. By lowering dietary cholesterol absorption, reducing hepatic cholesterol production, and not impairing bile acid synthesis, ursodeoxycholic acid achieves this.
Bile's composition shifts from supersaturated to unsaturated as a result. Because it encourages the growth of liquid cholesterol crystal complexes, ursodeoxycholic acid also facilitates the movement of cholesterol from the gallbladder into the intestine for excretion.
Ursodeoxycholic acid is completely absorbed in the upper gut. Between 30 and 150 minutes pass before serum concentration reaches its maximum. The percentage of absorption varies from 60% to 80%. After absorption, ursodeoxycholic acid travels to the portal vein where it is taken up by the liver, conjugated with an amino acid (glycine or taurine), and then released into the hepatic bile ducts. Ursodeoxycholic acid is present in very small amounts in the blood and is only slightly excreted in the urine. The biological half-life of ursodeoxycholic acid ranges from 3.5 to 5.8 days.
Gallstone dissolution: 8–12 mg/kg/day, given either all at once at night or in divided doses.
Take Ursocol 300mg Tablet in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ursocol 300 Tablet is to be taken with food.
Ursodeoxycholic Acid should not be used with medicines that raise bile cholesterol, such as oestrogenic hormones. Concurrent administration of Ursodeoxycholic acid with bile-acid binding medications such as antacids, charcoal, or cholestyramine should be avoided, since this may impair the efficacy of Ursodeoxycholic acid therapy.
Inflammatory intestinal illness, non-functioning gallbladder, calcified and pigmented gallstones
Category B pregnancy. In pregnancy, no indication of danger has been documented. It has been successfully used to treat cholestasis in pregnant women throughout the third trimester with no adverse effects. Breastfeeding problems have not been recorded in humans.
It is important to follow the precautions and warnings provided by the manufacturer and your healthcare provider before taking Ursocol 300mg Tablet.
Store below 25° C. Protected from light and moisture. Keep the medicine out of the reach of children.
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