Flexibac 10mg Tablet

✔️ Uses of Flexibac 10mg Tablet

• Treats Muscle Spasms (painful muscle contractions)

✔️ Side Effects of Flexibac 10mg Tablet

• Nausea
• Vomiting
• Tiredness
• Sleepiness
• Weak limbs
• Muscle pain
• Constipation,
• Dry mouth
• Diarrhea,
• Lack of sleep, nightmares
• Confusion, hallucination
• Breathing difficulties
• Vision problems
• Urge to pass urine
• Feeling unsteady or shaky
• Feeling faint due to low blood pressure
• Skin rash, sweating
• Increased liver enzymes

✔️ Quick Suggestions:

• Flexibac 10mg Tablet provides relief from rigidity, tension, and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system.
• Take it with or after food or a glass of milk.
• Flexibac 10 may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
• Avoid consuming alcohol when taking Flexibac 10 as it may cause excessive drowsiness.
• Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
• Do not stop taking it suddenly without talking to your doctor if you've been on it for a long time.

✔️ Indication of Flexibac 10mg Tablet

Baclofen is used to treat skeletal muscle spasms caused by rheumatic disorders, spinal cord injuries, and other spinal diseases, as well as spasticity caused by multiple sclerosis, flexor spasms and pain, clonus, and muscular rigidity. Cerebrovascular accidents, tumors, and degenerative brain disease are all possible causes.

✔️ Pharmacology

Baclofen is a medication that works by activating GABAB receptors in the spinal cord, which inhibits the release of glutamate and aspartate, thereby reducing monosynaptic and polysynaptic reflexes. It may also cause central nervous system depression by acting at intraspinal sites. Additionally, Baclofen has pain-relieving properties as well.

✔️ Dosage & Administration of Flexibac 10mg Tablet

• The recommended adult oral dose for spasticity is to start with 5 mg three times daily for three days, then increase to 10 mg three times daily for another three days. The dosage may then be increased gradually at similar intervals until the desired effect is achieved or up to a maximum of 80 mg per day. The elderly should initiate with lower doses.
• For children with spasticity, the oral dose is 0.75-2 mg/kg daily. The initial dose may be 2.5 mg four times daily, increased gradually every three days until the desired effect is achieved. The maintenance dose is 30-60 mg daily for 6-10-year-olds, 20-30 mg daily for 2-6-year-olds, and 10-20 mg daily for children aged 12 months to 2 years. The maximum dose for children over 10 years old is 2.5 mg/kg daily.
• Dose reduction may be necessary for individuals with renal impairment.

✔️ Interaction

• Baclofen may cause increased sedation when combined with central nervous system depressants, alcohol, or synthetic opiates. Respiratory depression is also a possibility.
• Because combining Baclofen with antihypertensives is likely to result in a greater drop in blood pressure, the antihypertensive medication dosage should be adjusted accordingly.

✔️ Contraindications

Baclofen is not recommended for patients who are hypersensitive to any of the product's ingredients.

✔️ Pregnancy & Lactation

Baclofen is not safe to use during pregnancy, according to pregnancy category B3. Baclofen passes through the placental barrier. Baclofen should only be given to pregnant women if the physician believes that the potential benefits outweigh the potential risks. Baclofen is excreted in breast milk, but the evidence so far suggests that the amounts are so small that no adverse effects on the infant are expected.

✔️ Precautions & Warnings

• Lower doses should be administered to patients with impaired renal function or those undergoing chronic hemodialysis (approximately 5 mg per day).
• Spasticity patients, as well as those with psychotic disorders, schizophrenia, depressive or manic disorders, or confusional states, should be treated with caution and closely monitored, as these disorders can worsen.
• Notify your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.

✔️ Storage Conditions

Store below 30°C, away from light, in a cool, dry place. Keep out of children's reach.