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Cariso 250 Tablet 1 Strip
Cariso is prescribed for:
- Alleviating discomfort linked to acute, painful musculoskeletal conditions in adults
- Promoting sedation and easing anxiety in patients suffering from severe pain
- Serving as a supportive therapy in physical rehabilitation for musculoskeletal injuries
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✅ Description:
Carisoprodol acts as an indirect agonist of the GABA-A receptor, enhancing chloride ion conductance in the central nervous system. This results in sedative, anxiolytic, and muscle-relaxant effects. Its active metabolite, meprobamate, contributes to its calming and muscle-relaxing properties. Carisoprodol works centrally by interrupting nerve signals between the brain/spinal cord and muscles, thereby relieving muscle spasms. It does not act directly on skeletal muscle fibers.
✔️ Dosage & Administration
Adults (18+ years):
250–350 mg orally, three times a day and at bedtime.
Maximum recommended treatment duration: 2 to 3 weeks
Special Populations:
Use cautiously in individuals with hepatic or renal impairment or reduced CYP2C19 enzyme activity.
✔️ Pregnancy & Lactation
Pregnancy Category C: Use only if clearly needed.
May cause reduced milk production or infant sedation when used by breastfeeding mothers. Exercise caution.
✔️ Overdose Management
- Cariso overdose may cause profound CNS depression, coma, respiratory failure, hypotension, and seizures.
- Do NOT induce vomiting due to sedation risk.
- Consider gastric lavage within 1 hour of ingestion.
- Supportive care includes fluid resuscitation, vasopressors, and airway management (including intubation if needed).
- Seizures should be managed with IV benzodiazepines; if persistent, phenobarbital may be considered.
✔️ Side Effects
Drowsiness
Dizziness
Headache
✔️ Drug Interactions
- Concurrent use with CNS depressants (e.g., alcohol, opioids, benzodiazepines, tricyclic antidepressants) may enhance sedative effects.
- CYP2C19 inhibitors (e.g., Omeprazole, Fluvoxamine) may increase Cariso levels.
- CYP2C19 inducers (e.g., Rifampin) may reduce Cariso exposure.
✔️ Contraindications
- Known hypersensitivity to carisoprodol or carbamate derivatives (e.g., meprobamate)
- History of acute intermittent porphyria
✔️ Precautions & Warnings
- May impair alertness—avoid driving or operating heavy machinery.
- Increased sedative effects when used with alcohol or other CNS depressants.
- Risk of dependence, withdrawal, and abuse with prolonged use.
- Seizures may occur, particularly in overdose or abrupt withdrawal.
✔️ Storage
Store at 20°C–25°C in a cool, dry environment away from direct light. Keep out of reach of children.
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information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
